Results 31 to 40 of about 2,067,751 (218)
An open investigation of the reproducibility of cancer biology research
eLife, 2014 It is widely believed that research that builds upon previously published findings has reproduced the original work. However, it is rare for researchers to perform or publish direct replications of existing results.
Timothy M Errington +5 more
doaj +1 more source
FEBS Letters, EarlyView.Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil +4 more
wiley +1 more source
EXARC Journal, 2019 Experimental archaeology, especially experimental lithic technology, has not yet been established as a line of research in Brazil (or most of South America).
João Carlos Moreno De Sousa
doaj
A score test for the agronomical overlap effect in a two-way classification model
Agronomía Colombiana, 2014 In some agricultural research, a treatment applied to an experimental unit may affect the response in the neighboring experimental units. This phenomenon is known as overlap. In this article, a test to evaluate this effect in the Draper and Guttman model
Aquiles Darghan +2 more
doaj +1 more source
FEBS Letters, EarlyView.Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure +3 more
wiley +1 more source
FEBS Letters, EarlyView.This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley +1 more source
COMPARATIVE EVALUATION OF THE EFFICACY AND SAFETY OF VALPROIC ACID DERIVATIVES
Эпилепсия и пароксизмальные состояния, 2016 : this article discusses the comparative efficacy and safety of valproic acid derivatives (various salts), and the original of generic drugs based on it, are the literature data and the results of our experimental and clinical studies on the ...
O. L. Badalyan +5 more
doaj
Giovanni Canestrini’s models of Leonardo da Vinci’s friction experiments
Science Museum Group Journal, 2016 Among the exhibits at the 2016 Leonardo da Vinci exhibition at the Science Museum, London, was one that purported to illustrate Leonardo’s experiments on friction.
Professor Ian Hutchings
doaj +1 more source
International Journal of Distributed Sensor Networks, 2020 In order to guarantee the tag identification accuracy and efficiency in mobile radio frequency identification system, it is necessary to estimate the tags’ arrival rate before performing identification.
Liqian Zhang, Xueliang Fu, Honghui Li
doaj +1 more source
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
FEBS Letters, EarlyView.Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source