Results 1 to 10 of about 18,250 (170)

Chicken Pulmonary MicroRNAs Targeting the PB2 (Segment 1) of Avian Influenza Virus

Animal Research and One Health, EarlyView.
The PB2 segment of H5N1 is essential for replication and host adaptation. We screened 200 miRNAs and identified five (gga‐miR‐17‐3p, gga‐miR‐29a‐5p, gga‐miR‐1718, gga‐miR‐16c‐5p, and gga‐miR‐1744‐5p) using thermodynamic stability of heteroduplex, seed sequence complementarity, conservation, and accessibility, offering insights into host antiviral ...
Akanksha Choudhary, Nidhishree N. S, Rakesh Kumar Pundir, Muhasin Asaf V. N, Anamika Mishra, Ashwin Ashok Raut, Megha Agarwal, Amod Kumar   +7 more
wiley   +1 more source

The Role of miRNAs in Chicken Immune Regulation and Prospects for Disease‐Resistant Breeding

Animal Research and One Health, EarlyView.
A schematic workflow illustrating the screening of disease‐resistant miRNAs and the generation of miRNA‐based disease‐resistant chickens via PGC‐mediated germline genome editing. ABSTRACT MicroRNAs (miRNAs) are emerging as pivotal regulators of the immune system, playing a decisive role in shaping disease resistance in chicken.
Qiangzhou Wang, Weiran Wu, Qingqing Cai, Jiaxing Wang, Qi Gao, Muhammad Iftikhar, Yulin Bi, Hao Bai, Lihong Gu, Guobin Chang, Shihao Chen   +10 more
wiley   +1 more source

Prevalence of Eight Viruses in Captive Amur Tigers (Panthera tigris altaica) From Harbin, China 中国哈尔滨市圈养东北虎8种病毒的流行

Wildlife Letters, EarlyView.
The Amur tiger, an endangered flagship species mainly found in the Russia Far East and Northeastern China, holds immense biological importance, and has been listed under the Convention on International Trade in Endangered Species of Wild Fauna and Flora (CITES).
Wei Xie, Luyao Wang, Mengna Chen, Qinjie Chang, Hongyu Jiang, Haitao Xu, Liu Dan, Xiang Li, Yulong Wang, Xiangwei Zeng, Bin Yang, Miaowei Wang, Yonggang Jiang, Hongliang Chai, Siyuan Yang, Yajun Wang   +15 more
wiley   +1 more source

Ocular Manifestations of Infectious Salmon Anaemia Virus Infection in Atlantic Salmon (Salmo salar)

Journal of Fish Diseases, Volume 49, Issue 11, November 2026.
ABSTRACT Eyes are essential sensory organs needed by teleost Atlantic salmon for high visual acuity and survival in both the wild and in aquaculture settings. In this work, we assessed the ocular manifestations of Infectious Salmon Anaemia Virus (ISAV) infection in Atlantic salmon by a cohabitation‐mediated infection assay and histological and ...
Emily Mahon, Rebecca R. Kwabiah, Hélène Paradis, Manuel A. Soto‐Dávila, Sathees Duglas, Raja Ram Gurung, Thurka Paramanathan, Ignacio Vasquez, Shams Al‐Badoosh, John Law, Javier Santander, Mark D. Fast, Robert L. Gendron   +12 more
wiley   +1 more source

Dual Antiviral and Immunomodulatory Effects of Phytochemicals in Influenza A Virus Infection: Targeting Key Host Signaling Pathways

MicrobiologyOpen, Volume 15, Issue 5, October 2026.
Influenza A virus modulates host innate immune pathways, including TLR, RIG‐I, MAPK, and NF‐κB signaling, to support replication and drive inflammatory pathology. Plant‐derived phytocompounds target these interconnected pathways, offering a potential host‐directed immunomodulatory approach complementary to conventional antivirals.
Dibakar Chowdhury, Hillary A. Vanderven, Phurpa Wangchuk, Subir Sarker   +3 more
wiley   +1 more source

RNA viral protein structure database: A comprehensive and user‐friendly web database for RNA viral protein structures

iMetaOmics, Volume 3, Issue 3, September 2026.
Given the central role of protein structures in RNA virus biology, the RNA viral protein structure database (RVPSD, https://virus.9itsg.net) integrates taxonomic classification, viral nucleotide and protein sequences, functional annotations, and predicted three‐dimensional protein structures.
Qiangzhen Yang, Zhongshuai Tian, Tao Hu, Jiangrong Lou, Hengcong Liu, Edward C. Holmes, Yongyong Shi, Juan Li, Weifeng Shi   +8 more
wiley   +1 more source

Airborne Virus Shedding of Respiratory Syncytial Virus Compared to Influenza A Virus in Hospitalized Patients

Journal of Medical Virology, Volume 98, Issue 9, September 2026.
ABSTRACT Airborne transmission is an important route for the spread of respiratory viruses. To assess the potential for airborne shedding of influenza A virus (IAV) and respiratory syncytial virus (RSV), this study compared the presence of viral RNA in air samples collected near hospitalized patients.
Stijn de Man, Evert‐Jan Wils, Armand Paauw, Yesim Delice‐Ikiz, Wessel Hanselaar, Han J. C. Veltman, Gerda Doejaaren, Chelton van Laaren, Kim van den Bosch, Vincent Vermeule, Peter de Man, David S. Y. Ong   +11 more
wiley   +1 more source

Emergence of Novel Highly Pathogenic Avian Influenza Virus A(H5N1) Clade 2.3.4.4b in Commercial Poultry, Bangladesh

Influenza and Other Respiratory Viruses, Volume 20, Issue 9, September 2026.
ABSTRACT Background The high‐pathogenicity avian influenza (HPAI) viruses represent a main threat to animal and human health, poultry productivity, and ecosystems. The newly evolved A(H5N1) clade 2.3.4.4b has become a worldwide concern for its expanding multihost ecology, including poultry and a wide range of mammalian species.
Mohammed A. Samad, Md Rezaul Karim, Amelia Coggon, Anowar Hossen, A. S. M. Ashab Uddin, Md Golbar Hossain, Guillaume Fournie, Nicola S. Lewis, Alexander M. P. Byrne   +8 more
wiley   +1 more source

Prognostic Value of Clinical and Laboratory Markers in Hospitalized Influenza‐Positive Patients: A Retrospective Cohort Study With ROC‐Based Risk Stratification

Health Science Reports, Volume 9, Issue 8, August 2026.
ABSTRACT Background and Aims Seasonal influenza continues to cause substantial morbidity and mortality worldwide. Identifying reliable clinical and paraclinical predictors of adverse outcomes may aid in early triage and management. This study aimed to evaluate clinical and paraclinical factors associated with prolonged hospitalization, ICU admission ...
Mohsen Daneshmand, Arefeh Ebrahimian Shiadeh, Farzane Sadeghi, Hemmat Gholinia, Farzin Sadeghi, Masomeh Bayani   +5 more
wiley   +1 more source

SNHG15 Positively Regulates Influenza Virus Infection Through Its Association With miR‐153 and RABL2A

Journal of Medical Virology, Volume 98, Issue 8, August 2026.
ABSTRACT Influenza viruses cause seasonal epidemics, and current vaccines do not fully protect against them. This study focuses on long non‐coding RNAs (lncRNAs), which are RNA molecules that do not code for proteins but play crucial roles in various biological processes. We identified 17 lncRNAs altered by the influenza virus.
Samuel Pushparaj, Kishore Vaddadi, Chaoqun Huang, Yurong Liang, Dao Xu, Gayan Bamunuarachchi, Prince Jhandai, Keerthana Santhosh, Elizabeth Varghese, Lin Liu   +9 more
wiley   +1 more source