Characteristics, Management, and Outcomes of Hospitalized Patients with Orthostatic Hypotension. [PDF]
ABSTRACT Orthostatic hypotension (OH) is a common inpatient condition associated with falls, syncope, and mortality. However, standardized approaches for inpatient management of OH are lacking and may vary across clinical specialties. In this retrospective observational cohort study, we reviewed the electronic medical records of patients admitted to ...
Wagner BA+5 more
europepmc +2 more sources
PURL: Best timing for measuring orthostatic vital signs? [PDF]
Phipps D+8 more
europepmc +1 more source
Recurrent Subdural Hematoma: A Case Report of Diagnostic Pitfall of Spontaneous Intracranial Hypotension and Successful Management With Targeted Epidural Blood Patch. [PDF]
ABSTRACT Spontaneous intracranial hypotension should be considered in subdural hematoma cases without cerebral trauma or underlying disease, particularly among non‐elderly patients. Targeted epidural blood patch is recommended as a first‐line intervention prior to surgical management in cases of spontaneous intracranial hypotension‐induced subdural ...
Chen L, Ying G, Peng Y.
europepmc +2 more sources
Utilizing the Boston Syncope Observation Management Pathway to Reduce Hospital Admission and Decrease Adverse Outcomes [PDF]
Introduction: In an age of increasing scrutiny of each hospital admission, emergency department (ED) observation has been identified as a low-cost alternative. Prior studies have shown admission rates for syncope in the United States to be as high as 70%.
Grossman, Shamai A.+7 more
core +2 more sources
Neurovisceral phenotypes in the expression of psychiatric symptoms [PDF]
This review explores the proposal that vulnerability to psychological symptoms, particularly anxiety, originates in constitutional differences in the control of bodily state, exemplified by a set of conditions that include Joint Hypermobility, Postural ...
Aktas+132 more
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Randomised clinical trial: Polyethylene glycol 3350 with sports drink vs. polyethylene glycol with electrolyte solution as purgatives for colonoscopy--the incidence of hyponatraemia. [PDF]
BACKGROUND: Polyethylene glycol 3350 plus sports drink (PEG-SD) is a hypo-osmotic purgative commonly used for colonoscopy, though little safety data are available. AIM: To evaluate the effect of PEG-SD on serum sodium (Na) and other electrolytes compared
Aronchick+18 more
core +2 more sources
The effect of elastic abdominal binder use on respiratory function on persons with high spinal cord injury at orthostatic position [PDF]
Introduction : Spinal cord injury causes respiratory muscles paralysis, especially in high thoracic paraplegia and tetraplegia with injury above or right on the sixth thoracic segment, and also biomechanics, volumes, capacities and respiratory pressures ...
Cardoso, Jefferson R.+4 more
core +1 more source
A Young Female Who Develops Tachycardia and Orthostatic Intolerance Following a Recent Infection [PDF]
Case Presentation The patient is a 20-year-old female with a history of asthma and anxiety with panic attacks who presented with palpitations and lightheadedness/pre-syncope. The morning of admission, she was attending a seminar and experienced an acute
Valentino, MD, PhD, Michael A.
core +2 more sources
First-in-human safety, tolerability, pharmacokinetics and pilot food-effect study of the candidate antimalarial compound MMV367. [PDF]
Abstract Aim To evaluate the safety, tolerability and pharmacokinetics in healthy participants of orally administered MMV367 (GSK3772701), a novel antimalarial interfering with Plasmodium falciparum acyl coenzyme A synthetase 10/11 function. Methods This first‐in‐human study enrolled 47 healthy male and female participants.
Kuemmerle A+13 more
europepmc +2 more sources