Results 141 to 150 of about 266,380 (370)

Effect of low temperatures on osserous and cartilaginous tissues [PDF]

The use of extreme cold to treat tumoral afflictions of the extremities is discussed. Cryogenic methods and instruments are discussed, and the levels of accumulated knowledge in this area (as well as the areas still in question) are evaluated.
Babiychuk, G. A., Malyshkina, S. V., Pankov, Y. Y., Zhigun, A. I.   +3 more
core   +1 more source

Regulating PPARG Reduces Lipid Accumulation in Microglia and Promotes Functional Recovery After Spinal Cord Injury

Advanced Science, EarlyView.
Macrophages infiltrate the spinal cord post‐injury, decreasing over time. Microglia phagocytose myelin debris, increasing lipid accumulation. Macrophage deletion improves outcomes, while microglial deletion worsens them. The LD+ microglia subtype shows abnormal Pparg signaling.
Mingran Luo, Jiayun Liu, Yunxin Su, Tao Jiang, Xincan Wu, Peng Gao, Tao Qin, Mengyuan Wu, Qingqing Li, Shujun Zhang, Baorong He, Yongxiang Wang, Xiaodong Guo, Wei Zhou, Shujie Zhao, Jin Fan, Jian Chen, Guoyong Yin   +17 more
wiley   +1 more source

Artificial intelligence in orthopedics: three strategies for deep learning with orthopedic specific imaging

Knee Surgery, Sports Traumatology, Arthroscopy, 2022
Sunho Ko, Ayoosh Pareek, D. Ro, Yining Lu, Christopher L. Camp, R. K. Martin, A. Krych   +6 more
semanticscholar   +1 more source

Cancer Neuroscience: Decoding Neural Circuitry in Tumor Evolution for Targeted Therapy

Advanced Science, EarlyView.
This review highlights the pivotal role of the nervous system in cancer progression, emphasizing how neural–tumor interactions—via synaptic signaling, neurotransmitters, and paracrine factors—reshape the tumor microenvironment. It introduces cancer neuroscience as an emerging field and proposes integrating advanced tools such as AI and optogenetics to ...
Mengyu Yuan, Rongjiao Xi, Yong Kang, Ming‐jie Kuang, Xiaoyuan Ji   +4 more
wiley   +1 more source

More and better orthopedics in the year 2000 [PDF]

, 1991

openalex   +1 more source

Patients‐Derived Organoids Sequencing‐based FOXP4 Facilitates Radioresistance by Transcriptionally Modifying GPX4 to Regulate ferroptosis in Colorectal Cancer

Advanced Science, EarlyView.
FOXP4 regulates GPX4 transcription to suppress ferroptosis. In CRC patients, initial biopsies established PDO cultures alongside concurrent chemoradiotherapy. Post‐treatment MRI with mrTRG scoring stratified radioresistant/sensitive cohorts. Parallelly, 8Gy‐irradiated PDOs underwent viability‐based stratification.
Qianping Chen, Yuzhao Jin, Luyu Liao, Rong Shen, Xingnan Ge, Qingyu Jiang, Ying Huang, Quanquan Sun, Dong Liu, Luying Liu, Tongxin Liu, Qinghui Dai, Xiyuan Tang, Zhe Han, Xin Gao, Xinhua Lin, Wei Mao, Ji Zhu   +17 more
wiley   +1 more source

Language Skills of Young Children With Unilateral Cleft Lip and Palate Following Infant Orthopedics: A Randomized Clinical Trial [PDF]

, 2003
Emmy M. Konst, Toni Rietveld, Herman F.M. Peters, Anne Marie Kuijpers‐Jagtman   +3 more
openalex   +3 more sources

Half‐Pipe Melt Electrowritten Scaffolds Support Engineering of an Immunocompetent Hydrogel‐Embedded Intestine‐on‐a‐Chip

Advanced Science, EarlyView.
The immunocompetent Intestine‐on‐a‐Chip (IoC) is developed using melt electrowritten (MEW) half‐pipes. Intestinal epithelial cell (IEC) culture is optimized in the MEW‐based IoC, followed by co‐culture with monocyte‐derived dendritic cells (moDCs) and T cells in 3D hydrogels.
Robine Janssen, Henrike S. Schulze, Claire M. L. Nelissen, Marta G. Valverde, Andrei Hrynevich, Govardus A. H. de Jong, Anne Metje van Genderen, Jos Malda, Shanna Bastiaan‐Net, Linette E. M. Willemsen, Rosalinde Masereeuw   +10 more
wiley   +1 more source

Orthobiologic Management Options for Degenerative Disc Disease

Bioengineering
Degenerative disc disease (DDD) is a pervasive condition that limits quality of life and burdens economies worldwide. Conventional pharmacological treatments primarily aimed at slowing the progression of degeneration have demonstrated limited long-term ...
Cezar Augusto Alves de Oliveira, Bernardo Scaldini Oliveira, Rafael Theodoro, Joshua Wang, Gabriel Silva Santos, Bruno Lima Rodrigues, Izair Jefthé Rodrigues, Daniel de Moraes Ferreira Jorge, Madhan Jeyaraman, Peter Albert Everts, Annu Navani, José Fábio Lana   +11 more
doaj   +1 more source

Ultrasound in the diagnosis of clinical orthopedics: The orthopedic stethoscope

World Journal of Orthopedics, 2011
Ultrasonography has advantages over other imaging modalities in terms of availability and comfort, safety, and diagnostic potential. Operating costs are low compared with both computed tomography (CT) and magnetic resonance imaging (MRI). The portable equipment is accessible at locations distant from medical centers.
openaire   +3 more sources