Results 121 to 130 of about 50,064 (277)

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

Molecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq, Marc Terrones, Felicia Rodrigues Fortes, Anne Schepers, Alessia Denis, Christophe Deben, Ken Op de Beeck, Guy Van Camp, Geert Vandeweyer   +8 more
wiley   +1 more source

Evaluación de un paciente con dolor epigástrico y hallazgos sincrónicos infrecuentes. [PDF]

Acta Gastroenterol Latinoam
Grove RL, Soloaga D, Spina JC.
europepmc   +1 more source

Problemas originales propuestos en examen. Dibujo II

, 1990
Esta obra contiene los problemas originales propuestos en examen por el autor, desde 1981 hasta 1996. Se ha dividido el libro en dos grandes bloques, uno de enunciados y otro de soluciones, correspondientes a la asignatura de dibujo II, del plan de 1982.
Oti Velasco, Jesús
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[Quality of care in university podiatry. Analysis of the patient satisfaction questionnaire]. [PDF]

Aten Primaria
Arnao Villegas MY.
europepmc   +1 more source

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

FEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj, Eline M. F. de Lange, Klaas A. Sjollema, Ben N. G. Giepmans   +3 more
wiley   +1 more source

[Translation and cross-cultural adaptation to the Iceland-Family Perceived Support Questionnaire to the Spanish context]. [PDF]

An Sist Sanit Navar
Benbelkheir Núñez B, Alfaro-Díaz C, Pueyo-Garrigues M, Carrión Torre M, Esandi Larramendi N.   +4 more
europepmc   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

FEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point, Wafaa Achache, Janïs Laudouze, Eliana Sepulveda Ramos, Mickaël Maziero, Céline Crauste, Stéphane Canaan, Pierre Santucci   +7 more
wiley   +1 more source

[Anatomy of the Forest Plot graphic]. [PDF]

Rev Med Inst Mex Seguro Soc
Rojas-Jiménez D, Castañeda-Aca AI, Alonzo-Martínez JJ, López-Sánchez M, Roy-García IA, Rivas-Ruiz R.   +5 more
europepmc   +1 more source

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

FEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source

Catalogue des lithographies originales de Henri Fantin-Latour : exposition périodiques d'estampes, troisième exposition (1er juin 1899) /

, 1899
At head of title: Musée national du Luxembourg.Includes bibliographical references (p.
Bénédite, Léonce, 1859-1925., Fantin-Latour, Henri, 1836-1904., Musée national du Luxembourg (France)   +2 more
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