Results 171 to 180 of about 58,042,140 (212)

Promoter Methylation of HIV Coreceptor-Related Genes CCR5 and CXCR4: Original Research. [PDF]

Viruses
Esman A, Salamaikina S, Kirichenko A, Vinokurov M, Fomina D, Sikamov K, Syrkina A, Pokrovskaya A, Akimkin V.   +8 more
europepmc   +1 more source

The C‐terminal truncated splicing variant of NK1R negatively modulates substance P‐stimulated NK1R signaling

FEBS Open Bio, EarlyView.
The neurokinin 1 receptor exists as full‐length (NK1L) and C‐terminally truncated (NK1S) splice variants. We show that NK1S heterodimerizes with NK1L, impairing Gαq coupling and Ca2+ mobilization while enhancing β‐arrestin1 recruitment. NK1S suppresses substance P‐driven gene expression and cell migration, revealing NK1S as an endogenous biased ...
Lan Phuong Nguyen, Duc Trung Nguyen, Minyoung Cho, Jihun Kim, Soyeon In, Thai Uy Nguyen, Sunghoon Hurh, Beom Jin Park, Jong‐Ik Hwang   +8 more
wiley   +1 more source

Evaluation of Efficacy of Platelet Rich Fibrin in Healing Process Post Oral and Maxillofacial Surgery: An Original Research. [PDF]

J Pharm Bioallied Sci
Antony D, Pokala S, Nelson A, Bhoi S, Ibrahim M, Srivastava AP, Dalapati C, Thakkar R.   +7 more
europepmc   +1 more source

The C‐terminal domain of yeast Arginyltransferase1 is essential for its catalytic activity

FEBS Open Bio, EarlyView.
Arginyltransferase 1 (Ate1), a eukaryotic enzyme, catalyses arginylation, transferring arginine from tRNA‐Arg to the amino terminus of the target protein. Overexpression of Ate1 in yeast is lethal and is dependent on arginylation. This study elucidates how mutations in the cofactor‐binding and active site of Ate1 and truncation of its structural ...
Vikas Kumar Yadav, Shweta Shweta, Manisha Malhotra, Vikash Maurya, Akhilesh Kumar   +4 more
wiley   +1 more source

Original research: factors related to persistent amblyopia after surgical correction in unilateral congenital blepharoptosis. [PDF]

BMC Ophthalmol
Chen YH, Huang PW, Tsai YJ.
europepmc   +1 more source

Genetic dissection of human ABCE1 in yeast reveals separable requirements for ribosome recycling and suppression of aberrant reinitiation

FEBS Open Bio, EarlyView.
Human ABCE1 cannot functionally replace its yeast ortholog. Yeast–human chimera analysis identified NBD1 as a major interspecies barrier. Genetic screening yielded hABCE1 revertants that rescue yeast viability but fail to suppress aberrant translation reinitiation in the 3′ UTR.
Eriko Nakata, Yuxin Li, Kei Endo, Koichi Ito   +3 more
wiley   +1 more source

A Multidisciplinary Clinical Approach in Decision-Making in Complex Dento-Alveolar Trauma in the Maxillofacial Region: An Original Research. [PDF]

J Pharm Bioallied Sci
Patidar A, Garg S, Pradhan PK, Kumari P, Raheja A, Das SS.   +5 more
europepmc   +1 more source

MARK4 enhances stress granule formation under oxidative stress and increases tau accumulation

FEBS Open Bio, EarlyView.
MARK4 (red dots) localizes to stress granules (orange dots) and promotes their formation under oxidative stress by modulating TIA1 (blue dots). MARK4 and TIA1 synergistically increase tau (purple) accumulation, and the reduction of the TIA1 ortholog suppresses neurodegeneration in a fly model.
Sho Nakajima, Kotone Watanabe, Grigorii Sultanakhmetov, Aoi Fukuchi, Keiya Ito, Sawako Shimizu, Taro Saito, Akiko Asada, Kanae Ando   +8 more
wiley   +1 more source

Assessment of Impact of Various Contraceptive Methods on Irregualrity of Menstrual Cycles: An Original Research.

J Pharm Bioallied Sci
Bharti N, Salgotra M, Khokhar M, Bhargava R, Puthumana KJ, Attar JR, Paulose L, Tiwari HD.   +7 more
europepmc   +1 more source

Effectiveness of 10% Carbamide Peroxide in the Home Bleaching Technique on Vital Teeth: An Original Research. [PDF]

J Pharm Bioallied Sci
Jain S, Rai A, Puri S, Kahate MM, Jain A, Mishra R.   +5 more
europepmc   +1 more source