Results 241 to 250 of about 491,261 (311)

Polarization-Reconfigurable Metasurface Antenna Design for Drone Terminals Based on Characteristic Mode Analysis. [PDF]

Micromachines (Basel)
Zhang S, Yu H, Wen X, Zheng H.
europepmc   +1 more source

Timing Mechanotransduction: Mechanically Dynamic Biomaterials Reveal the Temporal Hierarchy of YAP/TAZ Control Nodes

Advanced Science, EarlyView.
This work develops dynamically softening polyacrylamide hydrogels for time‐resolved imaging during continuous mechanical transitions. The study revealed that mechanotransduction is biphasic; YAP/TAZ inactivation is driven by early loss of the nucleocytoskeletal continuum connecting subnuclear adhesions, F‐actin, and the nuclear envelope, coupled with ...
Alessandro Gandin, Giada Vanni, Veronica Torresan, Margherita Pelosin, Rebecca Busetto, Anna Citron, Ambela Suli, Paolo Contessotto, Carlo Albanese, Francesca Zanconato, Tito Panciera, Stefano Piccolo, Giovanna Brusatin   +12 more
wiley   +1 more source

De Novo Design and Directed Evolution Refinement of Mirror‐Image Protein Binders Targeting Interleukin‐4

Advanced Science, EarlyView.
This study presents the de novo design and directed evolution of a mirror‐image D‐protein inhibitor targeting human interleukin‐4 (IL‐4). The engineered molecule exhibits nanomolar binding affinity for IL‐4 and effectively inhibits IL‐4–mediated signaling.
Liqing Xu, Yuxiang Ren, Tongyue Wang, Hongyong Li, Yue Yao, Lei Liu, Ke Sun, Peilong Lu   +7 more
wiley   +1 more source

Understanding and Overcoming Antibody‐Drug Conjugate Resistance: Biological Mechanisms and Emerging Analytical Frameworks in Breast Cancer

Advanced Science, EarlyView.
Antibody–drug conjugates (ADCs) transform breast cancer therapy, yet resistance limits their durability. Emerging evidence reveals that ADC failure is not solely tumor‐intrinsic but shaped by dynamic tumor–microenvironment interactions that alter drug delivery, processing, and response.
Minji Seo, Jangsoon Lee, Naoto T. Ueno
wiley   +1 more source

Dynamic Beam Control-Based Neighbor Discovery Protocol for Underwater Acoustic Networks with Multi-Parallel Transceiver. [PDF]

Sensors (Basel)
Zhang J, Zhou L, Wang H, Zeng Z, Hu Q.
europepmc   +1 more source

Size‐Modulated Mesoderm‐Endoderm Divergence and Myocardial Cavitation in Micropatterned Cardioids

Advanced Science, EarlyView.
Micropatterned cardioids, CRISPR‐engineered reporter hiPSCs, deep‐tissue imaging, and single‐cell RNA sequencing are integrated to model mesoderm‐endoderm co‐development. Heart‐foregut crosstalk promotes single large cavitation inside cardioids, resembling early heart chamber formation. ABSTRACT The human heart, originating from the splanchnic mesoderm,
Plansky Hoang, David W. McKellar, Andrew Kowalczewski, Nhu Y. Mai, Meng Chai, Xiaojun L. Lian, Yi Zheng, Jeffrey Amack, Nathan Tucker, Iwijn De Vlaminck, Huaxiao Yang, Benjamin D. Cosgrove, Zhen Ma   +12 more
wiley   +1 more source

Guest Editorial: Introduction to the Special Section on Orthogonal Time Frequency Space Modulation and Delay-Doppler Signal Processing

IEEE Open Journal of Vehicular Technology
Qin Tao, Shuangyang Li, Weijie Yuan, Slawomir Stanczak, Emanuele Viterbo, Xianbin Wang   +5 more
doaj   +1 more source

Quantized soliton pumping governed by high-dimensional Chern invariants. [PDF]

Natl Sci Rev
Di F, Zhang W, Yuan H, Qian L, Cao W, Zhou X, Zhang X.   +6 more
europepmc   +1 more source

Arbitrary Total Angular Momentum Vectorial Holography Using Bi-Layer Metasurfaces. [PDF]

Adv Mater
Jung J, Kim H, Shin J.
europepmc   +1 more source

Experimental study of fluid-thermal-structural interactions in a Mach-10 compression corner using super-ellipse-based photogrammetry. [PDF]

Exp Fluids
Duchene TA, Schöneich AG, Bathel BF, Weisberger JM, Buck GM, Bodony DJ, Laurence SJ.   +6 more
europepmc   +1 more source