Results 81 to 90 of about 1,617 (180)

Clinical Outcomes Following Intra-Articular Administration of Autologous Muscle-Derived Mesenchymal Stem Cells in Horses with Chronic Osteoarthritis: A Prospective Open-Label Study

Animals
Mesenchymal stromal/stem cells (MSCs) are increasingly investigated as intra-articular therapies for equine osteoarthritis (OA), although most studies have focused on allogeneic or combination-based approaches.
Didier Serteyn, Hélène Graide, Justine Ceusters, Maxime Vandersmissen, Alexandra Salciccia, Charlotte Sandersen, Jean-Philippe Lejeune   +6 more
doaj   +1 more source

Platelet-Rich Plasma: Mechanotransduction, Tissue Loading, and Regenerative Repair for Pain Medicine

Biophysica
Musculoskeletal pain is driven by degenerative conditions such as osteoarthritis or intervertebral disk degeneration. This creates a major burden on health systems and patient quality of life.
Ahmed I. Anwar, Josephine M. Feeney, Joseph B. Delaney, Christopher L. Robinson, Jamal Hasoon, Alan D. Kaye   +5 more
doaj   +1 more source

Preparing the soil in knee osteoarthritis: a seed–systemic soil–local tissue soil framework for orthobiologic response heterogeneity

Frontiers in Bioengineering and Biotechnology
Musculoskeletal regenerative medicine has traditionally been guided by a product-centered model in which therapeutic outcomes are primarily attributed to the biological characteristics of the administered orthobiologic. However, the marked variability in
Joelington Dias Batista, Ludimila Dias Silva, Jobson Dias Batista, Gabrielly Santos Pereira, Marcelo Silva   +4 more
doaj   +1 more source

Platelet-Rich Plasma in Equine Osteoarthritis: A Systematic Review of Clinical and Experimental Evidence

Animals
Osteoarthritis (OA) is a major cause of equine lameness, with few effective disease-modifying treatments. This systematic review, conducted following the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines, evaluated ...
Jorge U. Carmona, Catalina López
doaj   +1 more source

Enhancing Cartilage Repair: Surgical Approaches, Orthobiologics, and the Promise of Exosomes

Treating cartilage damage is challenging as its ability for self-regeneration is limited. Left untreated, it can progress to osteoarthritis (OA), a joint disorder characterized by the deterioration of articular cartilage and other joint tissues. Surgical
Jonathan Layne, Johnny Huard, Jacob Singer, Noah Knezic, Jeff Christiansen, Greta Gohring, Ben Rothrauff   +6 more
core   +1 more source

An International Expert Consensus Statement Defining the Best Practices and Areas of Uncertainty Concerning the Use of Orthobiologics

Background: The use of orthobiologics has received increasing interest given the potential positive treatment effects on symptoms and tissue regeneration. However, there remains substantial variability surrounding
Cameron Gerhold, Kyle N. Kunze, Jacob T. Morgan, the Delphi Study Group, Nicolas S. Piuzzi, Tanner Nishioka, Jorge Chahla   +6 more
core   +1 more source

Micro‐fragmented adipose tissue for the treatment of hip osteoarthritis: A prospective pilot study at 1‐year follow‐up

Journal of Experimental Orthopaedics
Purpose Micro‐fragmented adipose tissue (MFAT) has been proposed as a promising option for hip osteoarthritis (OA). The aim of this prospective study was to evaluate clinical outcomes of MFAT injections in patients with hip OA.
Marco Zaffagnini, Federico Raggi, Eleonora Carillo, Luca Andriolo, Angelo Boffa, Carola Cavallo, Luca Cattini, Stefano Zaffagnini, Giuseppe Filardo   +8 more
doaj   +1 more source

Orthobiologics Injection Therapies in the Treatment of Muscle and Tendon Disorders in Athletes: Fact or Fake?

Muscle and tendon injuries encompass a wide range of conditions, including both acute and chronic ailments, and are common among athletes, representing a significant cause of injuries in various sports.
Vecchiato, Marco, Marchini, Andrea, Maffulli, Nicola, Gnasso, Rossana, Buttinoni, Leopoldo, Belviso, Immacolata, Frizziero, Antonio, Vascellari, Alberto, Vittadini, Filippo, Oliva, Francesco, Zappia, Marcello, Sirico, Felice, Tarantino, Domiziano, Palermi, Stefano, Corsini, Alessandro, Demeco, Andrea   +15 more
core   +1 more source

Treatment of knee cartilage lesions in 2024: From hyaluronic acid to regenerative medicine

Journal of Experimental Orthopaedics
Intact articular cartilage plays a vital role in joint homeostasis. Local cartilage repairs, where defects in the cartilage matrix are filled in and sealed to congruity, are therefore important treatments to restore a joint equilibrium.
Mats Brittberg
doaj   +1 more source

Editorial: Rising stars in veterinary regenerative medicine: 2022

Frontiers in Veterinary Science, 2023
Laura Barrachina, Janina Burk, Iris Gerner   +2 more
doaj   +1 more source