Results 191 to 200 of about 2,766,444 (332)

Advancements in the Application of the Intersection of Medicine and Engineering in Cancer Research

open access: yesCancer Nexus, EarlyView.
ABSTRACT Cancer research predominantly centers on diagnosis, treatment, and elucidation of underlying mechanisms. Nevertheless, the intricate nature of tumor genesis and development has rendered early diagnostic and therapeutic outcomes less than optimal, making tumor conquest a formidable challenge.
Haitao Chen   +16 more
wiley   +1 more source

CEUS‐assessed supraspinatus muscle perfusion improves after tendon repair and predicts anatomical and functional outcome: A 1‐year prospective pilot study

open access: yesJournal of Orthopaedic Research, Volume 41, Issue 2, Page 426-435, February 2023., 2023
Abstract Rotator cuff tear including SSP (Supraspinatus) tendon tears are a very common and often painful condition with several therapeutic options such as tendon repair. Reflected by the high retear rates, the preoperative selection of patients suitable for surgery or conservative treatment, which often yields comparable results, remains difficult ...
Paul Mick   +4 more
wiley   +1 more source

The effect of enhanced recovery protocols on postoperative rehabilitation in orthopedic surgery patients. [PDF]

open access: yesMedicine (Baltimore)
Cao H   +8 more
europepmc   +1 more source

Metabolic changes during cardiac regeneration in the axolotl

open access: yesDevelopmental Dynamics, EarlyView.
Abstract Background The axolotl is a prominent model organism of heart regeneration due to its ability to anatomically and functionally repair the heart after an injury that mimics human myocardial infarction. In humans, such an injury leads to permanent scarring. Cardiac regeneration has been linked to metabolism and the oxygenation state, but so far,
Anita Dittrich   +10 more
wiley   +1 more source

Age‐, sex‐, and subregion‐specific properties of distal fibular microarchitecture and strength: An ex vivo HR‐pQCT study

open access: yesJournal of Orthopaedic Research, Volume 41, Issue 2, Page 355-363, February 2023., 2023
Abstract Despite its clinical relevance in the context of ankle fractures, little is known about the bone microarchitecture and strength of the distal fibula, especially regarding age‐, sex‐, and subregion‐specific effects. To address this gap of knowledge, we obtained fibulae from 30 skeletally intact donors at autopsy (each 15 male and female), which
Carsten Schlickewei   +7 more
wiley   +1 more source

Assessment of reporting practices and reproducibility potential of a cohort of published studies in computational knee biomechanics

open access: yesJournal of Orthopaedic Research, Volume 41, Issue 2, Page 325-334, February 2023., 2023
Abstract Reproducible research serves as a pillar of the scientific method and is a foundation for scientific advancement. However, estimates for irreproducibility of preclinical science range from 75% to 90%. The importance of reproducible science has not been assessed in the context of mechanics‐based modeling of human joints such as the knee ...
Jason P. Halloran   +13 more
wiley   +1 more source

Inherited metabolic epilepsies–established diseases, new approaches

open access: yesEpilepsia Open, EarlyView.
Abstract Inherited metabolic epilepsies (IMEs) represent the inherited metabolic disorders (IMDs) in which epilepsy is a prevailing component, often determining other neurodevelopmental outcomes associated with the disorder. The different metabolic pathways affected by individual IMEs are the basis of their rarity and heterogeneity.
Itay Tokatly Latzer, Phillip L. Pearl
wiley   +1 more source

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