Results 201 to 210 of about 361,141 (363)

ROS‐Responsive Wedelolactone Hydrogel Promotes Intervertebral Disc Repair by Disrupting the NF‐κB–LCN2 Inflammatory Feedback Loop

Advanced Science, EarlyView.
A mechanically robust, ROS‐responsive hydrogel is engineered to treat intervertebral disc degeneration by targeting the NF‐κB–LCN2 inflammatory feedback loop. By delivering wedelolactone specifically within oxidative niches, this system disrupts macrophage–disc cell crosstalk.
Zimei Wu, Yan Xu, Lang Qin, Zemin Ling, Yingjie Mai, Xiong Tian Guo, Jiajia Chen, Leping Yan, Lin Wang, Liming Bian, Fuxin Wei   +10 more
wiley   +1 more source

A Systematic Review of Temporary Peripheral Nerve Stimulation for Postoperative Pain Management in Orthopedic Surgery. [PDF]

Anesthesiol Res Pract
Harris JC, Pierson CJ, Konda C, Jain NB.
europepmc   +1 more source

Pearl‐Like Bioinspired Coating Enables Regulation of Mg Degradation for Osteoporotic Bone Repair

Advanced Science, EarlyView.
In this study, inspired by pearl architecture, we developed a layered Ca–P “brick” and Fn‐mimetic peptide “mortar” coating on Mg alloys. The Ca–P layer moderates corrosion and offers mineral cues, while the peptide enhances adhesion and regulates immune‐vascular responses.
Siming Zhang, Tao Zhang, Yuan Chen, Nikolaos Kourkoumelis, Mo Chen, Jiale Dong, Zhenyu Li, Yanling Zhou, Ning Li, Chen Zhu, Xifu Shang, Jiaxiang Bai, Xianzuo Zhang   +12 more
wiley   +1 more source

Dysfunctional personality traits and body image in orthopedic surgery patients at risk of postoperative psychological distress. [PDF]

Sci Rep
Brzezewska K, Walenista W, Starosta J, Lizińczyk S, Bandura A, Bernasik-Smagała Z, Dutka J, Izydorczyk B.   +7 more
europepmc   +1 more source

THROMBOPROPHYLAXIS IMPACT IN PATIENTS UNDERGOING MAJOR ORTHOPEDIC SURGERY IN SUDAN

, 2020
Abubaker Aldosh, Kholoud Hamad, Ali Hashim, Aziza Mohammed, Osman Babiker, Ali Awadallah Saeed, Mohamed Awad Mousnad   +6 more
openalex   +2 more sources

CGRP Enhances the Regeneration of Bone Defects by Regulating Bone Marrow Mesenchymal Stem Cells Through Promoting ANGPTL4 Secretion by Bone Blood Vessels

Advanced Science, EarlyView.
ABSTRACT Bone angiogenesis is important for bone formation and regeneration after bone injury. Endothelial‐derived angiogenic factors are key signal transducers in the bone microenvironment and maintain vascular–osteogenic coupling during bone regeneration.
Qiong Lu, Qiyue Zheng, Zhaokai Zhou, Yajun Chen, Yun Chen, Wenjie Chen, Jiaojiao Wang, Ren Guo, Ren Wu, Lina Chen   +9 more
wiley   +1 more source

Editorial: Harnessing artificial intelligence for multimodal predictive modeling in orthopedic surgery. [PDF]

Front Surg
Saravi B, Couillard-Despres S, Lang G, Hassel F.   +3 more
europepmc   +1 more source

1941 Commencement for Jefferson Medical College [PDF]

, 1941

core   +1 more source

Artificial Intelligence for Bone: Theory, Methods, and Applications

Advanced Intelligent Discovery, EarlyView.
Advances in artificial intelligence (AI) offer the potential to improve bone research. The current review explores the contributions of AI to pathological study, biomarker discovery, drug design, and clinical diagnosis and prognosis of bone diseases. We envision that AI‐driven methodologies will enable identifying novel targets for drugs discovery. The
Dongfeng Yuan, Haicang Zhang, Liping Tong, Di Chen   +3 more
wiley   +1 more source

Does perioperative discontinuation of anti-rheumatic drugs increase postoperative complications in orthopedic surgery for rheumatoid arthritis? [PDF]

Arthritis Res Ther
Ito H, Ishikawa H, Tsuji S, Nakayama M, Nishida K, Mochizuki T, Ebina K, Kojima T, Matsumoto T, Kubota A, Nakajima A, Kaneko A, Matsushita I, Hara R, Sakuraba K, Akasaki Y, Matsubara T, Mochida Y, Kanbe K, Nakagawa N, Murata K, Momohara S.   +21 more
europepmc   +1 more source