Results 91 to 100 of about 122,515 (169)

A Programmed DNA Dynamic Assembly‐Guided Molecular Amplifier for Authentic Information Decryption

Advanced Science, EarlyView.
This study presents a DNA‐based constitutional dynamic network (CDN) with adaptive thresholds for secure information decryption. The system self‐calibrates output patterns, ensuring reproducibility and accuracy, and integrates molecular amplifiers for expanded message capacity and precise DNA sensing.
Ning Yang, Jie Zhou, Fengying Yuan, Yajuan Liu, Jia Zhang, Ying Zhuo, Yu Ouyang, Yaqin Chai, Pu Zhang, Ruo Yuan   +9 more
wiley   +1 more source

Isolation Techniques of Micro/Nano‐Scaled Species for Biomedical Applications

Advanced Science, EarlyView.
Separating micro/nano‐scale bioparticles from samples is essential for disease diagnosis, prevention, and monitoring. Therefore, a comprehensive overview of the latest advanced separation technologies is provided, and characteristics and limitations based on six key performance parameters, including purity, recovery rate, throughput, resolution, size ...
Qing Lu, Zhinan Zhang, Xianting Ding
wiley   +1 more source

Split‐Aperture Xolography – Linear Volumetric Photoactivation with Short Axial Dimension and Low out of Focus Excitation

Advanced Science, EarlyView.
Stepwise excitation of dual‐color responsive molecules in a novel intersecting half‐cone geometry provides excellent spatial resolution while retaining the high efficiency and thus speed of the overall process. The approach provides volumetric methods with an enhanced performance at the nanoscale.
Martin Regehly, Stefan Hecht
wiley   +1 more source

Model‐Guided Rational Construction of Escherichia coli Synthetic Consortia for Enhanced 2‐Methylbutyric Acid Production

Advanced Science, EarlyView.
We developed a citramalate‐derived pathway for 2‐methylbutyric acid production in E. coli mono‐culture and consortia. The optimized consortium, using 2‐keto‐3‐methylvalerate as a node, achieved 1817.03 ± 103.73 mg L−1 2‐methylbutyric acid, a 28‐fold increase from the initial strain, with a yield of 0.091 g/g glucose.
Yu Liu, Boyuan Xue, Shaojie Wang, Haijia Su   +3 more
wiley   +1 more source

A Self‐Assembling LYTAC Mediates CTGF Degradation and Remodels Inflammatory Tumor Microenvironment for Triple‐Negative Breast Cancer Therapy

Advanced Science, EarlyView.
A CTGF‐LYTAC nanoplatform is developed to selectively degrade connective tissue growth factor (CTGF) in triple‐negative breast cancer (TNBC), inhibiting TGF‐β signaling and cell interactions in the tumor microenvironment (TME). This strategy effectively suppresses tumor growth and metastasis, outperforming antibody‐based therapy.
Jia‐Yi Lin, Ye Wu, Xiao‐Hui Liang, Min Tang, Xin Sun, Sheng‐Xin Lu, Jin‐Mei Jin, Xin Guo, Bei Wang, Hong‐Zhuan Chen, Wei‐Dong Zhang, Xin Luan   +11 more
wiley   +1 more source

Energy Dispersion Induced Precisely Tunable Friction of Graphitic Interface

Advanced Science, EarlyView.
This study introduces a novel approach to precisely tune nanoscale friction on monolayer graphene using coupled DC/AC electric fields. Combining experiments (contact‐mode electrostatic force microscopy) and simulations (generalized Prandtl–Tomlinson model), vertical resonance is shown to disperse horizontal energy, reducing friction while preserving ...
Zhao Liu, Hang Yang, Sen Wang, Jinxiong Wu, Wengen Ouyang, Junyan Zhang, Feng Luo   +6 more
wiley   +1 more source

Single‐Pixel Infrared Miniaturized Spectrometer Enabled by Ultra‐Broadband Reconfigurable Photodetection

Advanced Science, EarlyView.
A near‐infrared tunable micro‐spectrometer is achieved by integrating a PbS photodetection unit and a light modulation unit based on liquid crystal tuned optical resonances, demonstrating a wavelength tuning range exceeding 850 nm. This micro‐spectrometer shows high fidelity in spectral reconstruction and is also successfully applied to plastic sorting,
Wenyue Liang, Xianghong Nan, Wenfeng Cai, Ning Tan, Qilin Zheng, Yuyao Lu, Yongyue Huang, Jiahao Yan, Dangyuan Lei, Long Wen, Yanjun Liu, Qin Chen   +11 more
wiley   +1 more source

Neutrophil Macrophage Crosstalk via Extracellular Vesicles Drives Reverse Migration in a Fully Human Model of Wound Healing

Advanced Science, EarlyView.
A novel microphysiological system that can mimic sterile or non‐sterile injury demonstrates that macrophage‐derived extracellular vesicles modulate neutrophil migratory responses to these different wound states. The model showed that resolution of inflammation through neutrophil reverse migration is driven by IL‐8 derived from extracellular vesicles ...
Kehinde Adebayo Babatunde, Oluwadamilola Fatimat Babatunde, Adeel Ahmed, Wilmara Salgado‐Pabon, David J Beebe, Sheena C. Kerr   +5 more
wiley   +1 more source

Generation of Neural Organoids and Their Application in Disease Modeling and Regenerative Medicine

Advanced Science, EarlyView.
Neural organoids provide a versatile platform for neurological research. Advances in organoid technology have partially achieved human neural tissue complexity in terms of tissue structure, cell diversity, and neural signaling, offering insights into neural disorders and regenerative strategies. Technology advances from biomaterials, bio‐manufacturing,
Ruiqi Huang, Feng Gao, Liqun Yu, Haokun Chen, Rongrong Zhu   +4 more
wiley   +1 more source

Robust Direction of Arrival and Polarization Parameter Estimation in Mutual Coupling Scenario with Non-Collocated Crossed Dipole Arrays. [PDF]

Sensors (Basel)
Chen W, Lan X, Wang X.
europepmc   +1 more source