Introduction. Variants of influenza virus A/H7 have the same high pandemic potential as A/H5. However, the information about the antigenic structure of H7 hemagglutinin (НА) is considerably inferior in quantitative terms to similar data for H5 НА.
E. V. Sorokin+8 more
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The family Orthomyxoviridae contains significant pathogens of humans and animals. Virions are spherical to filamentous, about 100 nm in diameter. Genomes are segmented, single-stranded negative-strand RNA. Influenza A virus infects a wide variety of mammals and birds, replicating in the respiratory and/or gastrointestinal tracts.
Susan Payne
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Human and Murine IFIT1 Proteins Do Not Restrict Infection of Negative-Sense RNA Viruses of the Orthomyxoviridae, Bunyaviridae, and Filoviridae Families [PDF]
ABSTRACT Interferon-induced protein with tetratricopeptide repeats 1 (IFIT1) is a host protein with reported cell-intrinsic antiviral activity against several RNA viruses. The proposed basis for the activity against negative-sense RNA viruses is the binding to exposed 5′-triphosphates (5′-ppp) on the genome of viral RNA. However,
Amelia K Pinto+2 more
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Upolu virus and Aransas Bay virus, Two Presumptive Bunyaviruses, Are Novel Members of the Family Orthomyxoviridae [PDF]
ABSTRACT Emerging and zoonotic pathogens pose continuing threats to human health and ongoing challenges to diagnostics. As nucleic acid tests are playing increasingly prominent roles in diagnostics, the genetic characterization of molecularly uncharacterized agents is expected to significantly enhance detection and surveillance ...
W Ian Lipkin, Weisheng Liu
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Characterization of Three Novel Viruses from the Families Nyamiviridae, Orthomyxoviridae, and Peribunyaviridae, Isolated from Dead Birds Collected during West Nile Virus Surveillance in Harris County, Texas [PDF]
This report describes and characterizes three novel RNA viruses isolated from dead birds collected during West Nile virus surveillance in Harris County, TX, USA (the Houston metropolitan area).
Peter J. Walker+15 more
doaj +2 more sources
Introduction. Influenza is one of the most pressing global health problems. Despite the wide range of available anti-influenza drugs, the viral drug resistance is an increasing concern and requires the search for new approaches to overcome it.
Evgeny A. Pashkov+12 more
doaj +3 more sources
Experimental Infection of Amblyomma americanum (Acari: Ixodidae) With Bourbon Virus (Orthomyxoviridae: Thogotovirus) [PDF]
Abstract Following the recent discovery of Bourbon virus (BRBV) as a human pathogen, and the isolation of the virus from Amblyomma americanum (L.) collected near the location of a fatal human case, we undertook a series of experiments to assess the laboratory vector competence of this tick species for BRBV.
Marvin S. Godsey+6 more
openalex +4 more sources
INFLUENZA D VIRUSES - PATHOGENS FORMING A NEW GENUS IN THE ORTHOMYXOVIRIDAE FAMILY
Influenza pathogens belong to the Orthomyxoviridae family and are divided into genera: Influenzavirus A, B, C, D, as well as Quaranjavirus, Thogotovirus, and Isavirus. For the first time, the influenza D virus was isolated from swine nasal swabs in 2011 in the United States, and its widespread distribution among cattle in France, China, Italy ...
Kainar Zhumatov+2 more
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Introduction. Polymerase proteins PB1 and PB2 determine the cold-adapted phenotype of the influenza virus A/Krasnodar/101/35/59 (H2N2), as was shown earlier. Objective.
Pavel A. Ivanov+10 more
doaj +3 more sources
Prevalence of respiratory viral infection in children hospitalized for acute lower respiratory tract diseases, and association of rhinovirus and influenza virus with asthma exacerbations [PDF]
PurposeIn this study, we aimed to investigate the prevalence of year-round respiratory viral infection in children with lower respiratory tract infection (LRTI) and the relationship between respiratory viral infection and allergen sensitization in ...
Jae Won Shim+2 more
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