Results 231 to 240 of about 4,376,573 (358)

Early Radial Extracorporeal Shockwave Stimulation on Proximal Tibial Circular Osteotomy Site Enhanced Heterotopic Skin Wound Healing via Small Extracellular Vesicles

open access: yesAdvanced Science, EarlyView.
A schematic diagram of the mechanism where small extracellular vesicles mediate the enhancement of heterotopic wound healing by radial extracorporeal shockwave stimulation at a proximal tibial osteotomy site. ABSTRACT Wound healing represents a complex biological process necessitating innovative therapeutic approaches, particularly for chronic wounds ...
Xiaoping Xie   +8 more
wiley   +1 more source

One‐Step Coaxial 3D Printing of Pre‐Vascularized Skin Organoid Models with ADSC Microspheres for Enhanced Wound Healing

open access: yesAdvanced Science, EarlyView.
A multifunctional vascular bed platform is created using coaxial 3D printing, allowing the one‐step integration of organoid microspheres with perfusable vascular structures. This strategy enables rapid and functional vascularization of organoids to support tissue repair and vascularization, providing a scalable and translationally promising approach ...
Kunrui Wang   +10 more
wiley   +1 more source

Osteoclast‐Derived SLIT3 Mediates Osteoarthritis Pain and Degenerative Changes

open access: yesAdvanced Science, EarlyView.
In TMJ‐OA, osteoclasts play a significant role in promoting the growth of sensory nerves at the osteochondral interface. In early OA, TRAP+ osteoclast‐derived SLIT3 induces sensory nerve growth into the condylar cartilage. This nerve growth facilitates the development of pain associated with OA.
Weiwei Zhu   +13 more
wiley   +1 more source

Rescuing Mitochondrial Dysfunction in Macrophages Prevents Osteonecrosis of the Jaw in Anti‐Resorptive Therapy

open access: yesAdvanced Science, EarlyView.
Schematic model showing the suggested mechanism that ZA induces classical activation of macrophages by impairing mitochondrial biofunction and inhibiting mitochondrial clearance to contribute to the pathological process of BRONJ. RAPA‐loaded nanoparticles ZDPR has shown potential in alleviating BRONJ lesions as well as treating osteoporosis or ...
Hang Zhang   +10 more
wiley   +1 more source

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