Results 211 to 220 of about 88,754 (289)

Estimating the minimal cost of delivering nutrition‐specific and nutrition‐sensitive interventions in Ethiopia

Maternal &Child Nutrition, EarlyView.
The minimum cost of the 10 years on identified nutrition‐specific and nutrition‐sensitive interventions of the National Food and Nutrition Strategy in Ethiopia is estimated to be US$ 2.55bn with an average annual cost of $250 million over 10 years (2021–2030), which is only 2.3% of the Ethiopian Annual GDP 111.27 billion US dollars in 2021 (World bank).
Yetayesh Maru, Firehiwot Mesfin, Arnaud Laillou, Ramadhani Noor, Shiva Raj Adhikari, Meseret Zelalem, Hiwot Darsene, Solomon Memire, Andarge Abie, Stanley Chitekwe   +9 more
wiley   +1 more source

Higher Objectives of Islamic Law (Maqāṣid al‐Sharīʿa) in Substantiating Justice in Land Tax

The Muslim World, EarlyView.
Abstract This article discusses the relationship between the systemization of kharāj (land tax) and the higher objective of Islamic law or Maqāṣid al‐Sharīʿa. After the conquest of Sawād region (located in modern‐day southern Iraq), the First Caliph ʿUmar (634 ‐ 644 CE) introduced a new approach to the distribution of ghanīmah (spoils of war), leaving ...
Öznur Özdemir, Mehmet Asutay
wiley   +1 more source

Development of orphan drugs for rare diseases. [PDF]

Clin Exp Pediatr
Yoo HW.
europepmc   +1 more source

Estimating Correlations Between Clinical Trial Outcomes Using Generalised Estimating Equations

Oxford Bulletin of Economics and Statistics, EarlyView.
ABSTRACT Accurately estimating the correlations among clinical trial outcomes is crucial for managing the risk of biopharmaceutical investment portfolios. We propose a novel algorithm for estimating correlations in large clinical trial datasets using a generalised estimating equations (GEE) framework.
Yuehao Dai, Andrew W. Lo, Manish Singh, Qingyang Xu, Ruixun Zhang   +4 more
wiley   +1 more source

KRP3 Stability Controls Rice Plant Architecture and Productivity via MPK3‐Mediated Phosphorylation

Plant Biotechnology Journal, EarlyView.
ABSTRACT Yield is a critical agronomic trait in cereal crops, shaped by factors like tiller and seed number, and seed weight. Understanding the factors governing these traits will help in improving the yield of plants. In this study, we identified an orphan gene, KRP3, belonging to cereal crops as a key regulator of rice plant architecture.
Gopal Banerjee, Sarvesh Jonwal, Balakrishnan Rengasamy, Uttam Pal, Dhanraj Singh, Mohit Mohit, Alok Krishna Sinha   +6 more
wiley   +1 more source

Issues, Challenges and Opportunities for Economic Evaluations of Orphan Drugs in Rare Diseases: An Umbrella Review. [PDF]

Pharmacoeconomics
Grand TS, Ren S, Hall J, Åström DO, Regnier S, Thokala P.   +5 more
europepmc   +1 more source

Prolonged exposure to artificial light and carcinogenesis: A systematic review of oncostatic mechanisms associated with melatonin pathways

Photochemistry and Photobiology, EarlyView.
Exposure to artificial light at night (ALAN), particularly at blue wavelengths, disrupts circadian rhythms by suppressing melatonin, thereby increasing cancer susceptibility. This systematic review consolidates evidence linking prolonged ALAN exposure to an elevated risk of breast and prostate tumors.
Gabriel Barboza, Jêmina Oliveira, Antônio Ferreira, Renan Lopes, Marli Cupertino   +4 more
wiley   +1 more source

Availability and Access to Orphan Drugs for Rare Cancers in Bulgaria: Analysis of Delays and Public Expenditures. [PDF]

Cancers (Basel)
Kostadinov K, Popova-Sotirova I, Marinova Y, Musurlieva N, Iskrov G, Stefanov R.   +5 more
europepmc   +1 more source

Impacts of exercise, renin–angiotensin system modulation or both on skeletal muscle circadian gene expression

Experimental Physiology, EarlyView.
Abstract Ageing negatively affects quality of life and healthspan, and interventions are needed to slow this progressive decline. Previously, we have demonstrated the potential functional benefits of combining a genetically modified probiotic (GMP) targeting the non‐canonical arm of the renin–angiotensin system (RAS) with exercise training.
Emily L. Zumbro, Liliana C. Baptista, Taylor Taylor, Abbi R. Hernandez, Anisha Banerjee, Yi Sun, YouFeng Yang, Qiuhong Li, Thomas W. Buford   +8 more
wiley   +1 more source

Clinical aspects of reimbursement policies for orphan drugs in Central and Eastern European countries. [PDF]

Front Pharmacol
Jakubowski S, Kawalec P, Holko P, Kowalska-Bobko I, Kamusheva M, Petrova G, Draganić P, Fuksa L, Männik A, Ispán F, Briedis V, Bianchi I, Paveliu MS, Tesar T.   +13 more
europepmc   +1 more source