Results 211 to 220 of about 345,056 (285)

Stimuli‐Responsive Supramolecular Biomaterials for Cancer Theranostics

Advanced Science, EarlyView.
The ultimate goal of cancer theranostics is to get imaging agents and therapeutic cargo to tumor sites when and where they are required. “Smart” systems should be developed. This review discusses the characteristics of physiological stimuli, types and action modes of external stimuli, construction approaches and working principles, as well as ...
Wenting Hu, Binglin Ye, Guocan Yu, Feihe Huang, Zhengwei Mao   +4 more
wiley   +1 more source

Study and Optimal Design of the Integrated 37° Unidirectional SV-EMAT for Rapid Rail Flaw Detection. [PDF]

Sensors (Basel)
Yuan W.
europepmc   +1 more source

S3RL: Enhancing Spatial Single‐Cell Transcriptomics With Separable Representation Learning

Advanced Science, EarlyView.
Separable Spatial Representation Learning (S3RL) is introduced to enhance the reconstruction of spatial transcriptomic landscapes by disentangling spatial structure and gene expression semantics. By integrating multimodal inputs with graph‐based representation learning and hyperspherical prototype modeling, S3RL enables high‐fidelity spatial domain ...
Laiyi Fu, Penglei Wang, Gaoyuan Xu, Jitao Lu, Qinke Peng, Danyang Wu, Hequan Sun   +6 more
wiley   +1 more source

Enhancing Human-Robot Compatibility in Shoulder Exoskeletons: Passive Joint Optimization of PP<u>RRR</u>P vs. <u>RRR</u>UP Configurations. [PDF]

Biomimetics (Basel)
Cao Q, Shan W, Liu Y, Yuan Y.
europepmc   +1 more source

Engineering Compact Base Editors by AlphaFold‐Guided Mutation Scan and Escherichia coli‐Based Tri‐Selection

Advanced Science, EarlyView.
A miniaturized deaminase SsdAtox was scanned with AlphaFold to identify DNA binding pocket hot spots. Site‐saturation mutagenesis at gatekeeper residue K31 yielded ten‐fold activity enhancement. Trinity Screen, an E. coli‐based three‐in‐one platform selecting for high activity and reduced double‐strand breaks, enabled combinatorial evolution at DNA ...
Ryeo Gang Son, Goeun Kim, Jungjoon K. Lee   +2 more
wiley   +1 more source

ClinMAVE: a curated database for clinical application of data from multiplexed assays of variant effect. [PDF]

Nucleic Acids Res
Ma C, Li Z, Tang X, Li P, Li L, Wang S, Wu J, Luo L, Liu Y, Zhang Z, Wang X.   +10 more
europepmc   +1 more source

Modelling of river morphology with non-orthogonal horizontal curvilinear coordinates

, 1991
E. Mosselman
openalex   +1 more source

Pirin Transcriptionally Regulates PLA2G4A To Inhibit Ferroptosis in Colorectal Cancer via Lipid Profile Remodeling

Advanced Science, EarlyView.
This study identifies Pirin (PIR), an iron‐binding protein, as a critical ferroptosis suppressor in colorectal cancer through lipid membrane remodeling. PIR, induced by NRF2 during ferroptotic stress, transcriptionally regulates PLA2G4A to shift cellular lipid composition away from ferroptosis‐permissive polyunsaturated phospholipids.
Wei Shi, Yue Qi Ong, Prativa Majee, Esther SM Wong, Amhed Missael Vargas Velazquez, Kerem Fidan, Pierce Kah‐Hoe Chow, Wai Leong Tam, Ker Kan Tan, Iain Beehuat Tan, Vinay Tergaonkar   +10 more
wiley   +1 more source

Jacobi-Ritz formulation for modal analysis of thick, anisotropic and non-uniform electric motor stator assemblies considering axisymmetric vibration modes. [PDF]

Meccanica
Andreou P, Hajjaj AZ, Mohammadpour M, Theodossiades S.   +3 more
europepmc   +1 more source

Accelerating Variable Cell Shape Molecular Dynamics with a Position-Dependent Mass Matrix. [PDF]

J Chem Theory Comput
Sommer-Jörgensen M, Krummenacher M, Goedecker S.   +2 more
europepmc   +1 more source