Results 81 to 90 of about 16,760 (259)
Clinical Pharmacology &Therapeutics, EarlyView.When setting the price of cell and gene therapies in Japan, the factors considered include the manufacturing and operating costs of the new drug or a comparator, leading to discrepancies between price and values, in particular those specific to cell and gene therapies.
Akina Takami, Ataru Igarashi
wiley +1 more source
Child and Adolescent Psychiatry and Mental Health, 2011 Background The number of orphans in Sub-Saharan Africa is constantly rising. While it is known that family or community care is preferable over institutional care of African orphans, little is known about the quality of care in orphanages and ...
Schauer Elisabeth +5 more
doaj +1 more source
Annual report of the managers of the Church of England Orphanage, 1950-1951
, 1950 The annual report of the Church of England orphanage in St.
Church of England Orphanage (St. John's, N.L.)
core
Long‐Acting Therapeutics in Pediatric Health: Bridging Innovation and Access
Clinical Pharmacology &Therapeutics, EarlyView.Children have distinct therapeutic needs arising from age‐dependent physiology, disease epidemiology, formulation requirements, dosing considerations, and safety vulnerabilities. Despite substantial reductions in childhood mortality over the past three decades, nearly 5 million children under five died in 2023, with infectious diseases continuing to ...
Prajith Venkatasubramanian +5 more
wiley +1 more source
Annual report of the managers of the Church of England Orphanage, 1932
, 1932 The annual report of the Church of England orphanage in St.
Church of England Orphanage (St. John's, N.L.)
core
Transcriptomic Profiling of SLC and ABC Transporters in the Human Term Placenta
Clinical Pharmacology &Therapeutics, EarlyView.Solute carriers (SLC) and ATP‐binding cassette (ABC) transporters are essential for placental solute exchange and fetal protection, yet their transcriptomic profiles in the human placenta remain poorly characterized. Although fetal sex influences placental development and function, its impact on transporter expression is unclear.
Elijah Marsh Jung +12 more
wiley +1 more source
, 2021 Orphanage trafficking is defined as the recruitment or transfer of children to residential care institutions, for a purpose of exploitation and/or profit.
van Doore, Kathryn, Nhep, Rebecca
core
Clinical Pharmacology &Therapeutics, EarlyView.Evidence on the efficacy and safety of medicines supporting marketing authorization is largely derived from randomized controlled trials, yet these trials often exclude populations likely to use the medications in clinical practice. This study assessed eligibility of special populations, defined as pregnant and breast‐feeding individuals, elderly ...
Maja J. Jørgensen +2 more
wiley +1 more source
Clinical Pharmacology &Therapeutics, EarlyView.Anakinra, an interleukin‐1 receptor antagonist, shows promise for reducing inflammatory complications of premature birth. However, the pharmacokinetics (PK) of anakinra in neonates has not been characterized, limiting evidence‐based dosing. This study aimed to develop a population PK model for anakinra to guide dosing in preterm neonates.
Jia Li +27 more
wiley +1 more source
INCIDENCE OF PEDIATRIC URINARY STONES IN ORPHANAGE CHILDREN IN PEKANBARU, RIAU PROVINCE OF INDONESIA
National Journal of Medical Research, 2018 Introduction: Urinary stones are seldom in children. Currently the incidence of urinary stones in children increases three time folds in the last third decade and occurs in the first decade of life.
Zuhirman Zamzami
doaj