Results 91 to 100 of about 640 (257)

Resolution of Levodopa/Dopa‐Decarboxylase Inhibitor—Associated Microscopic Colitis with Subcutaneous Foslevodopa/Foscarbidopa: A Case Series and Review of the Literature

open access: yesMovement Disorders Clinical Practice, EarlyView.
Abstract Background Microscopic colitis (MC) typically presents with chronic, non‐bloody watery diarrhea. Diagnosis requires endoscopy with colonic mucosal biopsies. The etiology is multifactorial, with several medications implicated, although only a few cases have been attributed to oral levodopa/dopa‐decarboxylase inhibitor (LDDCI) therapy.
Romana Hintner   +10 more
wiley   +1 more source

Cardiac MIBG Scintigraphy in Neurodegenerative Parkinsonism: Limitations in Clinical Practice

open access: yesMovement Disorders Clinical Practice, EarlyView.
Abstract Background Reduced cardiac uptake on 123Iodine‐metaiodobenzylguanidine (MIBG) scintigraphy is a valuable tool for differentiating neurodegenerative parkinsonism but interpretation can be difficult due to comorbidities and drug‐tracer interactions.
Frank Jagusch   +9 more
wiley   +1 more source

Systematic Review of the Huntington's Disease Drug Development Pipeline, 2014 to 2025

open access: yesMovement Disorders, EarlyView.
Abstract Background In the past decade, significant advances have improved our understanding of the mechanisms underlying HD pathobiology leading to several putative therapeutic targets for HD. Objective The aim was to describe the Huntington's disease (HD) drug development clinical pipeline.
Pavlina Konstantinova   +5 more
wiley   +1 more source

Supplementary Figure 2

open access: yes
This is Supplementary Figure 2 for the manuscript "Orphaning stunts growth in wild African elephants" (currently under review), showing the top model fit with a density plot of the data (y) in black overlaying 10,000 simulated data sets (y_rep) according
Parker, Jenna
core   +1 more source

Small‐Molecule Kinase Inhibitors Modulating Circadian Rhythms

open access: yesMedicinal Research Reviews, EarlyView.
ABSTRACT The circadian clock mechanism generates 24‐h rhythms crucial for regulating various physiological processes, and its dysregulation has been implicated in numerous diseases. In cells, the circadian clock operates through a transcriptional‐translational feedback loop, where phosphorylation plays a pivotal role in maintaining accurate circadian ...
Irene Castellino   +3 more
wiley   +1 more source

Utah Orphaned and Plugged/Abandoned Oil and Gas Wells

open access: yes
A collection of orphaned or plugged and abandoned wells within the state of Utah on state, federal, and private land. Additional data collection has been done to include proximity to sensitive areas (protected lands, water, and census locations ...
Parson, Maxwell
core   +1 more source

Governing the Third Sector in the Gulf: A Systematic Review of Emergence, Capacity, and Policy Dynamics in Qatar, Saudi Arabia, Kuwait, and Oman

open access: yesPublic Administration and Development, EarlyView.
ABSTRACT The third sector has emerged as an increasingly important actor in governance, social development, and public service delivery across the Gulf Cooperation Council (GCC), yet scholarly understanding of its evolution, institutional capacity, and policy role remains fragmented and uneven.
Moosa Elayah   +2 more
wiley   +1 more source

Engineering compact Physalis peruviana (goldenberry) to promote its potential as a global crop

open access: yesPLANTS, PEOPLE, PLANET, EarlyView.
Goldenberry (Physalis peruviana) produces sweet, nutritionally rich berries, yet like many minor crops, is cultivated in limited geographical regions and has not been a focus of breeding programs for trait enhancement. Leveraging knowledge of plant architecture‐related traits from related species, we used CRISPR/Cas9‐mediated gene editing to generate a
Miguel Santo Domingo   +8 more
wiley   +1 more source

Efficient Methods for Rearing Strong Bee Queens

open access: yes, 2017
The aim was to choose the most efficient method to rear genetically strong queens: by overcrowding swarm or by orphaning the bees. The experiment was conducted in a private apiary in Teleorman County, between April and September 2015.
Monica Parvu   +3 more
core  

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