Results 111 to 120 of about 4,673,795 (354)

Disparities in Proton Radiation Utilization for HPV‐Associated Oropharyngeal Cancer Following TORS

Head &Neck, EarlyView.
ABSTRACT Introduction Racial, socioeconomic, and geographic disparities in receipt of proton radiation have been reported. Whether disparities exist for oropharyngeal squamous cell carcinoma (OPSCC) is not well studied. Methods Patients with HPV‐associated OPSCC treated with transoral robotic surgery (TORS) and adjuvant radiation from 2016 to 2023 were
Jane Y. Tong, Vera Bzhilyanskaya, Jason K. Molitoris, Matthew J. Ferris, Kyle M. Hatten   +4 more
wiley   +1 more source

Impact of diabetes on the prognosis of patients with oral and oropharyngeal cancer: A meta‐analysis

Journal of Diabetes Investigation
Aims/Introduction Diabetes has been related to an increased risk of oral cancer. Nevertheless, the impact of diabetes on the outcome of individuals with oral and oropharyngeal cancer is not clear.
Wei Xu, Zhi Chen, Laijian Zhang
doaj   +1 more source

Activation of Akt at T308 and S473 in alcohol, tobacco and HPV-induced HNSCC:is there evidence to support a prognostic or diagnostic role? [PDF]

, 2014
BACKGROUND: Tobacco, alcohol and HPV infection are associated with increased risk of HNSCC. However, little is known about the underlying signaling events influencing risk.
Cochrane, Lynda, Ellis, Ian R., Islam, Mohammad R., Jones, Sarah J., Macluskey, Michaelina   +4 more
core   +3 more sources

OPTIMA: a phase II dose and volume de-escalation trial for human papillomavirus-positive oropharyngeal cancer

Annals of Oncology, 2019
BACKGROUND Patients with HPV+ oropharyngeal squamous cell carcinoma were assigned to dose and volume de-escalated radiotherapy (RT) or chemoradiotherapy (CRT) based on response to induction chemotherapy in an effort to limit treatment-related toxicity ...
Tanguy Y Seiwert, C. Foster, E. Blair, Theodore Karrison, N. Agrawal, J. Melotek, L. Portugal, R. Brisson, A. Dekker, Sara E Kochanny, Z. Gooi, M. Lingen, V. Villaflor, Daniel Ginat, D. Haraf, E. Vokes   +15 more
semanticscholar   +1 more source

Neutrophil to Lymphocyte and Lymphocyte to Monocyte Ratios Predict Improved Survival and Response to Induction Chemotherapy in Locally Advanced Squamous Cell Carcinoma of the Larynx

Head &Neck, EarlyView.
ABSTRACT Background University of Michigan Cancer Center (UMCC) protocol 9520 treated stage III/IV locally advanced squamous cell carcinoma of the larynx (LASCCL) with cisplatin and 5‐fluorouracil to select for definitive therapy based on response.
Zachary Risch, Emily Bellile, Moneb S. Bughrara, Paul L. Swiecicki, Keith Casper, Kelly Malloy, Norman Hogikyan, Matthew Spector, Andrew Shuman, Chaz Stucken, Steven Chinn, Douglas C. Chepeha, Shruti Jolly, Michelle Mierzwa, Carol Bradford, Avraham Eisbruch, Thomas Carey, Mark Prince, Gregory T. Wolf, Francis P. Worden   +19 more
wiley   +1 more source

Chloride Intracellular Channel 2 Can Function as a Malignant Factor in Head and Neck Squamous Cell Carcinoma

Head &Neck, EarlyView.
ABSTRACT Background The association of chloride intracellular channel 2 (CLIC2) with tumors has remained unclear. However, recently, CLIC2 was found to exhibit antitumor properties in some tumors. In this study, we aimed to evaluate the clinical relevance of CLIC2 expression in head and neck squamous cell carcinoma (HNSCC) to determine whether it ...
Yuki Hosokawa, Shoko Miyoshi, Yuji Hayashi, Yuki Irifune, Eriko Sato, Sohei Mitani, Mohammed Choudhury, Hajime Yano, Junya Tanaka, Naohito Hato   +9 more
wiley   +1 more source

Phase 1b/2a trial of the superoxide dismutase mimetic GC4419 to reduce chemoradiotherapy-induced oral mucositis in patients with oral cavity or oropharyngeal carcinoma [PDF]

, 2018
PURPOSE: To assess the safety of the superoxide dismutase mimetic GC4419 in combination with radiation and concurrent cisplatin for patients with oral cavity or oropharyngeal cancer (OCC) and to assess the potential of GC4419 to reduce severe oral ...
Adkins, Douglas, Agarwala, Sanjiv S, Allen, Bryan G, Anderson, Carryn M, Brill, Jeffrey M, Buatti, John M, Chen, Yuhchyau, Holmlund, Jon T, Lee, Christopher M, Mould, Diane R, Sonis, Stephen T, Sun, Wenqing, Venigalla, Madhavi L, Zhen, Weining   +13 more
core   +2 more sources

Salivary IL-17A, IL-17F, and TNF-α Are Associated with Disease Advancement in Patients with Oral and Oropharyngeal Cancer

Journal of Immunological Research, 2020
Delayed diagnosis of oral cavity and oropharyngeal cancer is associated with a poor prognosis. Despite progress in systemic therapy and radiotherapy, there has only been a slight improvement in the five‐year survival rate.
Kinga Zielińska, B. Karczmarek-Borowska, K. Kwaśniak, Justyna Czarnik-Kwaśniak, Aleksandra Ludwin, B. Lewandowski, J. Tabarkiewicz   +6 more
semanticscholar   +1 more source

Nomogram for Predicting Osteoradionecrosis After Fibula Free Flap for Mandibular Reconstruction

Head &Neck, EarlyView.
ABSTRACT Background Osteoradionecrosis (ORN) is a severe complication following radiotherapy (RT), particularly after mandibular reconstruction with a fibula free flap. Risk prediction remains challenging due to limited data. Methods We conducted a multicenter retrospective study including 294 patients who underwent fibula free flap reconstruction and ...
Andrea Costantino, Bianca Festa, Filippo Marchi, Chung‐Kan Tsao, Raul Pellini, Luca Gazzini, Peter T. Dzięgielewski, Mario Ciniglio, Francesco Mazzola, Luca Calabrese, Antonio Sarno, Giampiero Parrinello, Linda Chow, Jyh‐Kwei Chen, Giorgio Peretti, Armando De Virgilio   +15 more
wiley   +1 more source

Single‐item discrimination of quality‐of‐life–altering dysphagia among 714 long‐term oropharyngeal cancer survivors: Comparison of patient‐reported outcome measures of swallowing

Cancer, 2019
Two patient‐reported outcomes (PROs) of swallowing and their correlation to quality of life (QOL) were compared in long‐term survivors of oropharyngeal cancer (OPC).
Stephen R Grant, Mona Kamal, A. Mohamed, Jhankruti Zaveri, Martha P. Barrow, G. Gunn, S. Lai, J. Lewin, D. Rosenthal, X. Wang, C. Fuller, K. Hutcheson   +11 more
semanticscholar   +1 more source