Results 191 to 200 of about 4,376,573 (358)
Barnes Hospital Bulletin [PDF]
https://digitalcommons.wustl.edu/bjc_barnes_bulletin/1227/thumbnail ...
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Aged HSF1 muscle‐specific knockout mice show deteriorated muscle atrophy and metabolic dysfunction, while active HSF1 overexpression improves muscle function via activating SIRT3 to deacetylate both PGC1α1 and PGC1α4, which boosts mitochondrial function and muscle hypertrophy in a fiber‐type specific manner, and induces FNDC5/Irisin for tissue ...
Jun Zhang +18 more
wiley +1 more source
Background Pain is a complex experience, associated with several medical and surgical conditions. We aimed to performed initial psychometric evaluation of the Portuguese version of the Glasgow Composite Measure Pain Scale – Short Form (CMPS-SF).
J. C. Alves, Ana Filipe, Ana Santos
doaj +1 more source
RUNX2 Activation in Fibro/Adipogenic Progenitors Promotes Muscle Fibrosis in Muscular Dystrophy
This study revealed a novel role of the chemokine‐TGF‐β1‐RUNX2 axis in determining the fate of FAP differentiation and modulating muscle fibrosis in patients and mice with muscular dystrophies. ABSTRACT Clinical evidence indicates concurrent muscle inflammation and fibrosis in muscular dystrophies (MDs); however, the molecular mechanisms underlying ...
Pengkai Wu +12 more
wiley +1 more source
FSTL1 promotes glycolysis during chondrocyte fibrosis by triggering the HIF‐1 signaling pathway, which causes lactate to accumulate. The buildup of lactate leads to changes in histone lysine lactylation, which in turn enhances the expression of genes associated with fibrosis.
Feng Lu +12 more
wiley +1 more source
Christopher Max Hoshino, John V. Tiberi, and Thomas G. Harris: Orthopedic emergency and office procedures [PDF]
Alain G. Graftiaux
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Study on application of aerospace technology to improve surgical implants [PDF]
The areas where aerospace technology could be used to improve the reliability and performance of metallic, orthopedic implants was assessed. Specifically, comparisons were made of material controls, design approaches, analytical methods and inspection ...
Johnson, R. E., Youngblood, J. L.
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The “gut‐joint axis” in knee synovitis is uncovered. Integrated multi‐omics studies are conducted in two independent osteoarthritis cohorts. Synovitis is characterized an increased F/B ratio, as well as alterations of 3‐HIA, geranic acid, and TWEAK. Upregulated TWEAK receptor is found in high‐grade synovitis, and inversely correlated with lower TWEAK ...
Xiaoshuai Wang +22 more
wiley +1 more source

