Human and Murine IFIT1 Proteins Do Not Restrict Infection of Negative-Sense RNA Viruses of the Orthomyxoviridae, Bunyaviridae, and Filoviridae Families [PDF]
UNLABELLED: Interferon-induced protein with tetratricopeptide repeats 1 (IFIT1) is a host protein with reported cell-intrinsic antiviral activity against several RNA viruses.
Amelia K. Pinto +12 more
openalex +6 more sources
INFLUENZA D VIRUSES - PATHOGENS FORMING A NEW GENUS IN THE ORTHOMYXOVIRIDAE FAMILY
Influenza pathogens belong to the Orthomyxoviridae family and are divided into genera: Influenzavirus A, B, C, D, as well as Quaranjavirus, Thogotovirus, and Isavirus. For the first time, the influenza D virus was isolated from swine nasal swabs in 2011 in the United States, and its widespread distribution among cattle in France, China, Italy ...
K. Kh. Zhumatov +2 more
+4 more sources
GTP-bound Human MxA Protein Interacts with the Nucleocapsids of Thogoto Virus (Orthomyxoviridae) [PDF]
Human MxA protein is an interferon-induced member of the dynamin superfamily of large GTPases. MxA inhibits the multiplication of several RNA viruses, including Thogoto virus, an influenza virus-like orthomyxovirus transmitted by ticks. Previous studies have indicated that GTP binding is required for antiviral activity, but the mechanism of action is ...
Kochs, Georg, Haller, Otto
openaire +5 more sources
Influenza B, C and D Viruses (Orthomyxoviridae)
This article summarizes current knowledge on the related influenza B and C viruses and considers the few studies on the recently identified influenza D virus. We focus on the particular viral genome organizations, the viral propagation cycles, as well as structural and functional insight into the encoded viral gene products.
Wolff, Thorsten, Veit, Michael
openaire +3 more sources
Introduction. Variants of influenza virus A/H7 have the same high pandemic potential as A/H5. However, the information about the antigenic structure of H7 hemagglutinin (НА) is considerably inferior in quantitative terms to similar data for H5 НА.The aims of the study were development and characterization of the monoclonal antibodies (MAbs) panel for ...
E. V. Sorokin +8 more
openaire +5 more sources
The 5' ends of Thogoto virus (Orthomyxoviridae) mRNAs are homogeneous in both length and sequence [PDF]
Thogoto (THO) virus is a tick-borne member of the Orthomyxoviridae whose genome consists of six segments of linear, negative sense, single-stranded RNA. To gain insight into the mechanism by which viral mRNA transcripts are initiated, poly(A)+ RNA isolated from THO virus-infected cells was characterized by (i) primer extension experiments, (ii ...
C, Albo, J, Martín, A, Portela
openaire +3 more sources
DHORI VIRUS (ORTHOMYXOVIRIDAE: THOGOTOVIRUS) INFECTION IN MICE: A MODEL OF THE PATHOGENESIS OF SEVERE ORTHOMYXOVIRUS INFECTION [PDF]
After intranasal, subcutaneous, or intraperitoneal infection with Dhori virus (DHOV), adult mice developed a fulminant and uniformly fatal illness with many of the clinical and pathologic findings seen in mice infected with H5N1 highly pathogenic avian influenza A virus.
Rosa I, Mateo +4 more
openaire +3 more sources
Quaranfil, Johnston Atoll, and Lake Chad Viruses Are Novel Members of the Family Orthomyxoviridae [PDF]
ABSTRACT Arboviral infections are an important cause of emerging infections due to the movements of humans, animals, and hematophagous arthropods. Quaranfil virus (QRFV) is an unclassified arbovirus originally isolated from children with mild febrile illness in Quaranfil, Egypt, in 1953.
Rachel M, Presti +8 more
openaire +4 more sources
Experimental Infection of Amblyomma americanum (Acari: Ixodidae) With Bourbon Virus (Orthomyxoviridae: Thogotovirus) [PDF]
Abstract Following the recent discovery of Bourbon virus (BRBV) as a human pathogen, and the isolation of the virus from Amblyomma americanum (L.) collected near the location of a fatal human case, we undertook a series of experiments to assess the laboratory vector competence of this tick species for BRBV.
Marvin S, Godsey +6 more
openaire +3 more sources
Characterization of a Novel Influenza Virus in Cattle and Swine: Proposal for a New Genus in the Orthomyxoviridae Family [PDF]
ABSTRACT We have recently reported the isolation of a novel virus, provisionally designated C/swine/Oklahoma/1334/2011 (C/OK), with 50% overall homology to human influenza C viruses (ICV), from a pig in Oklahoma. Deep RNA sequencing of C/OK virus found a matrix 1 (M1) protein expression strategy that differed from that of ICV ...
Hause, Ben M. +8 more
openaire +4 more sources

