Results 41 to 50 of about 60,617 (213)

Intensive Swallowing Rehabilitation for Head and Neck Cancer Survivors With Chronic Dysphagia: Outcomes From a Prospective Multicentre Cohort Study With 6‐Month Follow‐Up

Head &Neck, EarlyView.
ABSTRACT Background Chronic dysphagia persists in some head and neck cancer (HNC) survivors despite preventive exercises, negatively impacting quality of life. Evidence for effective rehabilitation strategies remains limited. Methods This prospective cohort study included 34 HNC survivors (≥ 1 year post‐treatment) who completed a 3‐week intensive ...
J. I. Oldenbeuving, L. van der Molen, J. T. Groothuis, J. G. Kalf   +3 more
wiley   +1 more source

Cigarette Smoke Exposure Attenuates T2R‐Mediated Apoptosis in Head and Neck Squamous Cell Carcinoma

Head &Neck, EarlyView.
ABSTRACT Background Tobacco use is associated with worse outcomes in head and neck squamous cell carcinoma (HNSCC). Bitter taste receptor (T2R) activation induces apoptosis via calcium‐dependent signaling, and higher T2R expression correlates with increased survival in HNSCC.
Kyle Polen, Sarah Sywanycz, Gavin Turner, Brianna L. Hill, Lily Huang, Zoey A. Miller, Casey Hanna, Lovely Raghav, Devraj Basu, Robert J. Lee, Ryan M. Carey   +10 more
wiley   +1 more source

Impact of Smoking on Treatment Outcomes in Patients With Human Papillomavirus‐Related Oropharyngeal Cancer

Head &Neck, EarlyView.
ABSTRACT Background Patients with HPV+ oropharyngeal cancer (OPC) have worse outcomes with longer smoking history (≥ 10 pack‐years). This has been confirmed in trials of primary radiotherapy but not surgery, suggesting differential smoking impact by treatment received. We assessed smoking‐related outcomes at a single institution.
Michelle M. Kwan, Latifa A. Bazzi, Zequn Sun, Dayton Rand, Asher Park, Shravan Asthana, Alexis Larson, Poonam Yadav, Bharat B. Mittal, Adil Akthar, Sarah Kramer, Jochen H. Lorch, Sandeep Samant, Urjeet Patel, Michelle L. Mierzwa, Leila J. Mady, Katelyn O. Stepan, Laila A. Gharzai   +17 more
wiley   +1 more source

Comparison of In‐Office and General Anesthesia Biopsies for Oropharyngeal Squamous Cell Carcinoma in a Public Healthcare System

Head &Neck, EarlyView.
ABSTRACT Background We compared treatment delays, costs, and management impact between oropharyngeal squamous cell carcinoma (OPSCC) patients undergoing in‐office versus general anesthesia panendoscopy‐guided biopsies in two large tertiary centers in a public healthcare system. Methods All OPSCC patients included were treated between 2010 and 2024 with
Samuel Bellavance, Michel Khoury, Justine Colivas, Jonathan Primiani, Gabriel Dayan, Eric Bissada, Tareck Ayad, Apostolos Christopoulos, Jean‐Claude Tabet, Louis Guertin, Paul Tabet   +10 more
wiley   +1 more source

Associations Between Preexisting Depression and Anxiety and Postoperative Outcomes Among Medicare Beneficiaries Undergoing Head and Neck Cancer Surgery

Head &Neck, EarlyView.
ABSTRACT Introduction Depression and anxiety are common in patients with head and neck cancer (HNC), but their impacts on postoperative outcomes after major HNC surgery are not well defined. We evaluated whether preexisting, clinically diagnosed depression or anxiety independently predicted short‐term postoperative outcomes among adults undergoing HNC ...
Xiaodan Hu, Daniel Gilmore, Ericka L. Erickson, Catherine T. Haring, Kyle VanKoevering, Nolan B. Seim, Stephen Y. Kang, James W. Rocco, Ann Scheck McAlearney, Lauren E. Miller   +9 more
wiley   +1 more source

Longitudinal Swallowing and Salivary Changes With CLR 131 and Re‐Irradiation in Recurrent Head and Neck Cancer

Head &Neck, EarlyView.
ABSTRACT Background Patients with recurrent head and neck cancer (HNC) often present with severe, persistent dysphagia and xerostomia following prior chemoradiation. Although swallowing impairments and salivary dysfunction have been reported in this population, prior longitudinal studies have not examined changes in salivary composition or how these ...
Jenni Wu, Sara Gustafson, Meredith Hyun, Roxana Alexandridis, Mark Nicosia, Timothy McCulloch, Justine Bruce, Randall Kimple, Nicole Rogus‐Pulia   +8 more
wiley   +1 more source

Variations in Treatment Prescription and Survival Outcomes Between Older and Younger Patients With Mucosal Head and Neck Squamous Cell Carcinoma Treated With Radiotherapy

Head &Neck, EarlyView.
ABSTRACT Purpose To investigate treatment variations and outcomes between older (≥ 70 years) and younger (< 70 years) patients with mucosal head and neck squamous cell carcinoma (mHNSCC) treated with radiotherapy. Methods A multicenter retrospective review of patients diagnosed from 2010 to 2018 was conducted.
Farhannah Aly, Joseph Descallar, Purnima Sundaresan, Alexis Andrew Miller, Lois Holloway, Shalini Vinod   +5 more
wiley   +1 more source

“It's the Exact Same Treatment … Except Only 5 Min Away”: A RE‐AIM Evaluation of a Speech‐Language Pathology Shared‐Care Model for Rural Patients With Head and Neck Cancer

Head &Neck, EarlyView.
ABSTRACT Background Challenges accessing post‐treatment speech‐language pathology (SLP) services can add to treatment burden for rural patients with head and neck cancer (HNC). Hence, the aim of this study was to evaluate a shared‐care SLP service designed to support local SLP access for patients with HNC, using the RE‐AIM framework.
Corey Patterson, Elizabeth C. Ward, Rebecca L. Packer, Jasmine Foley, Laurelie R. Wishart, Clare L. Burns, Sally Pether, Wendy Comben   +7 more
wiley   +1 more source

Incidence and Site‐Specific Risk Factors of Jaw Osteoradionecrosis for Head and Neck Patients in the IMRT/VMAT Era: Evidence From a Large, Hospital‐Based Cohort

Head &Neck, EarlyView.
ABSTRACT Purpose Osteoradionecrosis (ORN) of the jaw remains a serious late complication of head and neck cancer (HNC) radiotherapy. Although intensity‐modulated radiotherapy (IMRT) and volumetric‐modulated arc radiotherapy (VMAT) are expected to reduce ORN risk, large real‐world data in the modern era are limited.
Fang‐Yu Wu, Hui‐Hsin Ko, Hsiang‐Fong Kao, Shih‐Jung Cheng   +3 more
wiley   +1 more source

External Validation of Pre‐Treatment Primary Tumor Volume as a Prognostic Factor in Head and Neck Cancer Treated With (Chemo)Radiotherapy

Head &Neck, EarlyView.
ABSTRACT Background Primary tumor volume (GTVp) is a key prognostic factor in oropharyngeal squamous cell carcinoma (OPSCC) treated with radiotherapy. We aimed to externally validate this association and assess its relevance in other head and neck sites.
Gabriel Adrian, Andre Haraldsson Änghede, Lachlan McDowell, Maria Gebre‐Medhin   +3 more
wiley   +1 more source