Drug Development Research, Volume 86, Issue 2, April 2025.ABSTRACT Hemagglutinin (HA) is a viral glycoprotein that mediates influenza virus entry into the host cell and is considered a relevant viral target. We here report the identification of a class of 4‐tert‐butylphenyl‐substituted spirothiazolidinones as HA‐mediated fusion inhibitors with specific activity against influenza A/H3N2 virus.
Gözde Çınar +4 more
wiley +1 more source
Tinjauan Struktur Genetik Serta Tingkat Keganasan Virus Influenza H1n1 [PDF]
, 2010 Evaluation Structure of Genetic and Virulens Influenza Virus of H1N1. Influenza of H1N1 or Mexico Flu or Pig Influenza or of Pig Flu ( Swine Influenza or Pig Flu) representing disease of acute exhalation channel (severe) caused of virus and can be ...
Angi, A. H. (Andrijanto)
core
The K186E amino acid substitution in the canine influenza virus H3N8 NS1 protein restores its ability to inhibit host gene expression [PDF]
, 2005 Canine influenza viruses (CIVs) are the causative agents of canine influenza, a contagious respiratory disease in dogs, and include the equine-origin H3N8 and the avian-origin H3N2.
Chauché, Caroline +6 more
core +2 more sources
Influenza as a public health problem [PDF]
, 2017 Virusi su sitni, jednostavno građeni mikroorganizmi koji se nastanjuju i umnožavaju u živim stanicama ljudi i životinja. Virusi gripe ili influence pripadaju porodici Orthomyxoviridae i dijele se na influencu tipa A, B i C.
Krišković, Marina
core +1 more source
Immunopathological Approach for Avian Influenza Virus Detection in Brain of Laying Bird with Clinical Signs of Torticollis and Curled Toe Paralysis [PDF]
, 2017 Infection with avian influenza virus (AIV) in laying birds field cases often lead to clinical signs of torticollis and curled toe paralysis. Clinical signs of torticollis and curled toe paralysis is similar to the clinical signs of Newcastle disease ...
Wasito, Raden +3 more
core +3 more sources
Identification of the 3' and 5' terminal sequences of the 8 rna genome segments of european and north american genotypes of infectious salmon anemia virus (an orthomyxovirus) and evidence for quasispecies based on the non-coding sequences of transcripts [PDF]
, 2010 Background Infectious salmon anemia (ISA) virus (ISAV) is a pathogen of marine-farmed Atlantic salmon (Salmo salar); a disease first diagnosed in Norway in 1984.
Kibenge, Frederick +5 more
core +3 more sources
A comprehensive overview on the crosstalk between microRNAs and viral pathogenesis and infection
Medicinal Research Reviews, Volume 45, Issue 2, Page 349-425, March 2025.Abstract Infections caused by viruses as the smallest infectious agents, pose a major threat to global public health. Viral infections utilize different host mechanisms to facilitate their own propagation and pathogenesis. MicroRNAs (miRNAs), as small noncoding RNA molecules, play important regulatory roles in different diseases, including viral ...
Seyedeh Zahra Bahojb Mahdavi +9 more
wiley +1 more source
Liver involvement in severe human influenza A H1N1
Annals of Hepatology, 2010 Influenza A is a disease caused by a RNA virus, member of the orthomyxoviridae family. The influenza infection is characterized primarily by pulmonary affection that may advance to an acute pulmonary respiratory failure course. Hepatic involvement is not
Raúl Carrillo Esper +4 more
doaj
Nucleotide sequence and genomic organization of an ophiovirus associated with lettuce big-vein disease [PDF]
, 2002 The complete nucleotide sequence of an ophiovirus associated with lettuce big-vein disease has been elucidated. The genome consisted of four RNA molecules of approximately 7ò8, 1ò7, 1ò5 and 1ò4 kb.
Dullemans, A.M. +3 more
core +2 more sources
Activation and inhibition of sirtuins: From bench to bedside
Medicinal Research Reviews, Volume 45, Issue 2, Page 484-560, March 2025.Abstract The sirtuin family comprises seven NAD+‐dependent enzymes which catalyze protein lysine deacylation and mono ADP‐ribosylation. Sirtuins act as central regulators of genomic stability and gene expression and control key processes, including energetic metabolism, cell cycle, differentiation, apoptosis, and aging.
Francesco Fiorentino +3 more
wiley +1 more source