Results 61 to 70 of about 358,617 (267)

Ion‐Driven Regulation of Ca2+ Flow by Ti/Zn Composite Activates ERK/MAPK Signaling and Maintains Mitochondrial Homeostasis to Promote Macrophage‐Mediated Bone Regeneration

Advanced Science, EarlyView.
A 3D‐printed interpenetrating Ti/Zn composite enables sustained Zn2+ release to regulate intracellular Ca2+ redistribution, preserve mitochondrial homeostasis, activate ERK/MAPK signaling, and promote M2 macrophage polarization, thereby enhancing osteoimmune‐mediated bone regeneration and peri‐implant osseointegration.
Wanyi Huang, Qiyue Zhang, Yueyang Qiu, Haocheng Suo, Zengqian Liu, Bing Bai, Qiang Wang, Qing Zhou   +7 more
wiley   +1 more source

Advances in the Role of Stem Cell-Derived Exosomes in Diabetic Foot Wound Healing

Diabetes, Metabolic Syndrome and Obesity
Junbo Wang,1 Yu-Jie Liang,2 Xiaohua Pan1 1Department of Orthopaedics and Traumatology, The Second Affiliated Hospital of Shenzhen University, Shenzhen, People’s Republic of China; 2The Chinese University of Hong Kong, Hong Kong, People’s Republic of ...
Wang J, Liang YJ, Pan X
doaj  

Regulating Cells Fate and Function to Facilitate Bone Regeneration via Designing Programmable Bio‐Interactive Materials

Advanced Science, EarlyView.
This article aims to elucidate the biological mechanisms of bone repair and the evolution of material design, highlighting key cellular and molecular processes. It further proposes strategies and prospects for programmable bio‐interactive materials, which enable precisely guided bone tissue regeneration by dynamically regulating cell behavior and the ...
Qingrui Fan, Fuming Cao, Junqiang Mao, Pengbin Yin, Licheng Zhang, Jianjun Wang, Peifu Tang   +6 more
wiley   +1 more source

Home Rehabilitation Experience and Influencing Factors in Frail Elderly Patients with Lumbar Spine Surgery: A Qualitative Study

Patient Preference and Adherence
Wei Jiang,1,* Mingyang Qian,1,* Qingsong Zou,1 Xiaowei Chen,2 Mengyi Xu,3 Jiangming Yu3 1Wuxi School of Medicine, Jiangnan University, Wuxi, Jiangsu Province, 214122, People’s Republic of China; 2Kunshan Hospital of Traditional Chinese ...
Jiang W, Qian M, Zou Q, Chen X, Xu M, Yu J   +5 more
doaj  

Liquid Gallium Nanozyme Coatings Enable Sustained Nitric Oxide Generation With Antioxidant and Anti‐Inflammatory Functions

Advanced Science, EarlyView.
Liquid gallium (Ga) acts as a catalytic center for nitric oxide (NO) generation within a tannic acid–zirconium metal–phenolic network coating. Stabilized Ga nanoparticles catalyze S‐nitrosothiol decomposition through surface electron transfer, enabling controlled NO production, enhancing endothelial biocompatibility, and providing antioxidant and anti ...
Franco Centurion, Kang Lin, Shu Geng, Siti Nur Asyura Adzlan, Qingqing Fan, Federico Mazur, Ravindra Kokate, Priyank Kumar, Christina Cortez‐Jugo, Frank Caruso, Rona Chandrawati   +10 more
wiley   +1 more source

Biomimetic Barium Titanate/PLA Scaffold with Shape Memory and Bioelectro-Active Capacities Promotes Bone Regeneration

International Journal of Nanomedicine
Shiyan Lv,1,* Yuechi Zhang,2,* Xiongjie Liang,1,* Wenbo Xu,1 Zhibin Geng,1 Weifeng Hu,1 Xiaoyan Wang,1 Helin Li,1 Wenhui Guo,1 Yongbin Jing,1 Xiaoqi Liu,1 Huichao Fu,1 Gongping Xu,1 Chunyang Xi,1 Jinglong Yan,1 Hui Chi1 ...
Lv S, Zhang Y, Liang X, Xu W, Geng Z, Hu W, Wang X, Li H, Guo W, Jing Y, Liu X, Fu H, Xu G, Xi C, Yan J, Chi H   +15 more
doaj  

A Decoy‐Receptor‐Armed Biomimetic Nanotherapeutic With Inherent Tropism for Conserved Pathogenic Macrophages for Treating Osteoarthritis and Intervertebral Disc Degeneration

Advanced Science, EarlyView.
A biomimetic doppelgänger nanosystem neutralizes extracellular inflammatory cytokines and silences intracellular pyroptosis, reprogramming pathogenic macrophages to attenuate both joint and spine degeneration. ABSTRACT Osteoarthritis (OA) and intervertebral disc degeneration (IVDD) are debilitating musculoskeletal disorders driven by shared ...
Fudong Li, Bin Zhang, Zhiqiu Zhang, Bing Zheng, Linhui Han, Chen Yan, Jialin Li, Kaiqiang Sun, Tianyi Zhao, Jiangang Shi   +9 more
wiley   +1 more source

Multimodal Synergistic Strategies for Diabetic Wound Healing Using Glucose Oxidase Nanocomposites: Therapeutic Mechanisms and Nanomaterial Design

International Journal of Nanomedicine
Zaiwei Fan,1,* Chengzhi Liang,1,* Jiayu Zhang,2,* Yiming Li,3,* Lihua Tan,1 Hui Deng,1 Pinkai Wang,1 Jialiang Wang,1 Jiawei Kang,1 Yudan Zhu,1 Hang Fu,1 Jun Tao1 1Department of Orthopedics, The Second Affiliated Hospital ...
Fan Z, Liang C, Zhang J, Li Y, Tan L, Deng H, Wang P, Wang J, Kang J, Zhu Y, Fu H, Tao J   +11 more
doaj  

Progress in Dentin-Derived Bone Graft Materials: A New Xenogeneic Dentin-Derived Material with Retained Organic Component Allows for Broader and Easier Application

Cells
The optimal repair of rigid mineralized tissues, such as bone, in cases of fracture, surgical resection, or prosthetic placement, is a complex process often necessitating the use of bone graft materials.
Lari Sapoznikov, Martin Humphrey
doaj   +1 more source

Electronic Chip‐Mimetic Medical Implants for Controllable Sonothermal Treatments

Advanced Science, EarlyView.
Inspired by the thermal effect of working electronic chips, which consist of various heterostructures, an sonothermal‐responsive platform has been developed through constructing metal‐semiconductor interface on implants. Biofilm infection and deep vein thrombosis can be successfully treated by controllable ultrasound treatments.
Zhengdong Zhang, Pan Liu, Jie Lei, Shuchang Peng, Qiu Chen, Wei Guan, Yizhou Zhu, Gang Liu, Xiaobo Feng, Cao Yang, Lei Tan   +10 more
wiley   +1 more source