Results 161 to 170 of about 2,084 (261)
Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function
FEBS Open Bio, EarlyView.We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke +4 more
wiley +1 more source
Originalism and the Importance of Constitutional Aspirations
, 1997 Originalism and nonoriginalism represent competing approaches to constitutional interpretation. Originalism insists that the understandings or intentions of the Constitution\u27s drafters and ratifiers provide the principal, if not the exclusive ...
Saphire, Richard B.
core +1 more source
Commentary: The origins of fetal origins [PDF]
International Journal of Epidemiology, 2016 openaire +2 more sources
FEBS Open Bio, EarlyView.Bioscience students were asked for their opinions on the value and teaching of skills. 204 responded that teamwork, time management and study skills are necessary to reach University, that scientific writing, research, laboratory and presentation skills are taught effectively during their studies, while other skills are gained inherently through study ...
Janella Borrell, Susan Crennell
wiley +1 more source
FEBS Open Bio, EarlyView.This paper reveals how human lactoferrin–albumin fusion (hLF‐HSA) potently suppresses lung adenocarcinoma cell migration. hLF‐HSA upregulates NHE7, leading to Golgi alkalization, disruption of the Golgi secretome, downregulation of MMP1, and reversal of EMT. These findings suggest a novel Golgi‐targeting strategy to suppress cancer cell migration.
Hana Nopia +3 more
wiley +1 more source
, 2014 Reviewing Frank B. Cross, The Failed Promise of Originalism; Mark A. Graber, A New Introduction to American Constitutionalism; and John O. McGinnis & Michael B.
Compton, John W.
core +1 more source
A super SDM (species distribution model) 'in the cloud' for better habitat-association inference with a 'big data' application of the Great Gray Owl for Alaska. [PDF]
Sci RepHuettmann F +7 more
europepmc +1 more source
YIPFα1A expression is regulated by multilayered molecular mechanisms
FEBS Open Bio, EarlyView.YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji +2 more
wiley +1 more source
Ideas and ideation in geographical political economy. [PDF]
Prog Hum GeogrPeck J, Meulbroek C, Phillips R.
europepmc +1 more source