Results 111 to 120 of about 18,551 (298)

Central Involvement in Pure Autonomic Failure: Insights from Neuromelanin‐Sensitive Magnetic Resonance Imaging and 18F‐Fluorodopa‐Positron Emission Tomography

open access: yesMovement Disorders, EarlyView.
Abstract Background Central synucleinopathies, including Parkinson's disease (PD), dementia with Lewy bodies (DLB), and multiple system atrophy (MSA), involve alpha‐synuclein accumulation and dopaminergic cell loss in the substantia nigra (SN) and locus coeruleus (LC).
Paula Trujillo   +10 more
wiley   +1 more source

The Postural Tachycardia Syndrome (POTS): Pathophysiology, Diagnosis & Management [PDF]

open access: yes, 2006
Postural tachycardia syndrome (POTS), characterized by orthostatic tachycardia in the absence of orthostatic hypotension, has been the focus of increasing clinical interest over the last 15 years 1. Patients with POTS complain of symptoms of tachycardia,
Raj, Satish R
core   +1 more source

Self‐Reported Motor and Nonmotor Symptoms, Prodromal Parkinson's Disease Probability, and Incident Parkinson's Disease in US Farmers

open access: yesMovement Disorders, EarlyView.
Abstract Background Few studies have assessed motor and nonmotor symptoms and the prodromal probability of Parkinson's disease (PD) among farming populations. Objective The aim was to assess self‐reported nonmotor and motor symptoms and the prodromal PD probability in relation to incident PD among US farmers.
Shengfang Song   +10 more
wiley   +1 more source

Postprandial Hypotension due to a Lack of Sympathetic Compensation in Patients with Diabetes Mellitus. [PDF]

open access: yes, 2007
Postprandial hypotension is an important hemodynamic abnormality in diabetes mellitus, but few reports are available on the relationship between autonomic dysfunction and postprandial hypotension.
Katayama, Yusuke   +7 more
core   +1 more source

Clinical presentation and long-term follow-up of dopamine beta hydroxylase deficiency [PDF]

open access: yes, 2020
Dopamine beta hydroxylase (DBH) deficiency is an extremely rare autosomal recessive disorder with severe orthostatic hypotension, that can be treated with L-threo-3,4-dihydroxyphenylserine (L-DOPS).
Deinum, Jaap   +13 more
core   +2 more sources

The Proportion of Orthostatic Hypotension and Its Relationship with HbA1c Levels in Elderly Patients with Diabetes

open access: yesActa Medica Indonesiana, 2016
Aim: to obtain information on the proportion of orthostatic hypotension in elderly patients with diabetes and its relationship with HbA1c levels. Methods: this is a cross-sectional study on 350 patients with diabetes mellitus (DM) aged ≥60 years old who ...
Catarina Budyono   +3 more
doaj  

Predicting Blood Pressure Response to Fluid Bolus Therapy Using Attention-Based Neural Networks for Clinical Interpretability [PDF]

open access: yesarXiv, 2018
Determining whether hypotensive patients in intensive care units (ICUs) should receive fluid bolus therapy (FBT) has been an extremely challenging task for intensive care physicians as the corresponding increase in blood pressure has been hard to predict. Our study utilized regression models and attention-based recurrent neural network (RNN) algorithms
arxiv  

Automatic lesion analysis for increased efficiency in outcome prediction of traumatic brain injury [PDF]

open access: yesarXiv, 2022
The accurate prognosis for traumatic brain injury (TBI) patients is difficult yet essential to inform therapy, patient management, and long-term after-care. Patient characteristics such as age, motor and pupil responsiveness, hypoxia and hypotension, and radiological findings on computed tomography (CT), have been identified as important variables for ...
arxiv  

Vitamin D and orthostatic hypotension [PDF]

open access: yesAge and Ageing, 2012
we aimed to investigate on the potential relationship between vitamin D and orthostatic hypotension (OH) in a case-control model in older adults.all participants were community-dwelling adults who were not taking vitamin D supplements. Cases were subjects aged 64 or older who were diagnosed with OH at a Falls and Blackout Unit.
Kevin McCarroll   +5 more
openaire   +5 more sources

NLX‐112 Randomized Phase 2A Trial: Safety, Tolerability, Anti‐Dyskinetic, and Anti‐Parkinsonian Efficacy

open access: yesMovement Disorders, EarlyView.
Abstract Background Levodopa‐induced dyskinesia (LID) in Parkinson's disease (PD) is associated with ‘false neurotransmitter’ release of dopamine from serotonin (5‐HT) neurons. NLX‐112 is a first‐in‐class, highly selective 5‐HT1A receptor agonist which counteracts LIDs in experimental PD models.
Per Svenningsson   +13 more
wiley   +1 more source

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