Results 201 to 210 of about 88,754 (289)

A Retrospective Chart Review of the Prevalence, Characteristics, and Discharge Destinations of Patients Hospitalized as “Social Admissions”

Journal of the American Geriatrics Society, EarlyView.
Overview of study.
Jasmine Mah, Lucy Eum, Lindsey Puddicombe, Christie Stilwell, Karen Nicholls, Hamish Frayne, Clara Long, Kristin Ko, Victoria Howatt, Margaret Man‐Ger Sun, Lynnea Lobert, Gali Latariya, Katalin Koller, Susan Freter, Maia von Maltzahn, Kenneth Rockwood, Samuel D. Searle, Melissa K. Andrew   +17 more
wiley   +1 more source

Results of health technology assessments of orphan drugs in Germany-lack of added benefit, evidence gaps, and persisting unmet medical needs. [PDF]

Int J Technol Assess Health Care
Kranz P, McGauran N, Ünal C, Kaiser T.
europepmc   +1 more source

Variables affecting pricing of orphan drugs: the Italian case. [PDF]

Orphanet J Rare Dis, 2021
Jommi C, Listorti E, Villa F, Ghislandi S, Genazzani A, Cangini A, Trotta F.   +6 more
europepmc   +1 more source

Making the Old New Again Through the Process of Recombinant Innovation

Journal of Product Innovation Management, EarlyView.
ABSTRACT Academic Summary Recombinant innovation—the process through which atypical and unexpected combinations of knowledge generate novel outcomes—is a critical driver of organizational distinctiveness and market transformation. While prior research has focused on firm‐ and industry‐level mechanisms, less attention has been given to multilevel ...
Vittoria Magrelli, Josip Kotlar, Alfredo De Massis, Federico Frattini, Antonio Messeni Petruzzelli   +4 more
wiley   +1 more source

Orphan drugs: The final frontier in the fight against rare diseases.

Indian J Pharmacol
Rajaram S, Medhi B.
europepmc   +1 more source

Implementation status of pharmacological studies in the development of orphan drugs. [PDF]

Orphanet J Rare Dis
Yokoshiki S, Arato T.
europepmc   +1 more source

Narcolepsy and rapid eye movement sleep

Journal of Sleep Research, Volume 34, Issue 2, April 2025.
Summary Since the first description of narcolepsy at the end of the 19th Century, great progress has been made. The disease is nowadays distinguished as narcolepsy type 1 and type 2. In the 1960s, the discovery of rapid eye movement sleep at sleep onset led to improved understanding of core sleep‐related disease symptoms of the disease (excessive ...
Francesco Biscarini, Lucie Barateau, Fabio Pizza, Giuseppe Plazzi, Yves Dauvilliers   +4 more
wiley   +1 more source

Development of the Emirates Multi-Criteria Decision Analysis Tool for Orphan Drugs. [PDF]

Cureus
Alnaqbi KA, Elezbawy B, Fasseeh AN, Bangash AR, Elshamy A, Shendi H, Aftab MI, AlMarshoodi M, Gebran N, AlDhaheri N, Fahmy SA, Al Dallal S, Al Naeem W, Abaza S, Kaló Z.   +14 more
europepmc   +1 more source

Age at Onset and Delays in Diagnosis of Central Disorders of Hypersomnolence Over the Past 30 Years

Journal of Sleep Research, EarlyView.
ABSTRACT Patients with narcolepsy type 1 (NT1), type 2 (NT2), idiopathic hypersomnia (IH) usually suffer from symptoms for years, even decades, before being diagnosed. We aimed to assess age at onset, age at diagnosis and changes in the diagnostic delays of these patients from 1990 to 2020 in a single centre.
Zhongxing Zhang, Lucie Barateau, Séverine Béziat, Ramin Khatami, Yves Dauvilliers   +4 more
wiley   +1 more source

Lucid Dreaming: Not Just Awareness, but Agency

Journal of Sleep Research, EarlyView.
ABSTRACT During lucid dreaming (LD), dreamers are aware that they are dreaming and may be able to influence the oneiric content. There has been recent debate about the relative importance of the ability to influence the dream and having agency over the pure awareness of dreaming.
Severin Ableidinger, Luigi De Gennaro, Sergio Mota‐Rolim, Serena Scarpelli, Courtney J. Bolstad, Bjørn Bjorvatn, Colin A. Espie, Yves Dauvilliers, Maria Korman, Anne‐Marie Landtblom, Giuseppe Plazzi, Kentaro Matsui, Juliana Yordanova, Adrijana Koscec Bjelajac, Catia Reis, Frances Chung, Ilona Merikanto, Yun K. Wing, Markku Partinen, Tainá Macêdo, Michael R. Nadorff, Brigitte Holzinger   +21 more
wiley   +1 more source