Results 61 to 70 of about 124,112 (267)

Kramerman, Harry (Box 90, Folder 24)

, 1976
Series VIII: Audiocassettes features informal oral histories about the Hebrew Orphan Asylum and its alumni.Digital recordingDigital finding ...
Hebrew Orphan Asylum of New York
core  

Beyond the label: Rethinking off‐label drug use in paediatrics. Towards a scientifically grounded and safer future for paediatric pharmacotherapy

British Journal of Clinical Pharmacology, EarlyView.
Abstract Despite regulatory progress being made in the past two decades, off‐label drug use in paediatrics remains pervasive, with prevalence estimated between 3% and 97% of prescriptions across different clinical settings. Off‐label use—defined as prescribing outside the conditions described in the Summary of Product Characteristics (SmPC)—is often ...
Tjitske M. van der Zanden, Miriam G. Mooij, Matthijs de Hoog, Saskia N. de Wildt   +3 more
wiley   +1 more source

Assessment of joint health in patients receiving prophylaxis for haemophilia A: a cross-sectional survey in five European countries

BMJ Open
Objectives To evaluate joint health, pain and health-related quality of life (HRQoL) in patients with moderate/severe haemophilia A in Europe.Design Multinational, cross-sectional survey, with retrospective data collection.
Zalmai Hakimi, Hortensia De la Corte-Rodríguez, Linda Bystrická, Nathan Ball, Stevie Olsen, Keisha Golden, Nana Kragh   +6 more
doaj   +1 more source

Siegel, Harry (Box 91, Folder 15)

, 1977
Series VIII: Audiocassettes features informal oral histories about the Hebrew Orphan Asylum and its alumni.Digital recordingDigital finding ...
Hebrew Orphan Asylum of New York
core  

Through the lens of marketing authorization holders: experience in use of real‐world data and real‐world evidence in drug development and regulatory submissions in EU

British Journal of Clinical Pharmacology, EarlyView.
Abstract Aim The aim of this study was to assess the general and product‐specific experiences of MAHs use of RWD/RWE in medicines development and in their regulatory submissions, and to explore organizational aspects of MAHs related to RWD/RWE. Methods An electronic survey was conducted, and information collected directly from MAHs.
Sini M. Eskola, Aleksandar Gigov, Hubertus G. M. Leufkens, Andrew Bate, Marie Louise De Bruin, Helga Gardarsdottir   +5 more
wiley   +1 more source

The Kelch-Repeat Superfamily Gene SiNL4 Regulates the Leaf Width in Foxtail Millet

Plants
The Kelch-repeat superfamily genes played important roles in regulating plant growth and development; however, their functions in foxtail millet (Setaria italica) have not yet been characterized.
Yuqin Zhao, Yixuan Ma, Yanyu Yang, Lejie Yang, Lu Chen, Tianguo Wang, Shiyuan Wang, Kai Zhao, Xiaorui Li, Shuqi Dong, Hongzhi Wang, Xiaoqian Chu, Jiagang Wang, Lulu Gao, Guanghui Yang   +14 more
doaj   +1 more source

Raskin, Hy (Box 91, Folder 8)

, 1976
Series VIII: Audiocassettes features informal oral histories about the Hebrew Orphan Asylum and its alumni.Digital recordingDigital finding ...
Hebrew Orphan Asylum of New York
core  

Do drugs approved via expedited approval pathways have therapeutic advantages? A systematic review and meta‐analysis

British Journal of Clinical Pharmacology, EarlyView.
Regulators use expedited approval pathways to speed market approval and patient access to promising new drugs. However, there is uncertainty about whether these pathways are successful in approving drugs with significant therapeutic advantages. This systematic review aims to examine the safety, effectiveness and cost‐effectiveness of drugs approved via
Ashleigh Hooimeyer, Eliza J. McEwin, Zhicheng Wang, Joel Lexchin, Barbara Mintzes   +4 more
wiley   +1 more source

Siegel, Harry and Sally (Box 91, Folder 16)

, 1987
Series VIII: Audiocassettes features informal oral histories about the Hebrew Orphan Asylum and its alumni.Digital recordingDigital finding ...
Hebrew Orphan Asylum of New York
core  

A discrete choice experiment investigating preferences for funding drugs used to treat orphan diseases: an exploratory study [PDF]

, 2010
Policy debate about funding criteria for drugs used to treat rare, orphan diseases is gaining prominence. This study presents evidence from a discrete choice experiment using a convenience sample of university students to investigate individual ...
Jeremiah Hurley, Mentzakis, Emmanouil, Stefanowska, Patricia, Emmanouil Mentzakis, Patricia Stefanowska, Hurley, Jeremiah   +5 more
core   +1 more source