Results 131 to 140 of about 88,754 (289)
Assessment of the availability of repurposed orphan drugs in India. [PDF]
PLOS Glob Public Health, 2023 Rajueni K, Chakraborty Choudhury M.
europepmc +1 more source
Two-stage public-private partnership proposal for R&D on neglected diseases [PDF]
We propose a 2-stage procurement model of public-private partnership to provide better incentives for R&D on neglected diseases. The model combines advance market commitment, subsidized clinical trials, and rewards based on therapeutical contributions of
Brigitte Granville, Eshref Trushin
core
Med Research, EarlyView.ABSTRACT Circadian rhythms orchestrate cardiovascular physiology by regulating immune and inflammatory pathways. Disruption of these rhythms profoundly alters vascular homeostasis, thereby promoting the onset and progression of cardiovascular diseases (CVD).
Tian Zhang +22 more
wiley +1 more source
Arbor: Ciencia, Pensamiento y Cultura, 2018 Orphan drugs are intended for the treatment of diseases of low prevalence, also known as rare diseases. Research and development into new therapies for this heterogeneous group of diseases presents a number of well-recognized difficulties. One of these is that the small number of patients affected jeopardizes the economic return on the investment made ...
Fontanet Sacristán, Juan Manuel +1 more
openaire +1 more source
Social Security Programs Throughout the World: The Americas, 2011 [PDF]
, 2012 [Excerpt] This fourth issue in the current four-volume series of Social Security Programs Throughout the World reports on the countries of the Americas.
International Social Security Association +1 more
core +1 more source
Engineering compact Physalis peruviana (goldenberry) to promote its potential as a global crop
PLANTS, PEOPLE, PLANET, EarlyView.Goldenberry (Physalis peruviana) produces sweet, nutritionally rich berries, yet like many minor crops, is cultivated in limited geographical regions and has not been a focus of breeding programs for trait enhancement. Leveraging knowledge of plant architecture‐related traits from related species, we used CRISPR/Cas9‐mediated gene editing to generate a
Miguel Santo Domingo +8 more
wiley +1 more source
Transformers: African American Women Leaders in the Pharmaceutical Industry [PDF]
, 2016 This qualitative study documents the experiences of African American women leaders in the pharmaceutical industry in the context of the transformative leadership model. Transformative leadership is a theory that recognizes that the success of individuals
Bonaparte, Yvette Lynne
core +1 more source
International Journal for Equity in HealthObjective The accessibility issue of orphan drugs in China is prominent. Based on real-world data from a tier-one city in Northeast China, this study aims to analyze the current usage and affordability of orphan drugs for rare diseases.
Yaqun Wang +6 more
doaj +1 more source
Rheumatology &Autoimmunity, EarlyView.This observational study assessed the association between anti‐type 2 biologic agents and the occurrence of autoimmune diseases using a large real‐world claims database. Anti‐IL‐5 and anti‐IgE therapies were associated with an increased occurrence of autoimmune diseases, including rheumatoid arthritis (RA) and systemic lupus erythematosus (SLE ...
Shoichiro Inokuchi
wiley +1 more source
Orphan Drugs in Neurology-A Narrative Review. [PDF]
J Pers Med, 2023 Sirbu CA +7 more
europepmc +1 more source