Results 211 to 220 of about 46,140 (282)

Meniscus extrusion assessed by ultrasound does not correlate with knee function or radiographic signs of joint degeneration after medial and lateral meniscus allograft transplantation at a mean follow‐up of 13 years

open access: yesKnee Surgery, Sports Traumatology, Arthroscopy, EarlyView.
Abstract Purpose The aim of this study was to assess meniscus extrusion using ultrasound after meniscus allograft transplantation (MAT) and its association with clinical outcomes. Methods Patients who underwent medial or lateral MAT with a minimum 5‐year follow‐up were included. Exclusion criteria included bilateral MAT.
Anja M. Wackerle   +9 more
wiley   +1 more source

Effect of video‐based game therapy on activation of scapular muscles in children with thoracic hyperkyphosis

open access: yesPM&R, EarlyView.
Abstract Background Game‐based rehabilitation has been shown to support motor control and muscle activation in children; therefore, video‐based gaming may represent a promising rehabilitation approach for targeting scapular muscles. Objective To examine the effects of video‐based game therapy on scapular muscle activation, strength, and upper extremity
Kubra Kardes   +2 more
wiley   +1 more source

Purpurin Alleviates Meniscal Senescence and Osteoarthritis by Blocking the Non‐Metabolic Function of Hexokinase 2

open access: yesCell Proliferation, EarlyView.
HK2 is upregulated in osteoarthritis and accelerates disease progression via a glycolysis‐independent non‐metabolic mechanism. It recruits PRKN to degrade MYH10, reducing COL1A1 mRNA stability and inducing senescence. Purpurin disrupts this pathogenic pathway with therapeutic potential.
Zhencan Lin   +9 more
wiley   +1 more source

Ηip dysplasia in children with spina bifida after prenatal surgical closure

open access: yesDevelopmental Medicine &Child Neurology, EarlyView.
Neonatal hip morphology following prenatal closure remains poorly characterized. This study is the first to compare the prevalence of sonographically detectable hip dysplasia in children who underwent prenatal closure for spina bifida with that of the general infant population.
Domenic Grisch   +38 more
wiley   +1 more source

Working‐life expectancy in people with cerebral palsy in Finland

open access: yesDevelopmental Medicine &Child Neurology, EarlyView.
In this study we estimated the working‐life expectancy (WLE) of people with CP compared to people without CP by calculating WLE and transition probabilities between working and non‐working and to dead. Abstract Aim To estimate the working‐life expectancy (WLE) of people with cerebral palsy (CP) compared with people without CP in Finland.
Ira Jeglinsky‐Kankainen   +4 more
wiley   +1 more source

Influence of carbonate apatite nanoparticles incorporated into commercial dental adhesives on immediate and long‐term microtensile bond strength

open access: yesEuropean Journal of Oral Sciences, EarlyView.
Abstract This study assessed whether integrating carbonate apatite nanoparticles with a CO3/PO4 molar ratio of 5 (CA5n) into commercial adhesives affected the immediate or the long‐term microtensile bond strength (µTBS) between composite resin and dentin.
Heba E. AbdelRazik   +2 more
wiley   +1 more source

Italian Patients Journey for Gene Therapy in Haemophilia A

open access: yesHaemophilia, EarlyView.
ABSTRACT Introduction Gene therapy (GT) provides sustained FVIII levels without repeated infusions in Hemophilia A (HA) patients thus overcoming a major limitation of replacement therapy. However, issues remain e.g., patient selection criteria, duration and variability of transgene expression, quality of life and long‐term safety.
Giovanni Di Minno   +19 more
wiley   +1 more source

A Common Language for the Multidisciplinary Team: Point‐of‐Care Musculoskeletal Ultrasound in Modern Haemophilia Care

open access: yesHaemophilia, EarlyView.
ABSTRACT The evolving haemophilia care landscape has evolved with personalised prophylaxis, new coagulation factor molecules, non‐replacement therapies, and gene therapy, leading to significantly reduced bleeding frequency and haemophilic arthropathy burden.
Hortensia De la Corte‐Rodriguez   +16 more
wiley   +1 more source

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