Results 41 to 50 of about 71,899 (262)

Insights into De Quervain’s Tenosynovitis as an Unintended Consequence of Problematic Smartphone Usage: A Cross-sectional Observational Study [PDF]

Journal of Clinical and Diagnostic Research
Introduction: Smartphone use has been linked to Musculoskeletal Disorders (MSDs), particularly wrist and hand conditions like De Quervain’s Tenosynovitis (DQT), which causes inflammation of the tendons of the thumb, mainly the Abductor Pollicis Longus ...
Aswin Sugumaran, Dilip Kumar Naidu, Madhan Raju, Sabari Vaasan Lakshmikanthan, S Karthikeyan, Kevin Dhas, Vamsi Krishna, Praveen Raja   +7 more
doaj   +1 more source

Gene Therapy in Orthopaedics: Progress and Challenges in Pre-Clinical Development and Translation

Frontiers in Bioengineering and Biotechnology, 2022
In orthopaedics, gene-based treatment approaches are being investigated for an array of common -yet medically challenging- pathologic conditions of the skeletal connective tissues and structures (bone, cartilage, ligament, tendon, joints, intervertebral ...
Rachael S. Watson-Levings, Glyn D. Palmer, Padraic P. Levings, E. Anthony Dacanay, Christopher H. Evans, Steven C. Ghivizzani   +5 more
doaj   +1 more source

Ultrasound‐Activatable Piezoelectric Hydrogel Reprograms Mitochondrial Epigenetics for Osteoarthritis Therapy via the mTOR/GATD3A Axis

Advanced Science, EarlyView.
An ultrasound‐activatable piezoelectric hydrogel reprograms chondrocyte mitochondrial epigenetics via the mTOR/GATD3A axis, clearing damaged mitochondria and alleviating osteoarthritis progression in both mouse models and human cartilage explants. ABSTRACT The avascular nature of cartilage hinders drug delivery for osteoarthritis (OA) therapy.
Hui Zheng, Pengfei Yan, Peng Liu, Chang Yan, Mengqi Zhao, Zuyong Wang, Chao Ma, Rongkai Zhang, Xi Cui, Swee Hin Teoh   +9 more
wiley   +1 more source

Meniscus Root Tear: Extended Classification and Arthroscopic Repair Techniques

Arthroscopy Techniques
The meniscus root is an attachment of the anterior and posterior horns of the meniscus onto the tibia, and its primary function is to prevent extrusion under axial load. Meniscus root tear constitutes 15% to 20% of meniscus tear.
Sheetal Gupta, M.S. (Orthopaedics), Ashish BC, M.S. Orthopaedics, Sachin K. Chavan, M.S. Orthopaedics, Pakhi Gupta, M.B.B.S.   +3 more
doaj   +1 more source

Short-term outcomes of total knee arthroplasty performed with and without a tourniquet

SICOT-J, 2021
Introduction: Not using a tourniquet could improve early postoperative pain, range of motion (ROM), length of stay (LOS), and thromboembolic risk in patients undergoing total knee arthroplasty (TKA).
Grigoras Mihai, Boughton Oliver, Cleary May, McKenna Paul, Rowan Fiachra E.   +4 more
doaj   +1 more source

Regulating Cells Fate and Function to Facilitate Bone Regeneration via Designing Programmable Bio‐Interactive Materials

Advanced Science, EarlyView.
This article aims to elucidate the biological mechanisms of bone repair and the evolution of material design, highlighting key cellular and molecular processes. It further proposes strategies and prospects for programmable bio‐interactive materials, which enable precisely guided bone tissue regeneration by dynamically regulating cell behavior and the ...
Qingrui Fan, Fuming Cao, Junqiang Mao, Pengbin Yin, Licheng Zhang, Jianjun Wang, Peifu Tang   +6 more
wiley   +1 more source

Oxford Handbook of Orthopaedics and Trauma

, 2010
The Oxford Handbook of Orthopaedics and Trauma offers junior doctors, medical students, and all those with an interest in the field the practical and up-to-date information needed for clinical practice.

core   +1 more source

Engineered Cyanobacteria‐Hydrogel Microecological System for Oxygen Reprogramming Synergizes Immunomodulation With Anabolism in Osteoarthritis Therapy

Advanced Science, EarlyView.
An injectable cyanobacteria‐laden hydrogel enables light‐dependent oxygen metabolism engineering for osteoarthritis therapy. Photosynthetic oxygen release under red light irradiation suppresses synovial inflammation via HIF‐1α inhibition and M2 macrophage polarization, while respiratory oxygen consumption in darkness stabilizes chondrocyte HIF‐1α to ...
Lerong Yang, Chong Shen, Hongjun Huang, Siyi Liu, Zeyu Huang, Licheng Xi, Huan Cao, Li Zheng, Zainen Qin   +8 more
wiley   +1 more source

Orthopaedics and trauma Queensland annual report 2012 [PDF]

, 2013
Orthopaedics and Trauma Queensland, the Centre for Research and Education in Musculoskeletal Disorders, is an internationally recognised research group that continues to develop its reputation as an international leader in research and education.
Izatt, Maree T., Schuetz, Michael, Crawford, Ross W., Woodruff, Maria A., Klein, Travis J., Pearcy, Mark J., Xiao, Yin, Hutmacher, Dietmar, Langton, Christian M.   +8 more
core  

One‐Step Immobilized Phage Depolymerase Coatings for Catheter‐Related Bloodstream Infections

Advanced Science, EarlyView.
Catheter‐related bloodstream infections (CRBSI) caused by drug‐resistant Gram‐negative bacteria remain a major clinical challenge. Here, a polydopamine‐assisted depolymerase coating degrades bacterial capsules and restores serum‐mediated killing, effectively suppressing biofilms and reducing bacterial burden in vitro, ex vivo, and in vivo, presenting a
Lingkai Dong, Xingjin Li, Tao Hu, Qianqian Lu, Xiaoxu Zhang, Xi Chen, Yifan Luo, Zhong Zuo, Ronald Man Yeung Wong, Miao Xu, Tiancong Zhao, Sharon Shui Yee Leung   +11 more
wiley   +1 more source