Results 91 to 100 of about 337,580 (303)

A Hierarchical Transformer Encoder to Improve Entire Neoplasm Segmentation on Whole Slide Image of Hepatocellular Carcinoma [PDF]

arXiv, 2023
In digital histopathology, entire neoplasm segmentation on Whole Slide Image (WSI) of Hepatocellular Carcinoma (HCC) plays an important role, especially as a preprocessing filter to automatically exclude healthy tissue, in histological molecular correlations mining and other downstream histopathological tasks.
arxiv  

First‐in‐Human Single and Multiple Ascending Dose Studies of Balinatunfib, a Small Molecule Inhibitor of TNFR1 Signaling in Healthy Participants

Clinical Pharmacology &Therapeutics, EarlyView.
Oral small molecule inhibitors of tumor necrosis factor alpha (TNFα) are emerging as attractive therapeutic agents for the treatment of various autoimmune diseases. Balinatunfib (SAR441566), a novel oral inhibitor of tumor necrosis factor receptor 1 (TNFR1) signaling, changes the configuration of the soluble TNFα (sTNFα) trimer and prevents its ...
Nassr Nassr, Faiza Rharbaoui, Dietmar Weitz, Johann Gassenhuber, Markus Rehberg, Markus Kohlmann, Fabienne Schumacher, Amel Lahmar, Andreas Kovar, Laurent Perrin, Frank‐Dietrich Wagner, Maria Wiekowski, Mai Anh Nguyen   +12 more
wiley   +1 more source

A Review and Comparative Analysis of Transoral Surgical Treatment versus Conservative Management in Early-Stage Oropharyngeal Cancer

Journal of Personalized Medicine
Introduction: Oropharyngeal cancer requires a comprehensive evaluation of treatment options, including surgery, radiation therapy, and chemotherapy. It is crucial to customize these treatments based on the stage of the tumor and the overall health of the
S. Rujan, Ș. Berteșteanu, R. Grigore, Bogdan Popescu, M. Condeescu-Cojocarița, Nicolaescu Alexandru, Gloria Simona Bertesteanu, Teodora Elena Schipor-Diaconu, A. Cirstea, Mihai Dumitru Tudosie, Irina-Doinita Popescu, B. Taher   +11 more
semanticscholar   +1 more source

A Case Series and Literature Review of Angiosarcoma With Malignant Effusion—A Challenging Cytologic Diagnosis With Dire Prognostic Implications

Diagnostic Cytopathology, EarlyView.
ABSTRACT Angiosarcoma with malignant effusion is an uncommon yet clinically aggressive presentation, which poses as a diagnostic pitfall with its overlapping cytomorphologic features with metastatic adenocarcinoma. In this article, two cases reported in the literature were reviewed for cytology, immunocytochemistry, and clinical course.
Jamie C. Y. Lam, Iris Y. H. Liu, Joanna K. M. Ng, Joshua J. X. Li   +3 more
wiley   +1 more source

Lingual Schwannoma-A Common Tumour at Uncommon Site in a Paediatric Patient: A Case Report and Review of the Literature [PDF]

Journal of Clinical and Diagnostic Research, 2018
Schwannomas are infrequent tumours of oral cavity that are not routinely included in the differential diagnosis of oropharyngeal masses. The tumour presents with non-specific clinical symptoms and is clinically indistinguishable from varied soft tissue
Alka Mary Mathai, K Preetha, S Valsaladevi, C Karthikeyan   +3 more
doaj   +1 more source

Hierarchical Phenotyping and Graph Modeling of Spatial Architecture in Lymphoid Neoplasms [PDF]

arXiv, 2021
The cells and their spatial patterns in the tumor microenvironment (TME) play a key role in tumor evolution, and yet the latter remains an understudied topic in computational pathology. This study, to the best of our knowledge, is among the first to hybridize local and global graph methods to profile orchestration and interaction of cellular components.
arxiv  

Oropharyngeal Lipoma: A Rare Case of Dysphagia.

Ear, nose, & throat journal
Lipomas are benign and slow-growing neoplasms that typically develop in the subcutaneous tissue. They rarely occur in the upper aerodigestive tract. Oropharyngeal lipomas are rare. They represent 0.5% of all neoplasms of the head and neck.
Ghada Yousfi, Oumaima Gharss, Yasmine Sghaier, Nesrine Sellami, R. Kharrat, T. Boudawara, Boutheina Hammemi, Ilhem Chareffedine   +7 more
semanticscholar   +1 more source

Studying the emergence of invasiveness in tumours using game theory [PDF]

, 2008
Tumour cells have to acquire a number of capabilities if a neoplasm is to become a cancer. One of these key capabilities is increased motility which is needed for invasion of other tissues and metastasis. This paper presents a qualitative mathematical model based on game theory and computer simulations using cellular automata.
arxiv   +1 more source

A Clinical Case of Application of Dalargin with Carbohydrate Load for Anesthesia in a Patient with Oropharyngeal Cancer

Nauka molodykh (Eruditio Juvenium)
INTRODUCTION: Surgical treatment is an inseparable part of modern medicine and is widely used to treat different diseases. It is of priority in treatment of newly diagnosed malignant neoplasms of the oropharyngeal region.
Danil N. Vasil’yev, D. E. Kulbakin, E. Choynzonov, S. V. Avdeyev, D. Azovskaya, Andrey A. Li, Vladimir V. Fal’tin, Vasiliy M. Odyshev, Viktor A. Krinitsin   +8 more
semanticscholar   +1 more source

Circulating Tumor HPV‐DNA in the Management of HPV‐Positive Oropharyngeal Carcinoma: A Systematic Review

Head &Neck, EarlyView.
ABSTRACT Purpose Blood‐borne, cell‐free DNA has been proposed as a means of individualizing the management of human papillomavirus (HPV)‐positive oropharyngeal carcinoma. Methods and Materials This study was designed based on the Preferred Reporting Items for Systematic Review and Meta‐Analysis Protocols (PRISMA‐P) statement. A comprehensive literature
Allen M. Chen, Tjoson Tjoa, William B. Armstrong   +2 more
wiley   +1 more source