Movement Disorders, Volume 40, Issue 6, Page 1134-1142, June 2025.Abstract Background Levodopa‐induced dyskinesia (LID) in Parkinson's disease (PD) is associated with ‘false neurotransmitter’ release of dopamine from serotonin (5‐HT) neurons. NLX‐112 is a first‐in‐class, highly selective 5‐HT1A receptor agonist which counteracts LIDs in experimental PD models.
Per Svenningsson +13 more
wiley +1 more source
Catechol-O-methyltransferase inhibition with tolcapone reduces the "wearing off" phenomenon and levodopa requirements in fluctuating parkinsonian patients. [PDF]
, 1997 BACKGROUND: More than 50% of patients with Parkinson's disease develop motor response fluctuations (the "wearing off" phenomenon) after more than five years of levodopa therapy.
Baas, H. +6 more
core +1 more source
Sociology of Health &Illness, Volume 47, Issue 5, June 2025.ABSTRACT For many living with chronic illness, COVID‐19 is a compounding health crisis. Although a few studies have focused on the experiences of those living with chronic illness, this is the first to prioritise the voices of women living with chronic illnesses during the pandemic.
Holly Thorpe, Grace O'Leary
wiley +1 more source
Neurocardiogenic syncope in the intercollegiate athlete : an examination of problems and solutions : an honors thesis (HONRS 499) [PDF]
, 2000 Neurocardiogenic Syncope, a condition common in young people, is becoming more recognized in the Athletic Training profession. The purpose of this discussion is to delve into this condition and provide basic knowledge to help the Athletic Trainer manage ...
Zickgraf, Sara E.
core
Sympathetic activity and early mobilization in patients in intensive and intermediate care with severe brain injuries: a preliminary prospective randomized study. [PDF]
, 2016 Patients who experience severe brain injuries are at risk of secondary brain damage, because of delayed vasospasm and edema. Traditionally, many of these patients are kept on prolonged bed rest in order to maintain adequate cerebral blood flow ...
Berney, L. +10 more
core +4 more sources
The effect of bedrest on various parameters of physiological function. Part X - The effect of bedrest on the circulatory response to a valsalva maneuver [PDF]
Quantitative arterial blood pressure change during Valsalva maneuver after bed ...
Cardus, D. +3 more
core +1 more source
THE PREVALENCE OF ORTHOSTATIC HYPOTENSION AMONG HOSPITALIZED OLDER ADULTS AT RISK FOR FALLING
Innovation in aging, 2019 Orthostatic hypotension (OH) may cause falls in hospitalized older adults. OH is a sustained drop of at least 20 mm Hg for systolic blood pressure or at least 10 mm Hg for diastolic blood pressure when changing position from supine to sitting, sitting to
Denise L Lyons, K. Schell
semanticscholar +1 more source
Clinical Autonomic Research, 2017 Mrs. A is a 50-year-old married woman who first presented 3 years ago for consultation because of recurrent orthostatic lightheadedness and two brief syncopal episodes.
F. Gupta +3 more
semanticscholar +1 more source
Cerebrovascular Accident Caused by Embolic Atrial Myxoma [PDF]
, 2013 Background: Atrial myxomas, the most common type of cardiac tumors, can cause life-threatening complications. As most cardiac myxomas are surgically curable, early diagnosis is crucial. Cardiac tumors can present with cardiac and embolic manifestations,
Garrett, MD, Andrew, Han, MD, Eugene
core +2 more sources
, 2012 Although the assessment of dynamic cerebral autoregulation (CA) based on measurements of spontaneous fluctuations in arterial blood pressure (ABP) and cerebral blood flow (CBF) is a convenient and much used method, there remains uncertainty about its ...
Allen, Robert +7 more
core +1 more source