Results 191 to 200 of about 16,760 (259)

Enhancing Veterinary Education: Integrating Wildlife Medicine Into Undergraduate Training in Kenya. [PDF]

Vet Med Int
Watene G, Smith D, Abuom T, Kipyegon A, Lekolool I, Omani R, Scarlett M.   +6 more
europepmc   +1 more source

Novel approaches for drug development against chronic primary pain: A systematic review

British Journal of Pharmacology, EarlyView.
Abstract Chronic primary pain (CPP) persisting for more than 3 months, associated with significant emotional distress without any known underlying cause, is an unmet medical need. Traditional or adjuvant analgesics do not provide satisfactory pain relief for a great proportion of these patients.
Valéria Tékus, Éva Borbély, Andreas Goebel, Ralf Baron, Zsófia Hajna, Zsuzsanna Helyes   +5 more
wiley   +1 more source

Communication about sexuality for adolescents with cerebral palsy and complex communication needs: A scoping review with framework synthesis. [PDF]

Dev Med Child Neurol
Walsh M, Sawyer SM, Watson JM, O'Shea A, Cranko G, Pacheco CM, Pennacchia J, Anderson KLM.   +7 more
europepmc   +1 more source

Peripheral targets for neuropathic pain

British Journal of Pharmacology, EarlyView.
Neuropathic pain represents a significant clinical challenge, with still limited pharmacological approaches to symptomatic relief. This review focuses on molecular targets implicated in neuropathic pain, particularly those involved in peripheral mechanisms. Using the IUPHAR/BPS database of biological targets, their occurrence together with ‘neuropathic
Amirhossein Afsharipour, Cosmin I. Ciotu, Felix J. Resch, Michael J. M. Fischer   +3 more
wiley   +1 more source

Knowledge and practices of school teachers toward learning disabilities: An observational study in a district of Kerala, South India. [PDF]

J Family Med Prim Care
Sameena MN, Thasneem NB, Kaimal RS, Rajeev I.   +3 more
europepmc   +1 more source

Intestinal STING‐(Over)activation—A Contributing Factor to Food Allergies?

Allergy, EarlyView.
Sophie Goebel, Hannah Ruth Schiller
wiley   +1 more source

Systematic profiling reveals broad G protein coupling and context‐dependent modulation of cyclic AMP by the orphan receptor GPR139

British Journal of Pharmacology, EarlyView.
Background and Purpose G protein‐coupled receptors (GPCRs) are major drug targets, yet many orphan receptors remain poorly characterized. GPR139 has been implicated in CNS disorders, including schizophrenia and depression, but its signalling mechanisms remain unclear.
Boris Trapkov, Hans Bräuner, Alexander Sebastian Hauser   +2 more
wiley   +1 more source

Displaying Moral Courage in Providing Discretionary Treatment in a Technologically Advanced, yet Resource-Limited Setting. [PDF]

Asian Bioeth Rev
Abraham S, Ghosh U.
europepmc   +1 more source

Inhibition of the NR4A1‐mediated cell cycle checkpoint enhances hyperplastic adipogenesis and glucose homeostasis in obesity

British Journal of Pharmacology, EarlyView.
Abstract Background and Purpose The nuclear receptor NR4A1 is a critical node in transcriptional circuits for metabolic adaptation, yet its role in adipocyte progenitor (AP) fate and proliferation is unclear. We sought to define how NR4A1 governs early adipogenesis and adipose tissue plasticity.
Wanning Qiao, Cun Ku, G. V. Naveen Kumar, Jonathan D. Brown, Manni Wu, Chenhang Li, Jiyu Xie, Huicui Meng, Litao Sun, Tao Zhou, Dong Liang, Yiwei Li, Matthew L. Steinhauser, Yang Zhang   +13 more
wiley   +1 more source

Continuity of care should be Dr Ian McWhinney's lasting legacy: Part 4 of the 10-part series, "Foundations for tomorrow". [PDF]

Can Fam Physician
Heath I.
europepmc   +1 more source