Results 221 to 230 of about 410,574 (281)

A Mathematical Analysis of IPT-DMFT. [PDF]

Commun Math Phys
Cancès E, Kirsch A, Perrin-Roussel S.
europepmc   +1 more source

Engineered Transformer Base Editor with Enhanced Editing Efficiency

Advanced Science, EarlyView.
A highly efficient transformer base editor system achieves robust genomic editing in a humanized mouse model. This work establishes a versatile and translatable platform, opening new avenues for precision gene therapy. ABSTRACT Canonical cytosine base editors (CBEs) achieve precise C‐to‐T conversions without inducing DNA double‐strand breaks (DSBs ...
Bowen Chen, Letong Liang, Rui Xu, Tianyi Wang, Hongyan Chen, Daru Lu   +5 more
wiley   +1 more source

Phase locking and multistability in the topological Kuramoto model on cell complexes. [PDF]

Nat Commun
Bačić I, Schaub MT, Kurths J, Witthaut D.   +3 more
europepmc   +1 more source

Seeing the Chemistry of Biomolecular Condensates: In Situ Mapping of Composition and Water Content

Advanced Science, EarlyView.
Raman hyperspectral imaging combined with spectral phasor analysis enables a label‐free quantification of proteins, polymers and water density within individual biomolecular condensates. By transforming complex vibrational fingerprints into intuitive compositional maps, the approach reveals the high water content and structural heterogeneity of ...
E. Sabri, A. Mangiarotti, C. N. Z. Schmitt, R. Dimova   +3 more
wiley   +1 more source

Method for Determining Contact Temperature of Tool Rake Face During Orthogonal Turning of Ti-6Al-4V Alloy. [PDF]

Materials (Basel)
Ślusarczyk Ł, Twardowska A.
europepmc   +1 more source

Targeted Lysosomal Degradation of Extracellular and Membrane Proteins: From Receptor Hijacking to Programmable Endolysosomal Routing

Advanced Science, EarlyView.
Targeted chimeric degraders engage extracellular or membrane proteins and endocytosable cell‐surface receptors, forming ternary complexes that induce receptor‐mediated internalization. Following endocytosis, post‐endocytic sorting—not internalization alone—determines target fate.
Ke Liu, Xiyan Wang, Xiaozhen Liu, Chaoqi He, Da Qian, Xuli Meng, Liquan Zhu   +6 more
wiley   +1 more source

Delay-Energy-Aware Partial Offloading and Coupled Resource Allocation in Hybrid NOMA-MEC Networks: Derivations and Reproducible Evaluation. [PDF]

Sensors (Basel)
Bataineh JKJ, Jawarneh AS, Hayajneh KF, Albataineh Z.   +3 more
europepmc   +1 more source

Lipid-Shell PARCH: A Physically Motivated Scale for Transmembrane Residue Hydropathy. [PDF]

J Phys Chem B
Mandal R, Nangia S.
europepmc   +1 more source

Common bean exhibits low zinc translocation efficiency to grain under zinc enriched field conditions in Malawi. [PDF]

Discov Plants
Matumba AM, Chimungu JG, Lark RM, Monjerezi M, Wilson L, Limuwa MM, Broadley MR, Ander EL, Bailey EH, Nalivata PC.   +9 more
europepmc   +1 more source