Functional Dendrimer Nanogels for DNA Delivery and Gene Therapy of Tumors
Angewandte Chemie, EarlyView.Dendrimer nanogels are designed by emulsion‐free method, endowing them with dual‐active groups, o‐hydroxyl amine, temperature‐responsiveness, polyampholyte property, and self‐triggered aminolysis. With these unique characters, dendrimer nanogels display high gene transfection and therapeutic efficacies with low side effects, thus solving the dilemma ...
Xin Li +7 more
wiley +2 more sources
Enhanced Knee Kinematics: Leveraging Deep Learning and Morphing Algorithms for 3D Implant Modeling [PDF]
arXivAccurate reconstruction of implanted knee models is crucial in orthopedic surgery and biomedical engineering, enhancing preoperative planning, optimizing implant design, and improving surgical outcomes. Traditional methods rely on labor-intensive and error-prone manual segmentation.
arxiv
Isolation of Acanthamoeba isolates belonging to T2, T3, T4 and T7 genotypes from environmental samples in Ankara, Turkey [PDF]
, 2004 Acanthamoeba keratitis is a blinding infection that is becoming increasingly important in human health. Early diagnosis is a prerequisite for successful treatment and requires identification of Acanthamoeba at the genotypic level.
Jayasekera, S. +4 more
core
Phonological Development of Toddlers With Unilateral Cleft Lip and Palate Who Were Treated With and Without Infant Orthopedics: A Randomized Clinical Trial [PDF]
, 2003 Emmy M. Konst +3 more
openalex +1 more source
Advanced Intelligent Systems, EarlyView.A machine learning approach utilizes micro inertial measurement units (μIMUs) for noninvasive sarcopenia screening through a sit‐to‐stand test. With 53 older participants wearing IMUs, 510 features are extracted across four motion phases. Five algorithms (support vector machine, K‐nearest neighbors, decision tree, linear discriminant analysis, and ...
Keer Wang +11 more
wiley +1 more source
StraightTrack: Towards Mixed Reality Navigation System for Percutaneous K-wire Insertion [PDF]
arXivIn percutaneous pelvic trauma surgery, accurate placement of Kirschner wires (K-wires) is crucial to ensure effective fracture fixation and avoid complications due to breaching the cortical bone along an unsuitable trajectory. Surgical navigation via mixed reality (MR) can help achieve precise wire placement in a low-profile form factor.
arxiv
Investigation of Force Decay in Aesthetic, Fibre-Reinforced Composite Orthodontic Archwires [PDF]
, 2015 Background/Objectives: Because polymer-based materials typically exhibit viscoelastic properties, the objective was to determine if commercially available, aesthetic, fibre-reinforced composite archwires maintain continuous forces without undergoing ...
Ballard, Richard W. +3 more
core +1 more source
Children With 22.Q.11.2 Deletion Syndrome: Sleep‐Disordered Breathing and Management
American Journal of Medical Genetics Part A, EarlyView.ABSTRACT Patients with 22q11.2 deletion syndrome (22q11DS) are predisposed to obstructive sleep apnea (OSA) due to an abnormal craniofacial anatomy with pharyngeal hypotonia, retrognathia, micrognathia, and glossoptosis. The aim of the study was to describe the prevalence and management of OSA in a cohort of children with 22q11DS.
Domenico Paolo La Regina +6 more
wiley +1 more source
Acquiring Submillimeter-Accurate Multi-Task Vision Datasets for Computer-Assisted Orthopedic Surgery [PDF]
arXivAdvances in computer vision, particularly in optical image-based 3D reconstruction and feature matching, enable applications like marker-less surgical navigation and digitization of surgery. However, their development is hindered by a lack of suitable datasets with 3D ground truth.
arxiv