Results 11 to 20 of about 8,495 (166)

Clinical Assessment of Fluid Status in Adults With Acute Kidney Injury: A Scoping Review. [PDF]

open access: yesJ Ren Care
ABSTRACT Background Acute kidney injury refers to sudden, potentially reversible, reduction in kidney function. Hypovolaemia is commonly the major risk factor. When acute kidney injury is established, fluid can accumulate leading to fluid overload. Undertaking a rigorous fluid assessment is vital in the management of a patient in hospital with acute ...
Nagalingam K   +4 more
europepmc   +2 more sources

First-in-human safety, tolerability, pharmacokinetics and pilot food-effect study of the candidate antimalarial compound MMV367. [PDF]

open access: yesBr J Clin Pharmacol
Abstract Aim To evaluate the safety, tolerability and pharmacokinetics in healthy participants of orally administered MMV367 (GSK3772701), a novel antimalarial interfering with Plasmodium falciparum acyl coenzyme A synthetase 10/11 function. Methods This first‐in‐human study enrolled 47 healthy male and female participants.
Kuemmerle A   +13 more
europepmc   +2 more sources

PURL: Best timing for measuring orthostatic vital signs? [PDF]

open access: closedJ Fam Pract, 2019
Phipps D   +8 more
europepmc   +1 more source

Postural orthostatic tachycardia syndrome and other related dysautonomic disorders after SARS-CoV-2 infection and after COVID-19 messenger RNA vaccination

open access: yesFrontiers in Neurology, 2023
The COVID-19 pandemic has caused a challenge for our society due to the post-acute sequelae of the disease. Persistent symptoms and long-term multiorgan complications, known as post-acute COVID-19 syndrome, can occur beyond 4 weeks from the onset of the ...
Elisabeth Gómez-Moyano   +19 more
doaj   +1 more source

CD-19 CART therapy and orthostatic hypotension: a single center retrospective cohort study

open access: yesCardio-Oncology, 2022
Background Chimeric antigen receptor T-cell (CART) therapy is a form of cellular immunotherapy used to treat hematologic malignancies. Major adverse cardiovascular events have been seen in CART patients who have high grade CRS, higher baseline creatinine,
Ashish Patel   +4 more
doaj   +1 more source

Cardiac Amyloidosis: A Rare TTR Mutation Found in an Asian Female

open access: yesJournal of Cardiovascular Development and Disease, 2023
Background: Transthyretin cardiac amyloidosis (ATTR) is a life-threatening, debilitating disease caused by abnormal formation and deposit of transthyretin (TTR) protein in multiple tissues, including myocardial extracellular matrix. It can be challenging
Kristina Mouksian   +5 more
doaj   +1 more source

Poincaré plot can help predict the curative effect of metoprolol for pediatric postural orthostatic tachycardia syndrome

open access: yesFrontiers in Neuroscience, 2023
PurposeTo study whether a Poincaré plot can help predict the curative effect of metoprolol for postural orthostatic tachycardia syndrome (POTS) in children.MethodsPediatric patients with POTS who were administered metoprolol were retrospectively included.
Piaoliu Yuan   +9 more
doaj   +1 more source

Integrative Volume Status Assessment

open access: yesPOCUS Journal, 2022
Volume status assessment is a critical but challenging clinical skill and is especially important for the management of patients in the emergency department, intensive care unit, and dialysis unit where accurate intravascular assessment is necessary to ...
David Kearney   +2 more
doaj   +1 more source

Trauma and syncope: looking beyond the injury

open access: yesTrauma Surgery & Acute Care Open, 2023
Background 42% of the population experience syncope by the age of 70, accounting for up to 6% of hospital admissions that frequently present as falls.
Kieran S Kavi, Nicholas P Gall
doaj   +1 more source

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