Results 191 to 200 of about 118,006 (248)

A Novel Compact Multi-Reflecting Time-of-Flight Mass Spectrometer. [PDF]

J Am Soc Mass Spectrom
Verenchikov AN, Wildgoose J, Kirillov SN, Vorobyev AV, Makarov VV, Gethings LA, Tonge RP, Daly ME, Johnson WJ, Langridge JI.   +9 more
europepmc   +1 more source

ACSL1‐Dependent Microglial Lipoimmunometabolic Reprogramming Underlies Cognitive Deficits in Alcohol Use Disorder

Advanced Science, EarlyView.
This study reveals that chronic alcohol exposure selectively upregulates ACSL1 expression in prefrontal cortical microglia, driving lipid metabolism reprogramming and lipid droplet accumulation, which activates the NLRP3 inflammasome and sustains neuroinflammation. To reverse this process, a dual‐targeted lipid nanoparticle, siACSL1@LNP‐MR, is designed
Liang Hao, Xing‐Rui Cao, Bai‐Qiang Li, Fu‐Ying Zhao, Jia‐Mei Wang, Rui‐Kang Gao, Zhi‐Peng Cao, Zhen‐Xian Du, Hua‐Qin Wang   +8 more
wiley   +1 more source

A low-complexity compact dual-polarized patch antenna with high isolation and low cross-polarization for in-band full-duplex applications. [PDF]

Sci Rep
Tran-Huy H, Hoang-Thu T, Le-Tuan T, Alibakhshikenari M, Qasaymeh YM, Saber T, Livreri P.   +6 more
europepmc   +1 more source

A NeuroD1 AAV‐Based Gene Therapy for Functional Brain Repair in Alzheimer's Disease‐Like Non‐Human Primate Model

Advanced Science, EarlyView.
This study tests NeuroD1 AAV‐based gene therapy in a non‐human primate Alzheimer's disease model. The therapy prevents neuronal damage, inhibits hippocampal atrophy, and reduces neuroinflammation. It also repairs vascular and blood‐brain barrier damage, restores cerebrospinal fluid biomarkers, enhances hippocampal glucose metabolism, and improves ...
Zhouquan Jiang, Yongpeng Qin, Bin Luo, Fan Bai, Jiangyue Liu, Long Ma, Shu He, Rongjie Chen, Yuchen Wang, Shanggong Liu, Ying Sun, Yi Chen, Shuo Zhang, Jiaqi Liang, Feng Liao, Huiyi Wei, Junjie Wei, Lu Wang, Hao Xu, Zheng Wu, Gong Chen, Wenliang Lei   +21 more
wiley   +1 more source

High-capacity and secure inter-satellite optical wireless communication using 2D DPS-OCDMA. [PDF]

Sci Rep
Armghan A, Abd El-Mottaleb SA, Aldkeelalah SS, Chaoui S, Emara A, Singh M.   +5 more
europepmc   +1 more source

Spin Hall Nano‐Antenna

Advanced Science, EarlyView.
ABSTRACT The spin Hall effect is a well‐known phenomenon in spintronics that has found numerous applications in digital electronics (memory and logic), but relatively few in analog electronics. Practically the only analog application in widespread use is the spin Hall nano‐oscillator (SHNO) that delivers a high frequency alternating current or voltage ...
Raisa Fabiha, Pratap Kumar Pal, Michael Suche, Amrit Kumar Mondal, Erdem Topsakal, Anjan Barman, Supriyo Bandyopadhyay   +6 more
wiley   +1 more source

Dual-state six-channel polarization multiplexing in reconfigurable metasurfaces. [PDF]

Nanophotonics
Xie S, Jia T, Ma X, Li B, Zhang R, Li Z, Yun B, Heo H, Jeon N, Rui G, Rho J.   +10 more
europepmc   +1 more source

CD28‐Targeted Enzyme‐Responsive Conformation‐Switching Peptide Self‐Assembly for Selective T‐Cell Acute Lymphoblastic Leukemia (T‐ALL) Therapy

Advanced Science, EarlyView.
We developed the enzyme‐responsive peptide SAp‐CD28 to selectively target CD28‐overexpressing T‐ALL cells. Following phosphatase‐mediated activation, SAp‐CD28 undergoes conformational switching and nanooligomerization, resulting in the disruption of CD28 downstream signaling.
Jun Li, Ziyu Jia, Dekun Li, Zhi‐Wen Hu, Yinghao Ding, Shengyi Zhang, Shengkun Tuo, Zhimou Yang, Huisheng Fu, Ling Wang, Man‐Di Wang   +10 more
wiley   +1 more source

Energy-Controllable Manipulation on Surface Waves and Propagating Waves by Bifunctional Metasurfaces. [PDF]

Nanophotonics
Li S, Kang M, Pan W, Wang Y, Chen Y, Peng X, Jin X, Li J, Dong S, Zhou L, Sun S.   +10 more
europepmc   +1 more source