Results 191 to 200 of about 95,083 (274)

First‐time cefuroxime target tissue concentrations in long‐lasting spine surgery: Continuous evaluation after repeated weight‐dosed administrations

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Abstract Aims Antimicrobial prophylaxis is central in preventing postoperative spine infections, yet knowledge on clinical target spine tissue concentrations remain limited. Current dosing regimens often involve fixed doses based on empirical knowledge, surrogate measures, non‐clinical evidence and methodology of variying quality.
Magnus Andreas Hvistendahl   +6 more
wiley   +1 more source

Patient, carer and healthcare professional perspectives on deprescribing in surgical wards: A mixed methods study

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Abstract Aims The perspectives of patients and healthcare professionals regarding deprescribing in surgical wards within hospital settings are unknown. The aim of this study was to explore current practices, attitudes and the enablers and barriers to deprescribing in hospital for older surgical inpatients from the perspectives of doctors, pharmacists ...
Bonnie M. Liu   +5 more
wiley   +1 more source

Deciphering the skeletal interoceptive circuitry to control bone homeostasis

open access: yesBMEMat, EarlyView.
This review introduces the skeletal interoceptive circuitry, covering the ascending signals from bone tissues to the brain (sensors), the central neural circuits that integrate this information and dispatch commands (CPU), and the descending pathways that regulate bone homeostasis (effectors).
Yefeng Wu   +7 more
wiley   +1 more source

Lead‐free transparent nanocomposite for efficient clinical X‐ray shielding

open access: yesBMEMat, EarlyView.
A lead‐free nanocomposite of LaF3 nanoparticles exhibits a high optical transparency of 86% with a heavy loading of up to 70 wt%, which enables the design of radiation shielding goggles for interventional surgeons in real clinical scenarios. Abstract The increasing use of X‐ray imaging in the medical field has generated a growing need for efficient ...
Xiangzhou Zhang   +8 more
wiley   +1 more source

One-Year Experience with Day-of-Surgery Pregnancy Testing Before Elective Orthopedic Procedures

open access: bronze, 2008
Richard L. Kahn   +5 more
openalex   +1 more source

Optimizing biophysical properties of cellular niches to enhance stem cell‐derived extracellular vesicle function in musculoskeletal regeneration

open access: yesBMEMat, EarlyView.
Extracellular vesicles (EVs) derived from stem cells show promise for applications in regenerative medicine, but their scalability and yield remain challenges. This review explores the approaches for biophysical modulations within cell niches on EV properties, discusses the current clinical application of EVs, and provides an outlook on the existing ...
Yang Xu   +9 more
wiley   +1 more source

Three‐dimensional assessment of subchondral arc and hip joint coverage angles in the asymptomatic young adult hip

open access: yesClinical Anatomy, EarlyView.
Abstract The primary objective of this study was to develop a custom algorithm to assess three‐dimensional (3D) acetabular coverage of the femoral head based on surface models generated from computed tomography (CT) imaging. The secondary objective was to apply this algorithm to asymptomatic young adult hip joints to assess the regional 3D acetabular ...
Holly D. Aitken   +6 more
wiley   +1 more source

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