Results 241 to 250 of about 252,274 (340)

Impact of Denosumab Adherence on Renal Function and Mortality Rates in Type 2 Diabetes Patients With Osteoporosis

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Type 2 diabetes mellitus (T2DM) is associated with an increased risk of osteoporosis and fractures, and denosumab, a non‐kidney‐excreted antiresorptive medication, represents a viable alternative to bisphosphonates for osteoporosis treatment in patients with T2DM. This study aimed to investigate the association among denosumab adherence, renal
Yu‐Chuan Chang, Jian‐Chih Chen, Sung‐Yen Lin, Kun‐Der Lin, Pei‐Shan Ho, Chung‐Hwan Chen, Yin‐Chih Fu, Tien‐Ching Lee   +7 more
wiley   +1 more source

Melatonin Exerts Chondroprotective Effects Against Osteoarthritis by Promoting PI3K/AKT/FoxO3‐Mediated Mitophagy

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Osteoarthritis (OA) is a prevalent degenerative joint disease. This study combines bioinformatics analysis with in vivo and in vitro experiments to elucidate the molecular mechanisms through which melatonin (MT) regulates mitophagy to alleviate OA.
Chao Huang, Gang Zhang, Ying‐Kai Ma, Xin‐Nan Ma, Song‐Cen Lv   +4 more
wiley   +1 more source

Valproic Acid Inhibits Ferroptosis and Improves Bone Integration in OVX Rats Through the AMPK/SIRT1 Pathway

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT The prevalence of postmenopausal osteoporosis (PMOP) has been steadily increasing. Ferroptosis has been recognized as a critical factor influencing the bone‐forming ability of bone marrow mesenchymal stem cells (BMSCs). Valproic acid (VPA), an HDAC inhibitor, has been suggested to play a role in regulating osteoporosis development; however ...
Qing‐Song Gu, Yi‐Fan Gu, Jian‐Qiao Li, Yi‐Heng Li, Yu‐Hu Chen, Lin‐Hui Wang, Zi‐Ru Wang, Yi‐Cong Wang, Min Yang   +8 more
wiley   +1 more source

Extracellular Vesicle‐Mediated Communication Between Anterior Cruciate Ligament and Bone Marrow Cells Modulates Hamstring Tenocyte Behavior and Apoptosis

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Following anterior cruciate ligament (ACL) reconstruction, enhancing hamstring tenocyte activity and minimizing apoptosis are critical for preventing graft failure and promoting ligamentization. This study investigated the therapeutic potential of extracellular vesicles (EVs) derived from a coculture of ACL remnant cells and bone marrow ...
Hon‐Lok Lo, Shih‐Hao Huang, Ting‐Hsuan Dai, Shun‐Cheng Wu, Cheng‐Jung Ho, Cheng‐Chang Lu   +5 more
wiley   +1 more source

Bent not broken

Journal of Hospital Medicine, EarlyView.
Rogie Gabrielle
wiley   +1 more source

Several flat tendon graft types are viable options for flat superficial medial collateral ligament reconstructions—A biomechanical analysis

Knee Surgery, Sports Traumatology, Arthroscopy, EarlyView.
Abstract Purpose Flat superficial medial collateral ligament (sMCL) reconstruction helps restore knee kinematics in medial instability, but recommendations on grafts that best mimic the sMCL's biomechanical properties are missing. This study aimed to compare the biomechanical properties of flat grafts to the native sMCL, hypothesizing that (1) flat ...
Thorben Briese, Christian Peez, Philipp Runde, Matthias Klimek, Adrian Deichsel, Michael J. Raschke, Christoph Kittl, Elmar Herbst   +7 more
wiley   +1 more source

Treatment of large chondral lesions with an autologous minced cartilage technique and synovial flap leads to superior results compared to matrix associated autologous chondrocyte transplantation technique after 24 months: A controlled clinical trial

Knee Surgery, Sports Traumatology, Arthroscopy, EarlyView.
Abstract Purpose Treating large cartilage lesions in the knee remains a challenge. While matrix‐associated autologous chondrocyte implantation (MACI) is the gold standard for medium to large lesions, the minced cartilage technique has shown promise in smaller defects. Enhancing this technique with biomaterials has been suggested for larger lesions, but
Johanna Mayr, Franziska Warth, Nicola Oehler, Martin Majewski, Christoph Lutter, Fabian Blanke   +5 more
wiley   +1 more source

Preserving scientific integrity in academic publishing: Navigating artificial intelligence, journal policies and the impact factor as a quality indicator

Knee Surgery, Sports Traumatology, Arthroscopy, EarlyView.
Abstract The integration of artificial intelligence (AI), the rise of mega‐journals, and the manipulation of impact factors present challenges to scientific integrity. These trends threaten the core principles of objectivity, reproducibility, and transparency.
Mahmut Enes Kayaalp, Stefano Zaffagnini, Michael A. Mont, Jon Karlsson, Bruce Reider, Olufemi Ayeni, Thomas Heyse, Henning Madry, Elmar Herbst, Giuseppe Milano, Volker Musahl, Roland Becker, Michael T. Hirschmann   +12 more
wiley   +1 more source

Correction: Serological risk factors for steroid-induced osteonecrosis in HIV men: a Bayesian case-control study. [PDF]

Front Med (Lausanne)
Ji Y, Li K, Zhao R, Zhao C, Zhang Q.
europepmc   +1 more source

CERAMICS AND METALS IN ORTHOPEDICS: ADVANTAGES AND DISADVANTAGES OF BIOMATERIALS IN ENDOPROSTHESES

Doriana Agop Forna, Laura Elisabeta Checheriță, Lawrence Chukwudi NWABUDIKE   +2 more
openalex   +1 more source