Results 191 to 200 of about 3,868,024 (353)
Advances in orphan drug development: Time to change the status and stereotype. [PDF]
Perspect Clin Res, 2022 Thakur S.
europepmc +1 more source
First International South Caucasian Conference on Rare Diseases and Orphan Drugs [PDF]
, 2010 openalex +1 more source
Epilepsia, EarlyView.Abstract Objective Benzodiazepine immediate‐use seizure medications (ISMs; also called rescue therapies) are used to treat seizure clusters/acute repetitive seizures in patients with epilepsy. In the United States, diazepam nasal spray is an approved ISM for patients ≥2 years of age.
Eric B. Segal +7 more
wiley +1 more source
Trends in orphan drug use and spending among children and adolescents during 2010-2020 in Korea. [PDF]
Front Pharmacol, 2022 Oh JY, Lee JY, Kim DS.
europepmc +1 more source
Limitations of drug registries to evaluate orphan medicinal products for the treatment of lysosomal storage disorders [PDF]
, 2011 Carla E. M. Hollak +3 more
openalex +1 more source
The hope for neglected diseases: R&D incentives [PDF]
Neglected diseases are neglected because they cannot generate enough return on R&D to pharmaceutical firms. This paper analyzes and compares existing proposals for public intervention in R&D for neglected diseases.
Brigitte Granville, Eshref Trushin
core
Topiramate for the treatment of neonatal seizures and beyond
Epilepsia, EarlyView.Abstract Acute symptomatic neonatal seizures are one of the most common neurological disorders in newborns admitted to neonatal intensive care units and require prompt treatment. Up to 50% of neonatal seizures are refractory to first‐line medications such as phenobarbital (PB), and another 30% fail second‐line therapy.
Wolfgang Löscher, Janet S. Soul
wiley +1 more source
Rare disease patients in India are rarely involved in international orphan drug trials. [PDF]
PLOS Glob Public Health, 2022 Chakraborty M +3 more
europepmc +1 more source
Orphan Drug Status Granted for MORAb-003 Monoclonal Antibody for Treatment of Ovarian Cancer
, 2006 NULL AUTHOR_ID
openalex +1 more source