Results 41 to 50 of about 663 (117)

Tirbanibulin (KX2‐391) analog KX2‐361 inhibits botulinum neurotoxin serotype A mediated SNAP‐25 cleavage in pre‐ and post‐intoxication models in cells

open access: yesDrug Development Research, Volume 85, Issue 6, September 2024.
Abstract Botulinum neurotoxins (BoNT) inhibit neuroexocytosis, leading to the potentially lethal disease botulism. BoNT serotype A is responsible for most human botulism cases, and there are no approved therapeutics to treat already intoxicated patients. A growing body of research has demonstrated that BoNT/A can escape into the central nervous system,
Dilara Koc   +4 more
wiley   +1 more source

Post‐Transcriptional Regulation of Rab7a in Lysosomal Positioning and Drug Resistance in Nutrient‐Limited Cancer Cells

open access: yesTraffic, Volume 25, Issue 9, September 2024.
ABSTRACT Limited nutrient availability in the tumor microenvironment can cause the rewiring of signaling and metabolic networks to confer cancer cells with survival advantages. We show here that the limitation of glucose, glutamine and serum from the culture medium resulted in the survival of a population of cancer cells with high viability and ...
Aliye Ezgi Güleç Taşkıran   +12 more
wiley   +1 more source

Effect of fibers on starch structural changes during hydrothermal treatment: multiscale analyses, and evaluation of dilution effects on starch digestibility

open access: yesJournal of the Science of Food and Agriculture, Volume 104, Issue 10, Page 5724-5734, 15 August 2024.
Abstract BACKGROUND Dietary fibers (DFs) may influence the structural, nutritional and techno‐functional properties of starch within food systems. Moreover, DFs have favorable effects on the digestive system and potentially a lower glycemic index. These potential benefits may change depending on DF type.
Özge Güven, İlkay Şensoy
wiley   +1 more source

A Comparison of Item- and Context-Noise Models in Recognition Memory

open access: yesAnkara Üniversitesi Dil ve Tarih-Coğrafya Fakültesi Dergisi, 2018
Item-noise models (b; Shiffrin and Steyvers 145-166) assert that recognition memory performance depends on item information of other traces in the list.
Sinem AYTAÇ, Aslı KILIÇ
doaj   +1 more source

Utilization of cross‐correlation function for assessment of replication quality in ultrasonic embossing of microchannels on polymethyl methacrylate

open access: yesPolymer Engineering &Science, Volume 64, Issue 7, Page 3227-3242, July 2024.
Ultrasonic embossing of microchannels and assessment of replication quality by cross‐correlating the derivatives of the profiles of the embossed microchannel profile and the mold. Abstract Ultrasonic embossing—a process where a horn vibrating at 20–30 kHz compresses on a thermoplastic substrate sitting on a mold to replicate the features on the mold to
Ender Yildirim   +2 more
wiley   +1 more source

Impact of Graduating with Honours on Entry Wages of Economics Majors*

open access: yesOxford Bulletin of Economics and Statistics, Volume 86, Issue 3, Page 606-640, June 2024.
Employers use various proxies to predict the future labour productivity levels of the job applicants. Success in school, especially in high‐level coursework, is among the most widely used proxies to screen entry‐level candidates. We estimate the causal effect of graduating with honours (i.e.
Salim Atay, Gunes A. Asik, Semih Tumen
wiley   +1 more source

Source Memory: A Review

open access: yesAnkara Üniversitesi Dil ve Tarih-Coğrafya Fakültesi Dergisi, 2018
Memory records include different kinds of information representing from whom, how, where and when those records were obtained. Source monitoring is an attribution process of memories to their origins. This monitoring is also required for discriminating a
Hilal TANYAŞ, Mine MISIRLISOY
doaj   +1 more source

Gallic acid crosslinked peanut protein‐corn starch composite edible films produced at alkaline pH with ultrasound application

open access: yesJournal of Applied Polymer Science, Volume 141, Issue 18, May 10, 2024.
The effects of gallic acid addition and high‐intensity ultrasound on physicochemical properties of the peanut protein‐corn starch films. Abstract Corn starch and peanut protein blend films were prepared with and without gallic acid addition (0.25%, w/v) at pH 7, 9, and 11 by casting.
Kubra Ertan, Serpil Sahin, Gulum Sumnu
wiley   +1 more source

A partial epithelial‐mesenchymal transition signature for highly aggressive colorectal cancer cells that survive under nutrient restriction

open access: yesThe Journal of Pathology, Volume 262, Issue 3, Page 347-361, March 2024.
Abstract Partial epithelial‐mesenchymal transition (p‐EMT) has recently been identified as a hybrid state consisting of cells with both epithelial and mesenchymal characteristics and is associated with the migration, metastasis, and chemoresistance of cancer cells.
Gil A Pastorino   +18 more
wiley   +1 more source

SETD3 regulates endoderm differentiation of mouse embryonic stem cells through canonical Wnt signaling pathway

open access: yesThe FASEB Journal, Volume 38, Issue 4, 29 February 2024.
In wild‐type mouse embryonic stem cells, the SET‐domain methyltransferase SETD3 interacts with β‐catenin, sustaining the canonical Wnt signaling pathway‐related gene expression, eventually leading to successful meso/endodermal lineage commitment. The deletion of Setd3 from mouse embryonic stem cells leads to changes in the activity of various signaling
Ceren Alganatay   +4 more
wiley   +1 more source

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