Results 181 to 190 of about 124,112 (267)

Uncovering Biogas Outcomes: Tales of Hubris, Hope, and Failure From Southern Malawi

Natural Resources Forum, EarlyView.
ABSTRACT The purpose of this article is to speak directly to biogas failure. Over the past two decades, immense amounts of money have been spent by African governments, private individuals, and most conspicuously, international aid agencies and donors, on countless biogas projects in every country on the continent.
Marc Kalina, Jonathan Kwangulero, Jonathan Òlal Ogwang, Natalie Boyd Williams, Elizabeth Tilley   +4 more
wiley   +1 more source

Orphan GPCRs in diabetes mellitus: metabolic control, inflammation, and drug development. [PDF]

Front Endocrinol (Lausanne)
Chandrabose S, Muniyandi V, Geddawy A, Thiyagarajan R, Murugesan A, Kandhavelu M.   +5 more
europepmc   +1 more source

The Issue of Pre‐Islamic Arabic Christian Poetry Revisited

Arabian Archaeology and Epigraphy, EarlyView.
ABSTRACT Is only very little Arabic Christian poetry extant from pre‐Islamic times? While distancing myself from Louis Cheikho's (1859–1927) view that almost all pre‐Islamic poets were Christians, I contend in this article that some of them indeed were.
Ilkka Lindstedt
wiley   +1 more source

Orphan Designation for Drugs Approved in the United States and European Union: A Comparative Analysis. [PDF]

Clin Pharmacol Ther
Costa E, Ross JS, Kesselheim AS.
europepmc   +1 more source

Status of ash (Fraxinus spp.) in mixed hardwood post‐outbreak forests near the epicentre of the emerald ash borer invasion

Agricultural and Forest Entomology, EarlyView.
The persistence and health of ash populations were characterized in post‐outbreak forests near the epicentre of the emerald ash borer (EAB) invasion in North America. Regenerating ash remained abundant, but densities of understory ash were higher in wetlands (hydric), while ash remained at the seedling stage in riparian (mesic) and upland (xeric ...
Aaron Tayal, Kayla I. Perry
wiley   +1 more source

Rare disease patients protection: theoretical discussion and institutional construction of orphan drug designation in China. [PDF]

Orphanet J Rare Dis
Zhao X, Zhang M, Zhang M.
europepmc   +1 more source

Australian Royal Commissions Into Child Welfare, Abuse and Protection

Australian Journal of Politics &History, EarlyView.
ABSTRACT Both nationally and internationally, the Australian Royal Commission into Institutional Responses to Child Sexual Abuse (RCIRCSA) is widely viewed as a remarkably successful public inquiry. Unlike many other commissions, it was stable, attracted little controversy, was highly regarded, and led to extensive legal, regulatory and policy reform ...
Shurlee Swain, Katie Wright
wiley   +1 more source

Rebalancing innovation, affordability, and access for orphan drugs in the European Union. [PDF]

Lancet Reg Health Eur
Stevens H, Siotis G, Castanheira M, Dewatripont M, Akodad S, Daems S, Fischer A, Goldman M.   +7 more
europepmc   +1 more source

Autosomal Dominant Hyper‐IgE Syndrome Patients Retain IL10‐Producing preTh17‐Cells That Are Activated by Opportunistic Pathogens and Support IgE Production

Allergy, EarlyView.
IL‐10 producing CCR6+Th‐cells are central memory T‐cells that express ROR‐γt and differentiate to Th17‐cells via an autocrine loop of STAT3‐activating cytokines (preTh17). STAT3‐deficient AD‐HIES patients lack Th17‐ and Tfh17‐cells but retain preTh17‐ and Th1/17‐cells.
Giorgia Moschetti, Chiara Vasco, Francesca Clemente, Paola Larghi, Sara Maioli, Edoardo Scarpa, Elena Carelli, Nadia Pulvirenti, Maria Lucia Sarnicola, Mariacristina Crosti, Manal Bel Imam, Willem van de Veen, Loris Rizzello, Sergio Abrignani, Lucia A. Baselli, Rosa Maria Dellepiane, Maria Carrabba, Giovanna Fabio, Jens Geginat   +18 more
wiley   +1 more source

Use of real-world evidence in the U.S. Food and Drug Administration and the European Medicines Agency approvals of oncology products supported by single-arm trials (2022-2025). [PDF]

Oncologist
Su L, Chen L, Mamtani R, Betigeri S, Hubbard R, Burcu M.   +5 more
europepmc   +1 more source