Results 21 to 30 of about 91,896 (245)

Targeted Photodynamic Therapy: A Novel Approach to Abolition of Human Cancer Stem Cells

International Journal of Optics, 2018
Cancer is a global burden that has prompted extensive research into prevention and treatment, over many decades. Scientific studies have shown that subset of cells within a tumour, known as cancer stem cells (CSCs), are responsible for tumourigenesis ...
Anine Crous, Elvin Chizenga, Natasha Hodgkinson, Heidi Abrahamse   +3 more
doaj   +1 more source

The hospital environment versus carriage: transmission pathways for third-generation cephalosporin-resistant bacteria in blood in neonates in a low-resource country healthcare setting

Scientific Reports, 2022
Neonatal bloodstream infections (BSI) can lead to sepsis, with high morbidity and mortality, particularly in low-income settings. The high prevalence of third-generation cephalosporin-resistant organisms (3GC-RO) complicates the management of BSI ...
Dory Kovacs, Vitus Silago, Delfina R. Msanga, Stephen E. Mshana, Jeremiah Seni, Katarina Oravcova, Louise Matthews   +6 more
doaj   +1 more source

Unrevealing the Impact of Annealing Condition on Catalytic Activity of PtNi Alloy Electrode Towards Oxygen Reduction Reaction

Indonesian Journal of Chemistry
Alloying platinum (Pt) with transition metals such as nickel (Ni) has been an effective approach for reducing Pt loading and enhancing catalytic activities towards the sluggish oxygen reduction reaction (ORR) on the cathode of proton exchange membrane ...
Anindya Pramudya Wardhani, Salwaa Tanaya, Retna Deca Pravitasari, Damisih Damisih, Dewi Kusuma Arti, Sri Rahayu, Muhammad Didik Gumelar, Elok Fidiani   +7 more
doaj   +1 more source

The Efficacy and Safety of Bevacizumab/Irinotecan/Temozolomide (BIT) for Relapsed/Refractory Neuroblastoma: The UK Children's Cancer and Leukaemia Group Experience

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Patients with high‐risk neuroblastoma who either are refractory to induction chemotherapy or relapse following multi‐modal treatment have a dismal prognosis. Based on data from the BEACON trial, since 2021 the UK national guidelines recommend bevacizumab, irinotecan, and temozolomide (BIT) for patients with relapsed/refractory ...
Thomas J. Jackson, Menna Shamma, Upeka Senanayake, Shaimaa Sahmoud, Kathleen Duffin, Victoria Howard, David King, Ayesha Fathani, Blanche Lumb, Andrei Pobischan, Irum Latif Memon, Monzir Ahmed, Rhian Thomas, Gerard Millen, Yasmeen Alomari, Sucheta Vaidya, Lynley V. Marshall, Sally L. George, Ramya Ramanujachar, Juliet Gray, Paola Angelini   +20 more
wiley   +1 more source

Density functional theory study of active sites on nitrogen-doped graphene for oxygen reduction reaction

Royal Society Open Science, 2021
Oxygen reduction reaction (ORR) remains challenging due to its complexity and slow kinetics. In particular, Pt-based catalysts which possess outstanding ORR activity are limited in application with high cost and ease of poisoning.
Ping Yan, Song Shu, Longhua Zou, Yongjun Liu, Jianjun Li, Fusheng Wei   +5 more
doaj   +1 more source

Alveolar Soft Part Sarcoma in Pediatric and Young Adult Patients: A Report From the Children's Oncology Group Study ARST0332

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Alveolar soft part sarcoma (ASPS) is a rare soft tissue sarcoma occurring most commonly in adolescence and young adulthood. Methods We present the clinical characteristics, treatments, and outcomes of patients with newly diagnosed ASPS enrolled on the Children's Oncology Group study ARST0332.
Jacquelyn N. Crane, Wei Xue, Amira Qumseya, Thomas Scharschmidt, Kathryn R. Tringale, Oscar Lopez Nunez, Jiaqi Hu, Donald A. Barkauskas, Rajkumar Venkatramani, Sheri L. Spunt, Aaron R. Weiss, Noah C. Federman   +11 more
wiley   +1 more source

Single/dual-metal active-site oxides for rechargeable zinc-air batteries: Fundamental properties, advancements, challenges, and future perspectives

Carbon Future
Rechargeable zinc-air batteries (RZABs) are considered one of the most promising candidates for advanced energy storage and conversion in the near future.
Yunrui Li, Ping Zhu, Fan Lan, Run Li, Ya Huang, Rufan Zhang   +5 more
doaj   +1 more source

Tumor‐stromal crosstalk and macrophage enrichment are associated with chemotherapy response in bladder cancer

FEBS Open Bio, EarlyView.
Chemoresistance in bladder cancer: Macrophage recruitment associated with CXCL1, CXCL5 and CXCL8 expression is characteristic of Gemcitabine/Cisplatin (Gem/Cis) Non‐Responder tumors (right side) while Responder tumors did not show substantial tumor‐stromal crosstalk (left side). All biological icons are attributed to Bioicons: carcinoma, cancerous‐cell‐
Sophie Leypold, Janik Riese, Lancelot Seillier, Mark Kühnel, Julia Pannhausen, Charlotte O. J. Fröhlich, Christian Martin, Peter Boor, Matthias Saar, Danny D. Jonigk, Nadine T. Gaisa, Michael Rose   +11 more
wiley   +1 more source

Enhancing Oxygen Reduction Reaction Activity on Pt/C Catalysts for PEFCs Using Phosphonium Ionic Liquid Layers: Effects of Proton Introduction and Physicochemical Properties

Electrochemistry
Polymer electrolyte fuel cells (PEFCs) have attracted significant attention as clean energy conversion systems. Pt nanoparticles are commonly used as cathode catalysts in PEFCs due to their high activity for the oxygen reduction reaction (ORR).
Hirohisa YAMADA, Takuya OKADA, Mitsuhiro MATSUMOTO, Yu YAO, Uta ANDO, Yuri OI, Toshikazu HIGASHI, Yohtaro INOUE, Katsuhiko TSUNASHIMA   +8 more
doaj   +1 more source

Integrating Patient‐Reported Quality Measures in SLE: Development of the American College of Rheumatology Implementation Guide

Arthritis Care &Research, Accepted Article.
Objective To support high‐quality, patient‐centered care for systemic lupus erythematosus (SLE), the American College of Rheumatology (ACR) developed evidence‐based measures incorporating clinical and patient‐reported outcomes measures (PROMs). Using the Consolidated Framework for Implementation Research (CFIR), we conducted semi‐structured interviews ...
Catherine Nasrallah, Cherish Wilson, Christine Hariz, Christie M Bartels, Shanthini Kasturi, Wambui Machua, Amy Bennett, Kate Chiseri, Allison Plitman, Starla Hairston Blanks, April Jorge, Patti Katz, Jinoos Yazdany, Shivani Garg   +13 more
wiley   +1 more source