Results 161 to 170 of about 132,686 (287)

Endoplasmic Reticulum Geometry Dictates Neuronal Bursting via Calcium Store Refill Rates and Exposes Selective Neuronal Vulnerability

open access: yesAdvanced Science, EarlyView.
The ER's continuous tubular network is maintained by ER‐shaping proteins whose mutation or dysregulation contributes to neurodegenerative diseases. Here, we show that ER morphology sets the speed of Ca2+ store replenishment between firing events. Disrupting ER continuity slows intra‐ER Ca2+ redistribution from extracellular refill (SOCE) sites, driving
Valentina Davi   +13 more
wiley   +1 more source

Atomic Defects in Layered Transition Metal Dichalcogenides for Sustainable Energy Storage and the Intelligent Trends in Data Analytics

open access: yesAdvanced Science, EarlyView.
This review comprehensively summarizes the atomic defects in TMDs for their applications in sustainable energy storage devices, along with the latest progress in ML methodologies for high‐throughput TEM data analysis, offering insights on how ML‐empowered microscopy facilitates bridging structure–property correlation and inspires knowledge for precise ...
Zheng Luo   +6 more
wiley   +1 more source

Post-Golgi supramolecular assembly of aquaporin-4 in orthogonal arrays. [PDF]

open access: yesTraffic, 2012
Rossi A   +3 more
europepmc   +1 more source

Kinesin‐Induced Buckling Reveals the Limits of Microtubule Self‐Repair

open access: yesAdvanced Science, EarlyView.
This study shows that kinesin‐driven buckling induces extensive microtubule lattice damage that often exceeds intrinsic self‐repair and leads to filament failure. While curvature, motor motility, and force individually cause limited damage, their combination overwhelms repair.
Shweta Nandakumar   +9 more
wiley   +1 more source

Nonrelativistic Spin Current Generated Unconventional Spin Hall Magnetoresistance in Altermagnetic RuO2

open access: yesAdvanced Science, EarlyView.
It is reported that the unconventional spin Hall magnetoresistance generated from nonrelativistic spin currents in RuO2 is capable of accurately detecting spin current polarization and disentangling the T̂$\hat{T}$‐odd and T̂$\hat{T}$‐even components of a spin current.
Chang Pan   +10 more
wiley   +1 more source

Full-parameter-modulated three-dimensional vectorial generalized vortex array. [PDF]

open access: yesLight Sci Appl
Zhang X   +11 more
europepmc   +1 more source

Beyond Extracellular Vesicle (EV) Hype: Practical Solutions and Remaining Hurdles in EV Research, Manufacturing, and Clinical Translation

open access: yesAdvanced Science, EarlyView.
ABSTRACT Extracellular vesicles (EVs) are nanoscale mediators of intercellular communication with diverse molecular cargoes that reflect their cell of origin. Advances in isolation, detection, and single‐particle analytics have revealed increasing molecular and functional heterogeneity, while exposing limitations in how EV identity and activity are ...
David J. Lundy   +8 more
wiley   +1 more source

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