Human and Murine IFIT1 Proteins Do Not Restrict Infection of Negative-Sense RNA Viruses of the Orthomyxoviridae, Bunyaviridae, and Filoviridae Families [PDF]
UNLABELLED: Interferon-induced protein with tetratricopeptide repeats 1 (IFIT1) is a host protein with reported cell-intrinsic antiviral activity against several RNA viruses.
Amelia K Pinto+2 more
exaly +11 more sources
Introduction. Variants of influenza virus A/H7 have the same high pandemic potential as A/H5. However, the information about the antigenic structure of H7 hemagglutinin (НА) is considerably inferior in quantitative terms to similar data for H5 НА.
E. V. Sorokin+8 more
doaj +6 more sources
The family Orthomyxoviridae contains significant pathogens of humans and animals. Virions are spherical to filamentous, about 100 nm in diameter. Genomes are segmented, single-stranded negative-strand RNA. Influenza A virus infects a wide variety of mammals and birds, replicating in the respiratory and/or gastrointestinal tracts.
Susan Payne
exaly +5 more sources
Upolu virus and Aransas Bay virus, Two Presumptive Bunyaviruses, Are Novel Members of the Family Orthomyxoviridae [PDF]
ABSTRACT Emerging and zoonotic pathogens pose continuing threats to human health and ongoing challenges to diagnostics. As nucleic acid tests are playing increasingly prominent roles in diagnostics, the genetic characterization of molecularly uncharacterized agents is expected to significantly enhance detection and surveillance ...
W Ian Lipkin, Weisheng Liu
exaly +5 more sources
Immunoprofiles of COVID-19 uniquely differentiated from other viruses: A machine learning investigation of multiplex immunoassay data. [PDF]
Cytokines and chemokines are vital in maintaining a healthy state by efficiently controlling invading microbes. In addition, the dysregulation of these immune mediators can contribute to viral infection pathology. We comprehensively analyzed the profiles
Kaur A, Krishnan VV.
europepmc +3 more sources
Characterization of Three Novel Viruses from the Families Nyamiviridae, Orthomyxoviridae, and Peribunyaviridae, Isolated from Dead Birds Collected during West Nile Virus Surveillance in Harris County, Texas [PDF]
This report describes and characterizes three novel RNA viruses isolated from dead birds collected during West Nile virus surveillance in Harris County, TX, USA (the Houston metropolitan area).
Peter J. Walker+15 more
doaj +2 more sources
Experimental Infection of Amblyomma americanum (Acari: Ixodidae) With Bourbon Virus (Orthomyxoviridae: Thogotovirus) [PDF]
Abstract Following the recent discovery of Bourbon virus (BRBV) as a human pathogen, and the isolation of the virus from Amblyomma americanum (L.) collected near the location of a fatal human case, we undertook a series of experiments to assess the laboratory vector competence of this tick species for BRBV.
Nicole E. Breuner+6 more
openaire +4 more sources
Introduction. Influenza is one of the most pressing global health problems. Despite the wide range of available anti-influenza drugs, the viral drug resistance is an increasing concern and requires the search for new approaches to overcome it.
Evgeny A. Pashkov+12 more
doaj +3 more sources
INFLUENZA D VIRUSES - PATHOGENS FORMING A NEW GENUS IN THE ORTHOMYXOVIRIDAE FAMILY
Influenza pathogens belong to the Orthomyxoviridae family and are divided into genera: Influenzavirus A, B, C, D, as well as Quaranjavirus, Thogotovirus, and Isavirus. For the first time, the influenza D virus was isolated from swine nasal swabs in 2011 in the United States, and its widespread distribution among cattle in France, China, Italy ...
M. Kh. Sayatov+3 more
+4 more sources
The coding region of segment 4 of Thogoto (THO) virus, a tick-borne member of the Orthomyxoviridae, was expressed in a baculovirus system under the control of the polyhedrin promoter. This construct expressed authentic envelope glycoprotein as determined by size and antigenic reactivity with a panel of monoclonal antibodies (MAbs).
Linda D. Jones+3 more
openaire +4 more sources