Results 121 to 130 of about 38,397 (303)

ROS‐Responsive Wedelolactone Hydrogel Promotes Intervertebral Disc Repair by Disrupting the NF‐κB–LCN2 Inflammatory Feedback Loop

open access: yesAdvanced Science, EarlyView.
A mechanically robust, ROS‐responsive hydrogel is engineered to treat intervertebral disc degeneration by targeting the NF‐κB–LCN2 inflammatory feedback loop. By delivering wedelolactone specifically within oxidative niches, this system disrupts macrophage–disc cell crosstalk.
Zimei Wu   +10 more
wiley   +1 more source

Comparison between traction-countertraction and modified scapular manipulation for reduction of shoulder dislocation

open access: yesChinese Journal of Traumatology, 2014
Objective:One of the most common joint dislocations presented to the emergency department (ED) is anterior shoulder dislocation (ASD). Various techniques for the treatment of this abnormality have been suggested.
Ghane Mohammad-Reza   +4 more
doaj  

Pearl‐Like Bioinspired Coating Enables Regulation of Mg Degradation for Osteoporotic Bone Repair

open access: yesAdvanced Science, EarlyView.
In this study, inspired by pearl architecture, we developed a layered Ca–P “brick” and Fn‐mimetic peptide “mortar” coating on Mg alloys. The Ca–P layer moderates corrosion and offers mineral cues, while the peptide enhances adhesion and regulates immune‐vascular responses.
Siming Zhang   +12 more
wiley   +1 more source

QUALITY CRITERIA FOR MINIMALLY MANIPULATED BIOTECHNOLOGICAL PRODUCTS BASED ON AUTOLOGOUS BONE MARROW ASPIRATE FOR USE IN TRAUMATOLOGY AND ORTHOPEDICS

open access: yesORTHOPAEDICS TRAUMATOLOGY and PROSTHETICS
Autologous biotechnological products based on bone marrow (BM) are a source of stem cells, in particular, hematopoietic and multipotent mesenchymal stromal cells, and act as one of the alternative therapeutic agents that can slow cartilage degeneration, improve its repair and, ultimately, prevent joint replacement. Objective.
Sergiy Strafun   +5 more
openaire   +2 more sources

Design and motion control of a 6-UPS fully parallel robot for long bone fracture reduction : a thesis presented in partial fulfillment of the requirements for the degree of Master of Engineering in Mechatronics at Massey University [PDF]

open access: yes, 2007
The incidences of long bone fractures in New Zealand are approximately 1 in 10,000. Long bones such as tibia and femur have complicated anatomic structures, making the realignment of these long bone fractures reliant on the skill of the surgeon.
Wu, Yimin
core  

Lactylation Reprogramming in the Bone Infection Microenvironment Identifies PGK1 K361 as a Potential Therapeutic Target for Osteogenic Dysfunction

open access: yesAdvanced Science, EarlyView.
Staphylococcus aureus (S. aureus) infection creates a high‐lactate microenvironment, promoting p300‐mediated lactylation of PGK1 at lysine 361 (K361). Lactylated PGK1 translocates to the mitochondrial outer membrane and interacts with VDAC3. This interaction triggers FtMt downregulation, iron accumulation, and excessive PINK1/Parkin‐mediated mitophagy,
Han‐jun Qin   +5 more
wiley   +1 more source

Minimally invasive double arc osteotomy combined with Chinese bone-setting manipulation for the treatment of hallux valgus

open access: yesZhongguo linchuang yanjiu
Objective To study the clinical efficacy of minimally invasive double arc osteotomy combined with Chinese bone.setting manipulation in the treatment of hallux valgus.
TIAN Li, ZHENG Zhiyong, WANG Zhuang
doaj   +1 more source

Artificial Intelligence for Bone: Theory, Methods, and Applications

open access: yesAdvanced Intelligent Discovery, EarlyView.
Advances in artificial intelligence (AI) offer the potential to improve bone research. The current review explores the contributions of AI to pathological study, biomarker discovery, drug design, and clinical diagnosis and prognosis of bone diseases. We envision that AI‐driven methodologies will enable identifying novel targets for drugs discovery. The
Dongfeng Yuan   +3 more
wiley   +1 more source

Spectrum of arthroscopic findings in 84 canine elbow joints diagnosed with medial compartment erosion [PDF]

open access: yes, 2018
Elbow dysplasia is an important cause of forelimb lameness in large breed dogs. The aim of this study was to report on the arthroscopic findings associated with medial compartment erosion (MCE) of the canine elbow joint.
Broeckx, Bart   +6 more
core  

Sound‐Based Assembly of Magnetically Actuated Soft Robots Toward Enhanced Release of Extracellular Vesicles

open access: yesAdvanced Intelligent Systems, Volume 7, Issue 3, March 2025.
Magnetic soft robots offer promise in biomedicine due to their wireless actuation and rapid response, but current fabrication methods are complex and have limited cellular compatibility. A new, contactless bioassembly strategy using hydrodynamic instabilities is introduced, enabling customizable, centimeter‐scale robots.
Wei Gao   +5 more
wiley   +1 more source

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