Results 221 to 230 of about 357,436 (278)

DSG2+ Cancer Stem Cells Co‐Located With FAP+ Myofibroblasts in the Tumor Boundary That Determines the Efficacy of Immunotherapy in Non‐Small Cell Lung Cancer

Advanced Science, EarlyView.
Cancer stem cells (CSCs) in non‐small cell lung cancer display pronounced plasticity and spatial heterogeneity. By integrating single‐cell and spatial transcriptomics, this study defines a DSG2‐associated CSC program and reveals a tumor‐margin niche formed with FAP+ myofibroblasts.
Guangyu Fan, Le Tang, Tongji Xie, Mengwei Yang, Lin Li, Sheng Yang, Puyuan Xing, Xiaohong Han, Yuankai Shi   +8 more
wiley   +1 more source

Unbroken P T -symmetry in the absence of gain or loss. [PDF]

Nat Commun
Bentzien J, Pinske J, Maczewsky LJ, Weimann S, Heinrich M, Scheel S, Szameit A.   +6 more
europepmc   +1 more source

Modulating Integrin and Growth Factor Signaling With Peptides: Strategies to Synergistically Enhance Bone Tissue Regeneration

Advanced Science, EarlyView.
It has been demonstrated that, in the bone extracellular matrix (ECM), integrins and growth factor receptors (GFRs) engage in synergistic signaling to guide bone healing and regeneration. This review provides a comprehensive overview of current strategies using ECM‐derived peptides to recreate the cellular microenvironment and harness synergistic ...
Lluís Oliver‐Cervelló, Elisabetta Ada Cavalcanti‐Adam, Carlos Mas‐Moruno   +2 more
wiley   +1 more source

The identification of biomarkers for response to omalizumab in adult asthma based on untargeted metabolomic analysis. [PDF]

Medicine (Baltimore)
Li Y, Zhang Y, Zhao L, Li W, Jia W, Ma H.   +5 more
europepmc   +1 more source

NIBV Induces Incomplete Autophagy via AMPK‐TFEB, Causing Kidney Injury in Chicks

Advanced Science, EarlyView.
This study reveals that NIBV can inhibit the nuclear translocation of TFEB by suppressing the expression of AMPK, leading to the blockade of autophagolysosomal functions, in turn increasing NIBV replication and triggering severe kidney injury in chicks.
Cheng Huang, Yizhou Zeng, Yunfeng Chen, Zhengqing Li, Salma Mbarouk Omar, Shengwei Zhong, Ping Liu, Zhanhong Zheng, Gaofeng Cai, Xiaona Gao, Xiaoquan Guo   +10 more
wiley   +1 more source

Investigating urea is an ideal additive to the Accu-OptiClearing delipidation cocktail. [PDF]

Sci Rep
Lai MS, Chick WM, Law RMH, Chang RC.
europepmc   +1 more source

Vectorcardiography at rest and during exercise in horses using the Delta (Δ) 12-lead configuration. [PDF]

J Vet Intern Med
Paulussen E, Delhaas T, Decloedt A, van Loon G, Van Steenkiste G.   +4 more
europepmc   +1 more source

Enhanced RGB-D SLAM through orthogonal plane constraints and point-line-plane collaborative optimization. [PDF]

PLoS One
Yang G, Liu P, Ma W.
europepmc   +1 more source

Cones of Noether-Lefschetz divisors and moduli spaces of hyperkähler manifolds. [PDF]

Math Ann
Barros I, Beri P, Flapan L, Williams B.
europepmc   +1 more source