Results 51 to 60 of about 46,140 (282)

Letters to the editor

Revista Colombiana de Ortopedia y Traumatología, 2012
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Germán Valcárcel-Torres, Rolando Espitia, Eduardo Reina, Gabriel Ochoa del Portillo, Mónica María Sánchez Vargas, Carlos Almeida Herdoiza, Gustavo Múnera Bohórquez   +6 more
doaj  

Persistent Zn2+ Influx‐Mediated Deacetylation of ANXA2 Regulates the “Zn2+‐Autophagic Flux” and Alleviates Intervertebral Disc Degeneration

Advanced Science, EarlyView.
Zinc transporter SLC39A14 sustains intracellular Zn2+ levels to activate SIRT3‑dependent ANXA2 deacetylation at K302. This modification weakens ANXA2‑mTOR binding and releases autophagic‑flux suppression in nucleus pulposus cells. Dysregulated Zn2+ homeostasis disrupts this axis to drive intervertebral disc degeneration.
Yuxin Jin, Yongcheng Chen, Yihao Xie, Dongyang Hu, Longhui Gong, Zhihua Chen, Linjie Chen, Minhao Gao, Qizhu Chen, Morgan Jones, Hui Wang, Xiuling You, Kenny Yat Hong Kwan, Shoutao Weng, Taidong Lyu, Xiang Chen, Yuxiao Zhu, Yusheng Wang, Bin Li, Xiangyang Wang, Xiaofeng Jia, Kailiang Zhou, Ouqiang Wu, Aimin Wu   +23 more
wiley   +1 more source

Efficiency of multimodal anаlgesia in orthopedics and traumatology

Медицина болю, 2019
Проведене клінічне дослідження на 200 пацієнтах, яким в умовах ортопедо­травматологічного стаціонару виконувалось тотальне ендопротезування кульшового та колінного суглобів, а також металоостеосинтез довгих кісток нижніх кінцівок.
Oleksii Kalashnykov, Yurii Stavynskyi, Kostiantyn Vdovichenko, Andrii Kalashnykov   +3 more
doaj   +1 more source

Application of fuzzy TOPSIS method in pseudoarthrosis treatment with stem cells

Revista Información Científica, 2023
Introduction: currently there are very few published studies concerning the effect of implantations with stem cells in post-surgical aseptic pseudoarthrosis.
Greister Díaz-Schery, Niovis Romero-Ramírez, Miguel Velázquez-Hernández   +2 more
doaj   +1 more source

STING/Type I Interferon Pathway Activation Confers Multimodal Therapeutic Benefits in Osteomyelitis

Advanced Science, EarlyView.
STING/type I interferon signaling counteracts osteomyelitis through coordinated control of pain, bone destruction, and abscess formation. It inhibits pathogen‐induced nociceptor activation, restrains osteoclast‐mediated bone resorption, and suppresses IL‐1β‐driven neutrophil recruitment.
Yang Chen, Jianhua Lv, Yuanqing Cai, Xuhui Yuan, Hongxin Hu, Jiayu Li, Yiming Lin, Hongyan Li, Lan Lin, Huangfeng Lin, Chaofan Zhang, Qijin Wang, Ying Huang, Zida Huang, Wenbo Li, Susheng Niu, Jianhua Lin, Bin Yang, Xinyu Fang, Wenming Zhang   +19 more
wiley   +1 more source

Orthopaedics and Traumatology in COVID-19 Pandemic

, 2021
Objectives:We aimed to convey our pandemic observations and experience as orthopedics and traumatology clinic in the period from the formal declaration of the first case in Turkey to the descending trend of the number of active cases.Materials and ...
Mustafa Özyıldıran, Mahmut Kalem, Abdullah Merter, Mustafa Onur Karaca, Kerem Başarır, Hüseyin Yusuf Yıldız, Ramazan Akmeşe, Bülent Erdemli, Emre Anıl Özbek, Hakan Kınık, Mehmet Armangil, Hakan Kocaoğlu   +11 more
core   +1 more source

Yoda1‐Functionalized Nanozymes Coordinate Piezo1 Activation and Mitochondrial Protection to Reprogram the Diabetic Osteoimmune Micromilieu and Promote Vascularized Bone Repair

Advanced Science, EarlyView.
Diabetic bone defects remain a critical clinical challenge. A 3D‐printed BCPG‐MF@Y scaffold, embedding Yoda1‐functionalized manganese dioxide‐ferritin nanozymes, scavenges mtROS, suppresses the cGAS–STING pathway, and reverses cellular senescence, while Yoda1 activates Piezo1 to direct BMSCs fate to synergistically reprogram the osteoimmune ...
Qing‐Song Deng, Ang Wang, Ren Zhang, Xu‐Ran Li, Po‐Lin Liu, Shu‐Hang He, Zi‐Yin Han, Zhi‐Han Shen, Zhan‐Ying Wei, Chang‐Ru Zhang, Fei Wang, Helen Dawes, Jian Lu, Tong‐He Zhu, Jin‐Zhong Zhao, Shang‐Chun Guo, Shi‐Cong Tao   +16 more
wiley   +1 more source

VREDEN RUSSIAN RESEARCH INSTITUTE OF TRAUMATOLOGY AND ORTHOPEDICS

Travmatologiâ i Ortopediâ Rossii, 2017
Currently, the use of bone allografts for reconstructive orthopedic surgery in clinical practice around the world is becoming a common procedure. Bone allografts are the first substitute material to the autologous bone and the best alternative to any ...
K. A. Vorobyоv, S. A. Bozhkova, R. M. Tikhilov, A. Zh. Cherny   +3 more
doaj   +1 more source

Histological analysis of the spatio‐temporal development of porcine knee cartilage in embryonic and early postnatal stages

Animal Models and Experimental Medicine, EarlyView.
This study dynamically charts the developmental process of the knee joint cartilage from the embryonic stage through to postnatal life, revealing key developmental events including the origin of knee joint development, chondrification, primary ossification, secondary ossification, formation of the cartilage cancal, and formation of the growth plate. It
Yan Nie, Kai Wang, Xuewen Wang, Jinzhu Jing, Zhen Liang, Guoqiang Yan, Wen Feng Guo, Meng Zhang, Wei Zhang, Lei Xiang   +9 more
wiley   +1 more source

Capsular Repair During Hip Arthroscopy for Femoroacetabular Impingement Syndrome Improves Revision Rates and Hip Outcome Score Result but Not Overall Patient‐Reported Outcomes: A Systematic Review and Meta‐analysis of Randomized Clinical Trials

Arthroscopy, EarlyView.
Purpose To determine whether capsular repair (CR) after hip arthroscopy for femoroacetabular impingement syndrome provides superior clinical outcomes, functional recovery, and complication profiles compared with nonrepair. Methods Following the Preferred Reporting Items for Systematic Reviews and Meta‐Analyses guidelines, a search of PubMed, Scopus ...
Riccardo Giai Via, Francesco Bosco, Ahmed Elzeiny, Alessandro Dario Lavia, Matteo Giachino, Alessandro Massè, Nicolas Bonin   +6 more
wiley   +1 more source