Results 61 to 70 of about 2,067,751 (218)
Cancer Management and Research, 2021 Fan J, Kang X, Zhao L, Zheng Y, Yang J, Li D. Cancer Manag Res. 2020;12:4699–4714. The Editor and Publisher of Cancer Management and Research wish to retract the published article.
Fan J +5 more
doaj
Molecular Oncology, EarlyView.Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura +19 more
wiley +1 more source
Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining
Molecular Oncology, EarlyView.IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis +3 more
wiley +1 more source
Data in Brief, 2018 This data article is related to the original research article “Diurnal rhythms in peripheral blood immune cell numbers of domestic pigs” of Engert et al. [1] and describes diurnal rhythms in the number of CD8α− and CD8α+ γδ T cells in peripheral blood of
Larissa C. Engert +3 more
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Molecular Oncology, EarlyView.We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober +16 more
wiley +1 more source
Seismic Behavior of Retaining Walls: A Critical Review of Experimental and Numerical Findings
GeotechnicsFor reliable seismic design of earth-retaining structures, it is critical to accurately assess the magnitude and distribution of dynamic earth pressures.
Sabahat Ali Khan +2 more
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Top 50 most-cited articles in medicine and science in football
BMJ Open Sport & Exercise Medicine, 2018 Objectives To conduct a comprehensive mapping analysis to the scientific literature published in football aiming to identify the areas of bigger interest and potential for further exploration.Methods The data were obtained by a search conducted on the ...
João Brito +3 more
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MITF maintains genome stability in nonmelanocyte lineages
Molecular Oncology, EarlyView.MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir +13 more
wiley +1 more source
SONG TO CHESS: TEACH CHESS WITH SONGS
Tendencias Pedagógicas, 2015 This article summarizes the Grade Work submitted as a requirement to qualify for Masters in Education, minor in Technology and Development of Instruction, by the co-author of the article in the Pedagogical University Experimental Libertador de Caracas ...
Joaquín Fernández Amigo +1 more
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Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma
Molecular Oncology, EarlyView.Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski +10 more
wiley +1 more source