Results 171 to 180 of about 3,868,024 (353)

Promoting Academic Entrepreneurship in Europe and the United States: Creating an Intellectual Property Regime to Facilitate the Efficient Transfer of Knowledge from the Lab to the Patient [PDF]

, 2015
In 2014, the European Commission announced the launch of a study of knowledge transfer by public research organizations and other institutes of higher learning “to determine which additional measures might be needed to ensure an optimal flow of knowledge
Bagley, Constance E., Tvarnø, Christina D.   +1 more
core   +1 more source

Artificial intelligence streamlines scientific discovery of drug–target interactions

British Journal of Pharmacology, EarlyView.
Abstract Drug discovery is a complicated process through which new therapeutics are identified to prevent and treat specific diseases. Identification of drug–target interactions (DTIs) stands as a pivotal aspect within the realm of drug discovery and development. The traditional process of drug discovery, especially identification of DTIs, is marked by
Yuxin Yang, Feixiong Cheng
wiley   +1 more source

Impact of changes in regulatory framework on approval of medicines for rare diseases and applicability to market access policies

Frontiers in Medicine
The introduction of the Orphan Drug Act in the USA in 1983, followed by adoption of the Orphan Drug Regulation No 141/2000 in the EU in 2000, led to a change in landscape of drug development for rare diseases.
Fran Brown, Maximilian Vargas, Sanja Stanisic, Geoff Fatzinger, Oxana Iliach   +4 more
doaj   +1 more source

Access to orphan drugs despite poor quality of clinical evidence [PDF]

, 2010
Alain Dupont, Philippe B. Van Wilder
openalex   +1 more source

Race, Money and Medicines [PDF]

, 2006
Taking notice of race is both risky and inevitable, in medicine no less than in other endeavors. The literature on race as a classifying tool in clinical research poses this core dilemma: On the one hand, race can be a useful stand-in for unstudied ...
Bloche, Maxwell Gregg
core   +1 more source

Contribution of chloride channels to the action potential and contraction in human myometrium during labour

British Journal of Pharmacology, EarlyView.
Background and purpose The action potential underpinning calcium delivery for contraction in human uterine smooth muscle (myometrium) consists of an initial spike(s) followed by a prolonged plateau of depolarization to ⁓ −25 mV. The plateau duration establishes contraction duration, especially important in labour.
Helena C. Parkington, Ranga E. Siriwardhana, Mary A. Tonta, Shaun P. Brennecke, Penelope M. Sheehan, Marianne Tare, Harold A. Coleman   +6 more
wiley   +1 more source

Orphanhood Status and Antecedents to Placement Among a Multinational Sample of Adults With Care Experience

Child &Family Social Work, EarlyView.
ABSTRACT Globally, millions of children are adopted or placed in alternative care settings (i.e., residential, foster, or kinship care). The current study explores the factors leading to separation from parents and adoption or placement in alternative care by investigating orphanhood status, perceived antecedents to placement, types of alternative care
Nicole Gilbertson Wilke, Jedd Medefind, Amanda Hiles Howard   +2 more
wiley   +1 more source

オーファンドラッグ(orphan drug)

, 2000
三宅 良彦
openalex   +2 more sources

Health technology assessment: oncology drugs with orphan designation as an example [PDF]

, 2010
Claudia Wild
openalex   +1 more source

IMPROVE 2023: The 2nd International Meeting on Pathway‐Related Obesity: Vision & Evidence

Clinical Obesity, EarlyView.
ABSTRACT A total of 150 clinicians and researchers representing 19 countries came together in person and online to participate in the highly anticipated 2nd International Meeting on Pathway‐Related Obesity: Vision & Evidence (IMPROVE), held on 13–15 December 2023 in Paris, France.
Karine Clément, Erica L. T. van den Akker, Jesús Argente, Phil Beales, Metin Cetiner, Béatrice Dubern, Sadaf Farooqi, Aurélie Gouronc, Peter Kühnen, Johanne Le Beyec, Louis Lebreton, David Meeker, Hermann L. Müller, Jean Muller, Christine Poitou, Patrick Sleiman, Christian Vaisse, Martin Wabitsch, Jacques Young, Hélène Dollfus   +19 more
wiley   +1 more source