Antibody drug conjugates deliver their cytotoxic anti‐tubulin or topoisomerase I inhibitor payloads to tumors through cancer cell receptor targeting. The released drug payloads induce cellular changes that interact with radiotherapy resulting in radiosensitization that improves cancer cell kill and stimulates anti‐tumor immune responses.
Jacqueline Lesperance +17 more
wiley +1 more source
A Sparse Bayesian Technique to Learn the Frequency-Domain Active Regressors in OFDM Wireless Systems. [PDF]
Crespo-Cadenas C +4 more
europepmc +1 more source
A Sharp Condition for Exact Support Recovery With Orthogonal Matching Pursuit
Jinming Wen +4 more
semanticscholar +1 more source
Using machine learning on a mega‐scale global dataset (n = 1,336,840) reveals a robust personality trait architecture beyond the Big Five. A Big Two model, broadly capturing social engagement and internal mentation, defines a geometric space that links personality to neurocognitive profiles.
Kaixiang Zhuang +7 more
wiley +1 more source
A Novel Matching Pursuit Modeling Strategy Based on Adaptive Fourier Decomposition Theory for Predicting Antigenic Variation of Influenza A (H1N1). [PDF]
Qu W +8 more
europepmc +1 more source
Early Radiation Therapy Response Assessment Using Multi‐Scale Photoacoustic Imaging
Tomographic and mesoscopic photoacoustics capture intratumoural features of radioresistance and response. ABSTRACT There is a critical unmet clinical need to identify biomarkers that predict and detect radiation therapy (RT) response in cancer. Using the unique capabilities of multi‐scale photoacoustic imaging (PAI) to depict tumor oxygenation and ...
Thierry L. Lefebvre +12 more
wiley +1 more source
Spurious Spike Elimination using Sparse Signal Processing Improves Seizure Onset Zone Delineation in Brief Intraoperative iEEG Recordings. [PDF]
Ayyoubi AH +6 more
europepmc +1 more source
Stochastic nanoscale physical cues induce glioblastoma (GBM)‐associated transcriptional traits in naïve astrocytes leading to spontaneous formation of spheroids. Cells within spheroids express activated‐MMP2 and a differential gene expression pattern involving P53 and NOTCH3, providing evidence for a role for changes in brain topography, as observed in
Laurent Starck +8 more
wiley +1 more source
Ultrasonic Time-of-Flight Diffraction Imaging Enhancement for Pipeline Girth Weld Testing via Time-Domain Sparse Deconvolution and Frequency-Domain Synthetic Aperture Focusing. [PDF]
Wu E, Han Y, Yu B, Zhou W, Tian S.
europepmc +1 more source

