Results 61 to 70 of about 553 (184)
ABSTRACT The article examines the history of phonographic recordings from the Jesup North Pacific Expedition (1897–1902), a venture that shaped the methods of Siberian and Arctic anthropology for decades. The authors—a historical anthropologist, a curator, and an Indigenous Sakha scholar—trace how audio recordings made during the expedition have moved ...
Dmitry Arzyutov +2 more
wiley +1 more source
Abstract Microbes produce bioactive secondary metabolites as toxins, pigments, or virulence factors. These specialized compounds are produced by nonribosomal peptide synthetases (NRPS), polyketide synthases (PKS), or hybrid NRPS/PKS pathways. The genes encoding NRPS and PKS reside in biosynthetic gene clusters (BGCs), some of which have no identified ...
Amaan M. Fruitwala +4 more
wiley +1 more source
Medications That Regulate Pregnane X Receptor: A Systematic Review of Current Evidence
PRISMA 2020 flow diagram of study selection for this systematic review of medications that regulate the pregnane X receptor (PXR), from 12 236 records screened to 101 included studies. ABSTRACT The pregnane X receptor (PXR) gene encodes a ligand‐activated protein involved with the metabolism and excretion of drugs, toxins, and other xenobiotics.
Petra Czarniak +4 more
wiley +1 more source
This thesis considers the colonial literary relationship between the centre and the margin in the field of post-colonial counter-discourse. As such, this thesis investigates the possibility of disrupting the dominance of Empire, which is often rhetorically constructed through the certainty of the parent and child binary relationship.
openaire +2 more sources
ABSTRACT In just a few decades, historiography on gender and law in Latin America has grown from foundational works establishing the dimensions of women's legal status in colonial compilations and later national codes to scholarship that considers the distinctions among different social groups of women and traces women as active agents in pluralistic ...
Sarah C. Chambers
wiley +1 more source
ABSTRACT The dual‐species biofilms formed by Streptococcus mutans and Candida albicans exhibit enhanced cariogenic potential due to the production of extracellular polysaccharides (EPSs). The response regulator GcrR in S. mutans negatively regulates EPS synthesis, but its impact on dual‐species biofilms remains unclear.
Bin Zhang +7 more
wiley +1 more source
ABSTRACT Background & Aims: Cancer‐associated fibroblasts (CAFs) drive immunosuppression in hepatocellular carcinoma (HCC). However, their metabolic regulation remains poorly defined. We investigated the role of nicotinamide N‐methyltransferase (NNMT) in CAFs. Approach & Results: High NNMT expression in CAF tissues was confirmed by western blotting and
Shounan Lu +20 more
wiley +1 more source
Early Trauma Leaves No Social Signature in Sanctuary-Housed Chimpanzees (Pan troglodytes). [PDF]
van Leeuwen EJC +2 more
europepmc +1 more source
Scutellarein alleviates ulcerative colitis by reinforcing the intestinal barrier via the microbiota‐metabolite axis and suppressing PRMT1‐STAT3‐mediated inflammatory immune responses. ABSTRACT Ulcerative colitis (UC) is a chronic inflammatory disease of the colonic mucosa with an increasing global burden and limited therapeutic efficacy.
Yefan Zhou +12 more
wiley +1 more source

