Results 221 to 230 of about 11,628 (248)
Some of the next articles are maybe not open access.
2004
Biologic and antigenic properties are often useful for identifying and differentiating orthopoxviruses (OPV). However, polymerase chain reaction (PCR) amplification, with either restriction cleavage or sequencing of amplicons, has been gaining credibility as a more rapid, specific, sensitive, and often cost-saving technique for research and diagnostic ...
Hermann, Meyer +2 more
openaire +2 more sources
Biologic and antigenic properties are often useful for identifying and differentiating orthopoxviruses (OPV). However, polymerase chain reaction (PCR) amplification, with either restriction cleavage or sequencing of amplicons, has been gaining credibility as a more rapid, specific, sensitive, and often cost-saving technique for research and diagnostic ...
Hermann, Meyer +2 more
openaire +2 more sources
1990
Genetic analysis of orthopoxviruses has contributed substantially to our understanding of the functional organization of the poxvirus genome, and individual mutants provide invaluable tools for future studies of poxvirus biology. Deletion and transposition mutants, localized primarily in the termini of the genome, may be particularly useful for ...
R C, Condit, E G, Niles
openaire +2 more sources
Genetic analysis of orthopoxviruses has contributed substantially to our understanding of the functional organization of the poxvirus genome, and individual mutants provide invaluable tools for future studies of poxvirus biology. Deletion and transposition mutants, localized primarily in the termini of the genome, may be particularly useful for ...
R C, Condit, E G, Niles
openaire +2 more sources
Orthopoxvirus infection among wildlife in Zambia
Journal of General Virology, 2015(Uploaded by Plazi for the Bat Literature Project) Human monkeypox is a viral zoonosis caused by monkeypox virus, an orthopoxvirus (OPXV). The majority of human monkeypox cases have been reported in moist forested regions in West and Central Africa, particularly in the Democratic Republic of the Congo (DRC).
Orba, Yasuko +10 more
openaire +3 more sources
Animal Models of Orthopoxvirus Infection
Veterinary Pathology, 2010Smallpox was one of the most devastating diseases known to humanity. Although smallpox was eradicated through a historically successful vaccination campaign, there is concern in the global community that either Variola virus (VARV), the causative agent of smallpox, or another species of Orthopoxvirus could be used as agents of bioterrorism. Therefore,
J L, Chapman +3 more
openaire +2 more sources
Genus Orthopoxvirus: Monkeypox virus
2007Monkeypox virus is an orthopoxvirus that is genetically distinct from other members of the genus, including Variola virus, Vaccinia virus, Ectromelia virus, Camelpox virus, and Cowpox virus. It was first identified as the cause of a pox-like illness in captive monkeys in 1958.
Sandra Essbauer, Hermann Meyer
openaire +1 more source
Genus Orthopoxvirus: Cowpox virus
2007Cowpox virus (CPXV) is distinguished from other orthopoxvirus (OPV) species by producing cytoplasmic A-type inclusion bodies and flattened pocks with a hemorrhagic center on the chorioallantoic membrane. CPXV is endemic to Western Eurasia and naturally infects a broad range of host species including domestic animals, and zoo animals, as well as humans.
Sandra Essbauer, Hermann Meyer
openaire +1 more source
Smallpox and Other Orthopoxvirus Diseases
VacciTUTOR, 2022Smallpox was a severe disease causing substantial mortality among populations over several thousand years. It is caused by an orthopoxvirus, the variola (= smallpox) virus. Smallpox is a febrile disease with a maculo-, papulo-, vesicular and finally pustular rash, the typical pox lesions, numerous complications and a fatality rate of approximately 30%.
openaire +1 more source
Pharmacological Review on Orthopoxvirus
Research Journal of Pharmacology and PharmacodynamicsMonkeypox is an emerging viral zoonotic disease caused by the monkeypox virus, which is particularly significant as it is endemic to Central and Western Africa. This disease is rare and manifests with a rash resembling that of smallpox. However, its transmission between individuals beyond close contact is limited, and the case fatality rates for ...
P. Devi Guna Sireesha +4 more
openaire +1 more source
Regulation of Orthopoxvirus Gene Expression
1990Poxviruses differ from the other major groups of DNA viruses with regard to their use of the cytoplasm, rather than the nucleus, as the site of transcription. Consistent with this strategy, poxviruses encode their own DNA-dependent RNA polymerase as well as many—if not all—of the additional enzymes and factors needed to synthesize functional capped ...
openaire +2 more sources
Orthopoxvirus vaccines and vaccination
2007Immunization procedures against Variola virus, from the historical perspective most often first credited to Edward Jenner in the late 18th century, helped finally to eradicate smallpox from the world. Since its eradication, the study of this disease and its pathology has been given little attention; however, with the emergence of Monkeypox virus into ...
Lauren M. Handley +3 more
openaire +1 more source