Results 81 to 90 of about 63,288 (330)

PTSD from Childhood Trauma as a Precursor to Attachment Issues [PDF]

open access: yes, 2016
The past 20 years have been turbulent regarding Reactive Attachment Disorder (RAD), with conflicting research about its causes, effects, treatment, and prognosis. The current diagnostic criteria in the DSM-5 fails to adequately address this disorder.
Owen, Christy
core   +1 more source

Engineered GM1 Intersects Between Mitochondrial and Synaptic Pathways to Ameliorate ALS Pathology

open access: yesAdvanced Science, EarlyView.
Amyotrophic Lateral Sclerosis (ALS) is a fatal neurodegenerative disease driven by genetic and molecular disruptions affecting energy balance, protein homeostasis, and stress responses in nerve cells. Studies using human and rodent models identified convergent defects in mitochondria and synaptic function.
Federica Pilotto   +11 more
wiley   +1 more source

The coffee gene orphanage : S01P14 [PDF]

open access: yes, 2013
Coffee is a perennial crop considered one of the most important agricultural commodities in the world. By consequence, aiming at the establishment of tools to help accelerating the genetic improvement of this species, significant advances in coffee ...
Andrade, Alan Carvalho   +8 more
core  

The volunteer tourist as 'hero' [PDF]

open access: yes, 2010
Volunteer tourism is a rapidly growing form of tourism which has a weak conceptual basis and which is generally defined rather simply in terms of participants' actions while on holiday, ignoring elements such as reasons for participation, behaviour, and ...
Butler, Richard, Tomazos, Konstantinos
core   +1 more source

Spatiotemporal Organization of PTK7 Diffusion on Cell Surface Facilitates Tumor Invasion and Migration

open access: yesAdvanced Science, EarlyView.
The spatiotemporal dynamics of protein kinase diffusion govern cellular signaling and functions. Although vital for active receptors, the role of pseudokinase dynamics is unclear. Here, we use single‐molecule tracking to link faster diffusion of pseudokinase PTK7 to increased tumor cell invasion and migration.
Yaohua Li   +8 more
wiley   +1 more source

EXPERIENCE OF MEDICAL AND SOCIAL AID TO WOMEN, GOING TO LEAVE THEIR CHILD

open access: yesВопросы современной педиатрии, 2012
Experience of the work with women, who decided to leave their child, is shown in this article. Young mothers have lived under the children hospital temporarily until their family, social and other problems were solved.
A. Z. Farrakhov   +5 more
doaj   +1 more source

COLONIALISM TOWARDS CHINESE SOCIETY IN W. SOMERSET MAUGHAM’S THE PAINTED VEIL [PDF]

open access: yes, 2013
In this thesis, the writer is interested to analyze colonialism in William Somerset Maugham’s The Painted Veil. The purposes of the thesis are to analyze how the British colonization works during the cholera epidemic in China, to analyze how the response
Pramesti , Endah
core  

A Functionally Conserved Enhancer is Critical for PGC1A Expression and Thermogenesis in Brown Fat

open access: yesAdvanced Science, EarlyView.
An evolutionarily conserved enhancer controls PGC1A expression and thermogenic activation in brown adipose tissue. Integrative multi‐omics analyses identify two BAT‐specific enhancers, with PGC1A‐En1 functioning as the dominant regulatory element that maintains thermogenic capacity across species.
Duo Su   +10 more
wiley   +1 more source

Universal Antibody‐Engineered Lipid Nanoparticles Potentiate Chemo‐Immunotherapy Against Triple‐Negative Breast Cancer by Reprogramming Tumor Cell Metabolism

open access: yesAdvanced Science, EarlyView.
A universal ROR1 antibody‐engineered lipid nanoparticle (LNP) is constructed by sequential drug encapsulation and antibody conjugation. The LNP not only enables enhanced chemotherapeutic efficiency by targeting drug delivery and precise localization of deep‐seated tumors through NIR‐II fluorescence imaging, but also remodels immunosuppressive TME ...
Yeneng Dai   +12 more
wiley   +1 more source

Risiko Masalah Perkembangan dan Mental Emosional Anak yang Diasuh di Panti Asuhan Dibandingkan dengan Diasuh Orangtua Kandung

open access: yesMajalah Kedokteran Bandung, 2014
Children living in orphanage are associated with delays in development. The children demostrate less developmental problems when they interact with caregivers.
Riyadi   +2 more
doaj   +1 more source

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